Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Florian A. Gegenfurtner"'
Autor:
Bojan Ljepoja, Christoph Schreiber, Florian A Gegenfurtner, Jonathan García-Roman, Bianca Köhler, Stefan Zahler, Joachim O Rädler, Ernst Wagner, Andreas Roidl
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224314 (2019)
Cancer progression and metastases are frequently related to changes of cell motility. Amongst others, the microRNA-200c (miR-200c) was shown to maintain the epithelial state of cells and to hamper migration. Here, we describe two miR-200c inducible b
Externí odkaz:
https://doaj.org/article/1fd649239240459e99eae4b55d1facc4
Autor:
Angelika M. Vollmar, Adrian Fuchs, Hanna Engelke, Florian A. Gegenfurtner, Bernhard Illes, Stefan Zahler, Evelyn Ploetz
Publikováno v:
iScience
iScience, Vol 24, Iss 3, Pp 102185-(2021)
iScience, Vol 24, Iss 3, Pp 102185-(2021)
Summary The mechanical properties of the extracellular matrix strongly influence tumor progression and invasion. Yes-associated protein (YAP) has been shown to be a key regulator of this process translating mechanical cues from the extracellular matr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027d129cb23fd8e39bdbb9c61e9f058e
http://europepmc.org/articles/PMC7921841
http://europepmc.org/articles/PMC7921841
Autor:
Themistoklis Zisis, Christoph Müller, Christian Grimm, Nicole Urban, Franz Bracher, Martin Müller, Cheng-Chang Chen, Susanne Gerndt, Florian A. Gegenfurtner, Yu-Kai Chao, Karin Bartel, Franz Geisslinger, Martin Biel, Ong Nam Phuong Nguyen, Stefan Zahler, Michael Schaefer, Angelika M. Vollmar, Aaron Gerwien, Carina Ortler
Publikováno v:
Cell chemical biology. 28(8)
Summary The role of two-pore channel 2 (TPC2), one of the few cation channels localized on endolysosomal membranes, in cancer remains poorly understood. Here, we report that TPC2 knockout reduces proliferation of cancer cells in vitro, affects their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd72207afce50f8e10800e33f05948fa
https://pubmed.ncbi.nlm.nih.gov/34416140
https://pubmed.ncbi.nlm.nih.gov/34416140
Autor:
Dirk Trauner, Florian Küllmer, Veselin Nasufovic, Oliver Thorn-Seshold, Florian A. Gegenfurtner, Malgorzata Borowiak, Sebastian Peil, Hans-Dieter Arndt, Stefan Zahler
Publikováno v:
J Am Chem Soc
The spatiotemporally-controlled perturbation of cellular function using photopharmacology has facilitated the elucidation of biological networks and opens up new opportunities for precision medicine. Here, we introduce cell- permeable photoswitchable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6cb369665c451fcadd89fe4a1039ced
https://europepmc.org/articles/PMC8023282/
https://europepmc.org/articles/PMC8023282/
Autor:
Waldemar Schrimpf, Christoph Ziegenhain, Angelika M. Vollmar, Florian A. Gegenfurtner, Themistoklis Zisis, Wolfgang Enard, Don C. Lamb, Uli Kazmaier, Stefan Zahler, Zane Kliesmete, Nader Al Danaf
Publikováno v:
Cellular and Molecular Life Sciences. 75:4539-4555
Actin has emerged as a versatile regulator of gene transcription. Cytoplasmatic actin regulates mechanosensitive-signaling pathways such as MRTF-SRF and Hippo-YAP/TAZ. In the nucleus, both polymerized and monomeric actin directly interfere with trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b292f40fb475083e4b650717818895
https://doi.org/10.1007/s00018-018-2919-4
https://doi.org/10.1007/s00018-018-2919-4
Autor:
Christoph Ziegenhain, Stefan Zahler, Florian A. Gegenfurtner, Rolf Müller, Shuaijun Wang, Zane Kliesmete, Angelika M. Vollmar, Sabine Schneider, Alvaro H. Crevenna, Wolfgang Enard
Publikováno v:
Journal of natural products
Actin is a protein of central importance for many cellular key processes. It is regulated by local interactions with a large number of actin binding proteins (ABPs). Various compounds are known to either increase or decrease the polymerization dynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d43b4f8061dcc9cac92a1294b049ba
https://pubmed.ncbi.nlm.nih.gov/31260301
https://pubmed.ncbi.nlm.nih.gov/31260301
Autor:
Lisa Pfitzer, Angelika M. Vollmar, Rebekka Kubisch-Dohmen, Rebecca Smith, Christina Moser, Themistoklis Zisis, Gyula Timinszky, Stefan Zahler, Olga V. Kalinina, Florian A. Gegenfurtner, Anja Arner, Johanna Busse, Ernst Wagner, Rolf Müller, Carina Atzberger, Florian Foerster
Publikováno v:
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2019, 10 (4), pp.302. ⟨10.1038/s41419-019-1546-9⟩
Cell death & disease
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 4, Pp 1-14 (2019)
Cell Death and Disease, 2019, 10 (4), pp.302. ⟨10.1038/s41419-019-1546-9⟩
Cell Death and Disease, Nature Publishing Group, 2019, 10 (4), pp.302. ⟨10.1038/s41419-019-1546-9⟩
Cell death & disease
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 4, Pp 1-14 (2019)
Cell Death and Disease, 2019, 10 (4), pp.302. ⟨10.1038/s41419-019-1546-9⟩
Severe side effects often restrict clinical application of the widely used chemotherapeutic drug doxorubicin. In order to decrease required substance concentrations, new concepts for successful combination therapy are needed. Since doxorubicin causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fefd39517fd0521019e9c1bc9b0cc57
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02119228/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02119228/document
Autor:
Angelika M. Vollmar, Florian A. Gegenfurtner, Christoph Schreiber, Felix J. Segerer, Simon Schuster, Kerstin Kick, Joachim O. Rädler, Stefan Zahler, Max Albert
Publikováno v:
Biomaterials. 102:137-147
Recent reports demonstrated that migration in fibrillary environments can be mimicked by spatial confinement achieved with micro-patterning [1]. Here we investigated whether a model system based on linearly structured surfaces allows to draw conclusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf6118826e5c6d9715aa354ddd8c092
https://doi.org/10.1016/j.biomaterials.2016.06.021
https://doi.org/10.1016/j.biomaterials.2016.06.021
Autor:
Maria Hoyer, Uli Kazmaier, Angelika M. Vollmar, Iris Antes, Antoine Marion, Wolfgang Enard, Christoph Ziegenhain, Alvaro H. Crevenna, Ilke Ugur, Stefan Zahler, Shuaijun Wang, Zane Kliesmete, Don C. Lamb, Florian A. Gegenfurtner
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Actin binding compounds are widely used tools in cell biology. We compare the biological and biochemical effects of miuraenamide A and jasplakinolide, a structurally related prototypic actin stabilizer. Though both compounds have similar effects on c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2817b84a73207354c598bde14895fb90
https://mediatum.ub.tum.de/doc/1544429/document.pdf
https://mediatum.ub.tum.de/doc/1544429/document.pdf
Autor:
Angelika M. Vollmar, Helga Wagner, Stefan Zahler, Wolfgang Enard, Florian A. Gegenfurtner, Bérénice Jahn, Ludwig Geistlinger, Christoph Ziegenhain, Joachim O. Rädler
Publikováno v:
Journal of Cell Science.
Developmental processes, such as angiogenesis, are associated with a constant remodeling of the actin cytoskeleton in response to different mechanical stimuli. The mechanosensitive transcription factors MRTF-A (MKL1) and YAP (also known as YAP1) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b4a5f4ca7718984aa0f16c1d6da961
https://doi.org/10.1242/jcs.212886
https://doi.org/10.1242/jcs.212886