Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Florian A Lempp"'
Autor:
Yi Ni, Zhenfeng Zhang, Lisa Engelskircher, Georg Verch, Thomas Tu, Florian A. Lempp, Stephan Urban
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Abstract Human hepatitis delta virus (HDV) causes the most severe form of viral hepatitis. Approximately 15–25 million people are chronically infected with HDV. As a satellite virus of the human hepatitis B virus (HBV), HDV uses the HBV-encoded env
Externí odkaz:
https://doaj.org/article/30ccad5c8a38486fb94b4a7814b23893
Autor:
Florian A. Lempp, Franziska Schlund, Lisa Rieble, Lea Nussbaum, Corinna Link, Zhenfeng Zhang, Yi Ni, Stephan Urban
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Hepatitis delta virus (HDV) depends on the envelope proteins of hepatitis B virus (HBV) for virion production. Here, Lempp et al. produce a cell line expressing HBV envelope proteins and their receptor, which allows continuous secretion of infectious
Externí odkaz:
https://doaj.org/article/0b4c7b835d4c4558b301caf070bd4e81
Autor:
Florian A. Lempp, Imme Roggenbach, Shirin Nkongolo, Volkan Sakin, Franziska Schlund, Paul Schnitzler, Heiner Wedemeyer, Frédéric Le Gal, Emmanuel Gordien, Cihan Yurdaydin, Stephan Urban
Publikováno v:
Viruses, Vol 13, Iss 12, p 2371 (2021)
Hepatitis Delta virus (HDV) is a satellite of the Hepatitis B virus (HBV) and causes severe liver disease. The estimated prevalence of 15–20 million infected people worldwide may be underestimated as international diagnostic guidelines are not rout
Externí odkaz:
https://doaj.org/article/2d17ee1681cd459ea5c41bb30a988800
Autor:
Imme Roggenbach, Xiumei Chi, Florian A. Lempp, Bingqian Qu, Lisa Walter, Ruihong Wu, Xiuzhu Gao, Paul Schnitzler, Yanhua Ding, Stephan Urban, Junqi Niu
Publikováno v:
Viruses, Vol 13, Iss 9, p 1799 (2021)
HDV infection causes severe liver disease, the global health burden of which may be underestimated due to limited epidemiological data. HDV depends on HBV for infection, but recent studies indicated that dissemination can also be supported by other h
Externí odkaz:
https://doaj.org/article/905e8885bb414562a4ae3bf03105a237
Autor:
Amin Addetia, Luca Piccoli, James Brett Case, Young-Jun Park, Martina Beltramello, Barbara Guarino, Ha Dang, Dora Pinto, Suzanne M. Scheaffer, Kaitlin Sprouse, Jessica Bassi, Chiara Silacci-Fregni, Francesco Muoio, Marco Dini, Lucia Vincenzetti, Rima Acosta, Daisy Johnson, Sambhavi Subramanian, Christian Saliba, Martina Giurdanella, Gloria Lombardo, Giada Leoni, Katja Culap, Carley McAlister, Anushka Rajesh, Exequiel Dellota, Jiayi Zhou, Nisar Farhat, Dana Bohan, Julia Noack, Florian A. Lempp, Elisabetta Cameroni, Bradley Whitener, Olivier Giannini, Alessandro Ceschi, Paolo Ferrari, Alessandra Franzetti-Pellanda, Maira Biggiogero, Christian Garzoni, Stephanie Zappi, Luca Bernasconi, Min Jeong Kim, Gretja Schnell, Nadine Czudnochowski, Nicholas Franko, Jennifer K. Logue, Courtney Yoshiyama, Cameron Stewart, Helen Chu, Michael A. Schmid, Lisa A. Purcell, Gyorgy Snell, Antonio Lanzavecchia, Michael S. Diamond, Davide Corti, David Veesler
Publikováno v:
bioRxiv
Currently circulating SARS-CoV-2 variants acquired convergent mutations at receptor-binding domain (RBD) hot spots1. Their impact on viral infection, transmission, and efficacy of vaccines and therapeutics remains poorly understood. Here, we demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce29f8388403bbef8bf55f16166bdbea
https://europepmc.org/articles/PMC9882201/
https://europepmc.org/articles/PMC9882201/
Autor:
Young-Jun Park, Dora Pinto, Alexandra C. Walls, Zhuoming Liu, Anna De Marco, Fabio Benigni, Fabrizia Zatta, Chiara Silacci-Fregni, Jessica Bassi, Kaitlin R. Sprouse, Amin Addetia, John E. Bowen, Cameron Stewart, Martina Giurdanella, Christian Saliba, Barbara Guarino, Michael A. Schmid, Nicholas M. Franko, Jennifer K. Logue, Ha V. Dang, Kevin Hauser, Julia di Iulio, William Rivera, Gretja Schnell, Anushka Rajesh, Jiayi Zhou, Nisar Farhat, Hannah Kaiser, Martin Montiel-Ruiz, Julia Noack, Florian A. Lempp, Javier Janer, Rana Abdelnabi, Piet Maes, Paolo Ferrari, Alessandro Ceschi, Olivier Giannini, Guilherme Dias de Melo, Lauriane Kergoat, Hervé Bourhy, Johan Neyts, Leah Soriaga, Lisa A. Purcell, Gyorgy Snell, Sean P. J. Whelan, Antonio Lanzavecchia, Herbert W. Virgin, Luca Piccoli, Helen Y. Chu, Matteo Samuele Pizzuto, Davide Corti, David Veesler
Publikováno v:
Science
Science, 2022, pp.First release. ⟨10.1126/science.adc9127⟩
bioRxiv
Science, 2022, pp.First release. ⟨10.1126/science.adc9127⟩
bioRxiv
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry distinct spike mutations resulting in escape from antibodies induced by previous infection or vaccination. We show that hybrid immunity or vaccine boosters elicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a35e4a51f14a3fa4984e4ce4734fe2
https://hal-pasteur.archives-ouvertes.fr/pasteur-03827707/file/science.adc9127.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03827707/file/science.adc9127.pdf
Autor:
Florian A. Lempp, Tassilo Volz, Elisabetta Cameroni, Fabio Benigni, Jiayi Zhou, Laura E. Rosen, Julia Noack, Fabrizia Zatta, Hannah Kaiser, Siro Bianchi, Gloria Lombardo, Stefano Jaconi, Hasan Imam, Leah B. Soriaga, Nadia Passini, David M. Belnap, Andreas Schulze, Marc Lütgehetmann, Amalio Telenti, Andrea L. Cathcart, Gyorgy Snell, Lisa A. Purcell, Christy M. Hebner, Stephan Urban, Maura Dandri, Davide Corti, Michael A. Schmid
Background & AimsChronic hepatitis B is a major global public health problem, and coinfection with hepatitis delta virus (HDV) worsens disease outcome. Here, we describe a hepatitis B virus (HBV) surface antigen (HBsAg)-targeting monoclonal antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fec46ca7004efc0b3dbdb32e584ca22
https://doi.org/10.1101/2022.09.09.507326
https://doi.org/10.1101/2022.09.09.507326
Autor:
Antonio Lanzavecchia, Lisa A. Purcell, Young-Jun Park, Nuria Izquierdo-Useros, Siro Bianchi, Stefano Jaconi, Marcel Meury, Maria De Agostini, Exequiel Dellota, Davide Corti, Fabio Benigni, David Veesler, Amalio Telenti, Elisabetta Cameroni, Florian A. Lempp, Herbert W. Virgin, Júlia Vergara-Alert, Martin Montiel-Ruiz, Hannah Kaiser, Jiayi Zhou, Javier Martinez-Picado, Anshu Joshi, Julia Noack, Alexandra C. Walls, Leah Soriaga, John E. Bowen
Publikováno v:
Nature. 598:342-347
SARS-CoV-2 infection—which involves both cell attachment and membrane fusion—relies on the angiotensin-converting enzyme 2 (ACE2) receptor, which is paradoxically found at low levels in the respiratory tract1–3, suggesting that there may be add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::929d95353fc5888accfa2ab12b173d19
https://doi.org/10.1038/s41586-021-03925-1
https://doi.org/10.1038/s41586-021-03925-1
Autor:
Yesseinia I. Anglero-Rodriguez, Florian A. Lempp, James McIninch, Mark K. Schlegel, Christopher R. Brown, Donald J. Foster, Adam B. Castoreno, Tuyen Nguyen, Megha Subramanian, Martin Montiel-Ruiz, Hannah Kaiser, Anna Sahakyan, Roberto Spreafico, Svetlana Shulga Morskaya, Joseph D. Barry, Daniel Berman, Stephanie Lefebvre, Anne Kasper, Timothy Racie, Diann Weddle, Melissa Mobley, Arlin Rogers, Joseph Dybowski, Saeho Chong, Jayaprakash Nair, Amy Simon, Kevin Sloan, Seungmin Hwang, Herbert W. Virgin, Kevin Fitzgerald, Martin A. Maier, Gregory Hinkle, Christy M. Hebner, Akin Akinc, Vasant Jadhav
RNA interference is a natural antiviral mechanism that could be harnessed to combat SARS-CoV-2 infection by targeting and destroying the viral genome. We screened lipophilic small-interfering RNA (siRNA) conjugates targeting highly conserved regions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd2ebe031d135cd9e0bfc23cecf5156
https://doi.org/10.1101/2022.03.20.485044
https://doi.org/10.1101/2022.03.20.485044
Autor:
M. Cyrus Maher, Istvan Bartha, Steven Weaver, Julia di Iulio, Elena Ferri, Leah Soriaga, Florian A. Lempp, Brian L. Hie, Bryan Bryson, Bonnie Berger, David L. Robertson, Gyorgy Snell, Davide Corti, Herbert W. Virgin, Sergei L. Kosakovsky Pond, Amalio Telenti
Publikováno v:
Science Translational Medicine. 14
SARS-CoV-2 evolution threatens vaccine- and natural infection-derived immunity as well as the efficacy of therapeutic antibodies. To improve public health preparedness, we sought to predict which existing amino acid mutations in SARS-CoV-2 might cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce7b85b58f181da325360aefe2e35a9
https://doi.org/10.1126/scitranslmed.abk3445
https://doi.org/10.1126/scitranslmed.abk3445