Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Florian, Uhle"'
Autor:
Julia Jehn, Franziska Trudzinski, Rastislav Horos, Judith Schenz, Florian Uhle, Markus A. Weigand, Maurice Frank, Mustafa Kahraman, Marco Heuvelman, Tobias Sikosek, Timothy Rajakumar, Jennifer Gerwing, Jasmin Skottke, Alberto Daniel-Moreno, Christina Rudolf, Franziska Hinkfoth, Kaja Tikk, Petros Christopoulos, Laura V. Klotz, Hauke Winter, Michael Kreuter, Bruno R. Steinkraus
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract miR-Blood is a high-quality, small RNA expression atlas for the major components of human peripheral blood (plasma, erythrocytes, thrombocytes, monocytes, neutrophils, eosinophils, basophils, natural killer cells, CD4+ T cells, CD8+ T cells,
Externí odkaz:
https://doaj.org/article/63ada786f52c4fc798ff8737ea2cdea0
Autor:
Emmanuel Schneck, Fabian Edinger, Florian Uhle, Melanie Markmann, Andreas Hecker, Markus A. Weigand, Michael Sander, Christian Koch
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The early identification of sepsis in surgical intensive care patients is challenging due to the physiological postoperative alterations of vital signs and inflammatory biomarkers. Soluble Delta-like protein 1 (sDLL1) may be a potential disc
Externí odkaz:
https://doaj.org/article/8b35466365f6455c99e08499058e2077
Autor:
Christian Nusshag, Changli Wei, Eunsil Hahm, Salim S. Hayek, Jing Li, Beata Samelko, Christoph Rupp, Roman Szudarek, Claudius Speer, Florian Kälble, Matthias Schaier, Florian Uhle, Felix C.F. Schmitt, Mascha O. Fiedler, Ellen Krautkrämer, Yanxia Cao, Ricardo Rodriguez, Uta Merle, Jesper Eugen-Olsen, Martin Zeier, Markus A. Weigand, Christian Morath, Thorsten Brenner, Jochen Reiser
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Acute kidney injury (AKI) secondary to sepsis results in poor outcomes and conventional kidney function indicators lack diagnostic value. Soluble urokinase plasminogen activator receptor (suPAR) is an innate immune–derived molecule implicated in in
Externí odkaz:
https://doaj.org/article/4d103726f05d4f84ae5ff657e01e292f
Autor:
Timothy Rajakumar, Rastislav Horos, Julia Jehn, Judith Schenz, Thomas Muley, Oana Pelea, Sarah Hofmann, Paul Kittner, Mustafa Kahraman, Marco Heuvelman, Tobias Sikosek, Jennifer Feufel, Jasmin Skottke, Dennis Nötzel, Franziska Hinkfoth, Kaja Tikk, Alberto Daniel-Moreno, Jessika Ceiler, Nathaniel Mercaldo, Florian Uhle, Sandra Uhle, Markus A. Weigand, Mariam Elshiaty, Fabienne Lusky, Hannah Schindler, Quentin Ferry, Tatjana Sauka-Spengler, Qianxin Wu, Klaus F. Rabe, Martin Reck, Michael Thomas, Petros Christopoulos, Bruno R. Steinkraus
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-13 (2022)
Abstract Immunotherapies have recently gained traction as highly effective therapies in a subset of late-stage cancers. Unfortunately, only a minority of patients experience the remarkable benefits of immunotherapies, whilst others fail to respond or
Externí odkaz:
https://doaj.org/article/db0758eed23b499e84eeb809e4369d62
Autor:
Alan Bénard, Frederik J. Hansen, Florian Uhle, Bettina Klösch, Franziska Czubayko, Anke Mittelstädt, Anne Jacobsen, Paul David, Malgorzata J. Podolska, Anna Anthuber, Izabela Swierzy, Dominik Schaack, Petra Mühl-Zürbes, Alexander Steinkasserer, Michael Weyand, Markus A. Weigand, Thorsten Brenner, Christian Krautz, Robert Grützmann, Georg F. Weber
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
RationaleSepsis, a global health burden, is often complicated by viral infections leading to increased long-term morbidity and mortality. Interleukin-3 (IL-3) has been identified as an important mediator amplifying acute inflammation in sepsis; howev
Externí odkaz:
https://doaj.org/article/988fd711ccd94a5a8ad18188b16bf555
Autor:
Sushmita Chakraborty, Bianca Handrick, Dayoung Yu, Konrad A. Bode, Anna Hafner, Judith Schenz, Dominik Schaack, Florian Uhle, Taro Tachibana, Shigeki Kamitani, Thomas Vogl, Katharina F. Kubatzky
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
IntroductionThe bacterial protein toxin Pasteurella multocida toxin (PMT) mediates RANKL-independent osteoclast differentiation. Although these osteoclasts are smaller, their resorptive activity is high which helps in efficient destruction of nasal t
Externí odkaz:
https://doaj.org/article/88107bbf108748e8a4856b885d17e219
Autor:
Maximilian Dietrich, Sebastian Marx, Maik von der Forst, Thomas Bruckner, Felix C. F. Schmitt, Mascha O. Fiedler, Felix Nickel, Alexander Studier-Fischer, Beat P. Müller-Stich, Thilo Hackert, Thorsten Brenner, Markus A. Weigand, Florian Uhle, Karsten Schmidt
Publikováno v:
Perioperative Medicine, Vol 10, Iss 1, Pp 1-12 (2021)
Abstract Background Hyperspectral imaging (HSI) could provide extended haemodynamic monitoring of perioperative tissue oxygenation and tissue water content to visualize effects of haemodynamic therapy and surgical trauma. The objective of this study
Externí odkaz:
https://doaj.org/article/dcd588cc50e549edb4ed1eb40f82d4de
Autor:
Daniel Mayer, Marc Altvater, Judith Schenz, Rawa Arif, Matthias Karck, Florian Leuschner, Markus A. Weigand, Florian Uhle, Christoph Lichtenstern
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveCardiopulmonary bypass (CPB) can lead to systemic inflammation, which is associated with higher morbidity. Therefore, we investigated the metabolism of isolated blood monocytes before and after CPB compared to healthy controls.MethodsIn this
Externí odkaz:
https://doaj.org/article/a775e3012a454f1091e95847c15bc175
Autor:
Jan Larmann, Jessica Handke, Anna S. Scholz, Sarah Dehne, Christoph Arens, Hans-Jörg Gillmann, Florian Uhle, Johann Motsch, Markus A. Weigand, Henrike Janssen
Publikováno v:
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Preoperative risk prediction in patients at elevated cardiovascular risk shows limited accuracy. Platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) indicate systemic inflammation. Both have been investigat
Externí odkaz:
https://doaj.org/article/9b6e01d43e8e4e57abb04a748a8a00ed
Autor:
Judith Schenz, Lena Heilig, Tim Lohse, Lucas Tichy, Katharina Bomans, Michael Büttner, Markus A. Weigand, Florian Uhle
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Elevated blood lactate levels are frequently found in critically ill patients and thought to result from tissue hypoperfusion and cellular oxygen shortage. Considering the close relationship between immune cell function and intracellular metabolism,
Externí odkaz:
https://doaj.org/article/fc60e8d7faaa4f3fafc88866019d4f2a