Ru-Catalyzed (E)-Specific ortho-C–H Alkenylation of Arenecarboxylic Acids by Coupling with Alkenyl Bromides

Autor: Florian Papp, Lukas J. Gooßen, Guodong Zhang, Zhiyong Hu, Florian Belitz

Publikováno v: Organic Letters. 23:3541-3545

In the presence of [p-cymene)RuCl2]2, (E)-configured alkenyl bromides couple with aromatic carboxylates to form ortho-vinylbenzoic acids. This C-H vinylation proceeds in high yields without any activating phosphine ligands and has an excellent functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06c8a32a756e373b7c6aec4783b93fb5
https://doi.org/10.1021/acs.orglett.1c00956

A Nickel(II)-Mediated Thiocarbonylation Strategy for Carbon Isotope Labeling of Aliphatic Carboxamides

Autor: Troels Skrydstrup, Kim B. Jensen, Magnus Gustafsson, Aske S. Donslund, Florian Papp, Simon S. Pedersen, Jesper H. Mikkelsen, Oskar S. Bakholm

Publikováno v: Pedersen, S S, Donslund, A S, Mikkelsen, J H, Bakholm, O S, Papp, F, Jensen, K B, Gustafsson, M B F & Skrydstrup, T 2021, ' A Nickel(II)-Mediated Thiocarbonylation Strategy for Carbon Isotope Labeling of Aliphatic Carboxamides ', Chemistry-A European Journal, vol. 27, no. 24, pp. 7114-7123 . https://doi.org/10.1002/chem.202005261
Chemstry-a european journal

A series of pharmaceutically relevant small molecules and biopharmaceuticals bearing aliphatic carboxamides have been successfully labeled with carbon-13. Key to the success of this novel carbon isotope labeling technique is the observation that 13C-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a896600ec895595fc1841ec7c31246
https://pure.au.dk/portal/da/publications/a-nickeliimediated-thiocarbonylation-strategy-for-carbon-isotope-labeling-of-aliphatic-carboxamides(aee04236-769f-40ca-a0ff-27ee98949f92).html

Carbene complex formation versus cyclometallation from a phosphoryl-tethered methanide ruthenium complex

Autor: Michelle Schmidt, Viktoria H. Gessner, Kai-Stephan Feichtner, Florian Papp, Maurice Paaßen

Publikováno v: Journal of Organometallic Chemistry. 915:121235

An oxophosphoryl-substituted methanide ligand system for transition metal complexes has been synthesized and isolated as the sodium salt Na[Ph2P(O)–C(H)–SO2Ph]. This ligand features structural components known to enable the isolation of nucleophi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e31184be004e7faab858af865c47b17
https://doi.org/10.1016/j.jorganchem.2020.121235