Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Florian, Mair"'
Autor:
Marianne R. Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Stephan R. Vavricka, Sylvie Scharl, Petrus M. Gutte, Markus G. Grütter, Hans-Dietmar Beer, Emmanuel Contassot, Andrew C. Chan, Xuezhi Dai, David J. Rawlings, Florian Mair, Burkhard Becher, Werner Falk, Michael Fried, Gerhard Rogler, Michael Scharl
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/1a86c5abc8534e9cbf373703d4260d85
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 9, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/c213a3fa29474144a6e64ef4bfd66a63
Autor:
Jami R. Erickson, Florian Mair, Grace Bugos, Jody Martin, Aaron J. Tyznik, Margaret Nakamoto, Stefanie Mortimer, Martin Prlic
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100092- (2020)
Summary: By including oligonucleotide-labeled antibodies into high-throughput single-cell RNA-sequencing protocols, combined transcript and protein expression data can be acquired on the single-cell level. Here, we describe a protocol for the combine
Externí odkaz:
https://doaj.org/article/b4664e2be1b443d2b0d992b0be29777c
Autor:
Florian Mair, Jami R. Erickson, Valentin Voillet, Yannick Simoni, Timothy Bi, Aaron J. Tyznik, Jody Martin, Raphael Gottardo, Evan W. Newell, Martin Prlic
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: High-throughput single-cell RNA sequencing (scRNA-seq) has become a frequently used tool to assess immune cell heterogeneity. Recently, the combined measurement of RNA and protein expression was developed, commonly known as cellular indexing
Externí odkaz:
https://doaj.org/article/0e450745aa8b49b5b9100025ab4e67ec
Autor:
Martin Prlic, Natalie Stanley, Thomas Liechti, Thomas M. Ashhurst, Florian Mair, Sofie Van Gassen, Lukas M. Weber
Publikováno v:
Nature Immunology. 22:1190-1197
High-dimensional cytometry experiments measuring 20–50 cellular markers have become routine in many laboratories. The increased complexity of these datasets requires added rigor during the experimental planning and the subsequent manual and computa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de36e89e86592d7a4bdbcaf9736e8a18
https://doi.org/10.1038/s41590-021-01006-z
https://doi.org/10.1038/s41590-021-01006-z
Autor:
Thomas Liechti, Florian Mair
Publikováno v:
Cytometry Part A. 99:231-242
Professional antigen-presenting cells (APCs), which include dendritic cells (DCs) and monocytes are essential for inducing and steering adaptive T-cell responses. Recent technological developments in single-cell analysis have significantly advanced o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4df9711d795273081b024aef6a8dadf
https://doi.org/10.1002/cyto.a.24269
https://doi.org/10.1002/cyto.a.24269
Publikováno v:
Cytometry
Purpose and appropriate samples This 27‐color panel has been validated and optimized to comprehensively profile natural killer (NK) cells isolated from human tumors using a collagenase Type II‐based digestion protocol. We confirmed that detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dee46a99cfbffe147583e2911d4c52
http://europepmc.org/articles/PMC7702032
http://europepmc.org/articles/PMC7702032
Autor:
Jami R. Erickson, Terry Stevens-Ayers, Florian Mair, Bradley Edmison, Michael Boeckh, Philip Bradley, Martin Prlic
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(6)
Competition between antigen-specific T cells for peptide:MHC complexes shapes the ensuing T cell response. Mouse model studies provided compelling evidence that competition is a highly effective mechanism controlling the activation of naïve T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb6f3fbfbabad13e8e09a723fd7d36e
https://pubmed.ncbi.nlm.nih.gov/35105810
https://pubmed.ncbi.nlm.nih.gov/35105810
Autor:
Florian Mair, Stefanie Joller, Romy Hoeppli, Lucas Onder, Matthias Hahn, Burkhard Ludewig, Ari Waisman, Burkhard Becher
Publikováno v:
eLife, Vol 4 (2015)
γδ T cells contribute to first line immune defense, particularly through their ability for rapid production of proinflammatory cytokines. The cytokine profile of γδ T cells is hard-wired already during thymic development. Yet, the molecular pathw
Externí odkaz:
https://doaj.org/article/f483ffe6afa544adb76f98be213a45ce
Autor:
Ari Waisman, Pawel Durek, Nicole Puertas, Mir-Farzin Mashreghi, Marianne R. Spalinger, Stefan Floess, Mirjam Lutz, Ekaterina Friebel, Benedict Becher, Florian Ingelfinger, Florian Mair, Ana Amorim, Claudia Haftmann, Stefanie Schärli, Pascale Zwicky, Burkhard Becher, Jochen Huehn, René Riedel, Jan Kisielow, Brian P. Leung
Publikováno v:
Science Immunology. 6
Medullary thymic epithelial cells (mTECs) are key antigen-presenting cells mediating T cell tolerance to prevent harmful autoimmunity. mTECs both negatively select self-reactive T cells and promote...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f35fecd808f2c421a19daed277a4e0a9
https://doi.org/10.1126/sciimmunol.abf3111
https://doi.org/10.1126/sciimmunol.abf3111