Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Florian, Leuschner"'
Autor:
Dominika Bernáth-Nagy, Melek Sükran Kalinyaprak, Evangelos Giannitsis, Pál Ábrahám, Florian Leuschner, Norbert Frey, Jona Benjamin Krohn
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Cardiovascular disease (CVD) ranks among the primary contributors to worldwide mortality. Hence, the importance of constant research on new circulating biomarkers for the improvement of early diagnosis and prognostication of different CVDs and the de
Externí odkaz:
https://doaj.org/article/778e3d9b194f4409a942a63abc1da6b0
Autor:
Mateo Marin‐Cuartas, Suzanne de Waha, Manuela de la Cuesta, Salil V. Deo, Alexander Kaminski, Andreas Fach, Anna L. Meyer, Aron‐Frederik Popov, Christian Hagl, Dominik Joskowiak, Elmar W. Kuhn, Fabio Ius, Florian Leuschner, George Awad, Holger Thiele, Ali Abdalla, Jens Garbade, Joerg Ender, Katharina Wehrmann, Kaveh Eghbalzadeh, Keti Vitanova, Lenard Conradi, Mahmoud Diab, Marcus Franz, Martin Geyer, Massimiliano Meineri, Martin Misfeld, Mohamed Abdel‐Wahab, Oliver D. Bhadra, Rico Osteresch, Rodrigo Sandoval Boburg, Rüdiger Lange, Sergey Leontyev, Shekhar Saha, Steffen Desch, Sven Lehmann, Thilo Noack, Torsten Doenst, Michael A. Borger, Philipp Kiefer
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Externí odkaz:
https://doaj.org/article/543ed2cadfaf4707ba37d18f647e9459
Autor:
Mariana Shumliakivska, Guillermo Luxán, Inga Hemmerling, Marina Scheller, Xue Li, Carsten Müller-Tidow, Bianca Schuhmacher, Zhengwu Sun, Andreas Dendorfer, Alisa Debes, Simone-Franziska Glaser, Marion Muhly-Reinholz, Klara Kirschbaum, Jedrzej Hoffmann, Eike Nagel, Valentina O. Puntmann, Sebastian Cremer, Florian Leuschner, Wesley Tyler Abplanalp, David John, Andreas M. Zeiher, Stefanie Dimmeler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Hematopoietic mutations in epigenetic regulators like DNA methyltransferase 3 alpha (DNMT3A), play a pivotal role in driving clonal hematopoiesis of indeterminate potential (CHIP), and are associated with unfavorable outcomes in patients suf
Externí odkaz:
https://doaj.org/article/20a09696ec974f6db501fff88d7fff78
Autor:
Max Sauter, Jonas Haag, Cindy Bay, Florian Leuschner, Walter E. Haefeli, Tim Christian Kuhn, Jürgen Burhenne
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2745 (2023)
The calcium-dependent serine endoprotease PACE4 is evaluated as a therapeutic target for prostate cancer. The peptide Ac-[d-Leu]LLLRVK-amba inhibits PACE4 with high affinity and has shown efficacy in preclinical mice xenograft models of prostate canc
Externí odkaz:
https://doaj.org/article/da9826cd68554d59b8930fb0e8585ed5
Autor:
Maximilian Dietrich, Ana Antonovici, Tobias Hölle, Christian Nusshag, Anne-Christine Kapp, Alexander Studier-Fischer, Rawa Arif, Felix Nickel, Markus Alexander Weigand, Norbert Frey, Christoph Lichtenstern, Florian Leuschner, Dania Fischer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionKidney dysfunction is common in patients with aortic stenosis (AS) and correction of the aortic valve by transcatheter aortic valve implantation (TAVI) often affects kidney function. This may be due to microcirculatory changes.MethodsWe e
Externí odkaz:
https://doaj.org/article/556c86610c8546e08d8a3b2ddef71d53
Autor:
Judith Schenz, Katharina Rump, Benedikt Hermann Siegler, Inga Hemmerling, Tim Rahmel, Jan N. Thon, Hartmuth Nowak, Dania Fischer, Anna Hafner, Lucas Tichy, Katharina Bomans, Manja Meggendorfer, Björn Koos, Thilo von Groote, Alexander Zarbock, Mascha O. Fiedler, Johanna Zemva, Jan Larmann, Uta Merle, Michael Adamzik, Carsten Müller-Tidow, Torsten Haferlach, Florian Leuschner, Markus A. Weigand
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Clonal hematopoiesis of indeterminate potential (CHIP) leads to higher mortality, carries a cardiovascular risk and alters inflammation. All three aspects harbor overlaps with the clinical manifestation of COVID-19. This study aimed to identify the i
Externí odkaz:
https://doaj.org/article/f9dd616dac7b4b5daf992b3da5f01606
Autor:
Anton Klersy, Sören Meyer, Florian Leuschner, Thorsten Kessler, Markus Hecker, Andreas H. Wagner
Publikováno v:
Cells, Vol 12, Iss 15, p 1926 (2023)
Background: Homozygosity for the C allele of the −1T>C single nucleotide polymorphism (SNP) of the CD40 gene (rs1883832) is associated with susceptibility to coronary heart disease (CHD), enhanced CD40 expression, and shedding. The disintegrin meta
Externí odkaz:
https://doaj.org/article/8c6827eb1bc7442182e2060cd976b869
Autor:
Etienne Boileau, Xue Li, Isabel S Naarmann-de Vries, Christian Becker, Ramona Casper, Janine Altmüller, Florian Leuschner, Christoph Dieterich
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
We introduce Single-cell Nanopore Spatial Transcriptomics (scNaST), a software suite to facilitate the analysis of spatial gene expression from second- and third-generation sequencing, allowing to generate a full-length near-single-cell transcription
Externí odkaz:
https://doaj.org/article/2b2183ae1a7843588cbdcd0db910366c
Autor:
Daniel Mayer, Marc Altvater, Judith Schenz, Rawa Arif, Matthias Karck, Florian Leuschner, Markus A. Weigand, Florian Uhle, Christoph Lichtenstern
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveCardiopulmonary bypass (CPB) can lead to systemic inflammation, which is associated with higher morbidity. Therefore, we investigated the metabolism of isolated blood monocytes before and after CPB compared to healthy controls.MethodsIn this
Externí odkaz:
https://doaj.org/article/a775e3012a454f1091e95847c15bc175
Autor:
Rawa Arif, Aglaia Warninck, Mina Farag, Wiebke Sommer, Florian Leuschner, Norbert Frey, Matthias Karck, Gregor Warnecke, Nicolas A. Geis
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 9, p 285 (2022)
Objective: Little is known about the fate of bypass grafts to the right coronary system. To investigate the long-term patency of venous bypass grafts directed to the right coronary artery (RCA) based on postoperative angiograms and to identify predic
Externí odkaz:
https://doaj.org/article/9aef5ac5358d4c419d3c99c76e75d57d