Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Florian, Kreppel"'
Autor:
Jonghui Kim, Karla Hegener, Claudia Hagedorn, Daniel Weidinger, Kashin Jamal Jameel, Inga Marte Charlott Seuthe, Sabine Eichhorn, Florian Kreppel, Jonas Jae-Hyun Park, Jürgen Knobloch
Publikováno v:
BMC Molecular and Cell Biology, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Background Epithelial cells are an important part of the pathomechanism in chronic rhinosinusitis with nasal polyps. It is therefore essential to establish a robust method for the isolation and culture of epithelial cells from nasal polyps t
Externí odkaz:
https://doaj.org/article/304e50a68646407c9b03f07179f367f4
Autor:
Thilo Gambichler, David Schrama, Riina Käpynen, Sera S. Weyer-Fahlbusch, Jürgen C. Becker, Laura Susok, Florian Kreppel, Nessr Abu Rached
Publikováno v:
Vaccines, Vol 12, Iss 5, p 533 (2024)
Merkel cell carcinoma is a rare, aggressive skin cancer that mainly occurs in elderly and immunocompromised patients. Due to the success of immune checkpoint inhibition in MCC, the importance of immunotherapy and vaccines in MCC has increased in rece
Externí odkaz:
https://doaj.org/article/aca935283e7842faa73199b2bef58659
Autor:
Denice Weklak, Julian Tisborn, Maurin Helen Mangold, Raphael Scheu, Harald Wodrich, Claudia Hagedorn, Franziska Jönsson, Florian Kreppel
Publikováno v:
Viruses, Vol 15, Iss 11, p 2155 (2023)
To contain the spread of the SARS-CoV-2 pandemic, rapid development of vaccines was required in 2020. Rational design, international efforts, and a lot of hard work yielded the market approval of novel SARS-CoV-2 vaccines based on diverse platforms s
Externí odkaz:
https://doaj.org/article/9c051fa9814f47df9a98f77b9268f7b5
Autor:
Nora A. Bahlmann, Lena Mautner, Mona Hoyos, Erwan Sallard, Carola Berger, Alexandra Dangel, Franziska Jönsson, Johannes C. Fischer, Florian Kreppel, Wenli Zhang, Irene Esposito, Edwin Bölke, Armin Baiker, Anja Ehrhardt
Publikováno v:
Genes, Vol 14, Iss 7, p 1348 (2023)
As the MHC-I-pathway is key to antigen presentation to cytotoxic T-cells and, therefore, recognition by the host adaptive immune system, we hypothesized that SARS-CoV-2 including its Variants of Concern (VOCs), influences MHC-I expression on epitheli
Externí odkaz:
https://doaj.org/article/d666a30b4d554046a3ed44f41be1a338
Autor:
Jonghui Kim, Karla Hegener, Claudia Hagedorn, Kaschin Jamal Jameel, Daniel Weidinger, Inga Marte Charlott Seuthe, Sabine Eichhorn, Florian Kreppel, Jürgen Knobloch, Jonas Jae-Hyun Park
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6383 (2023)
Epithelial cells may play an important role in the pathologic process of chronic rhinosinusitis with nasal polyps. Therefore, providing epithelial cells from a biobank could greatly contribute to further research. In the present work, the isolation o
Externí odkaz:
https://doaj.org/article/c7756c57a1ec49e38c5286d1cf97f9aa
Autor:
Florian Kreppel, Claudia Hagedorn
Publikováno v:
Genes, Vol 13, Iss 10, p 1872 (2022)
The efficient delivery and stable transgene expression are critical for applications in gene therapy. While carefully selected and engineered viral vectors allowed for remarkable clinical successes, they still bear significant safety risks. Thus, non
Externí odkaz:
https://doaj.org/article/8758bf8cfa8e473695a8dac45b2b567b
Autor:
Jonas Scholz, Patrick Philipp Weil, Daniel Pembaur, Georgia Koukou, Malik Aydin, Dorota Hauert, Jan Postberg, Florian Kreppel, Claudia Hagedorn
Publikováno v:
Viruses, Vol 14, Iss 9, p 1952 (2022)
Only two decades after discovering miRNAs, our understanding of the functional effects of deregulated miRNAs in the development of diseases, particularly cancer, has been rapidly evolving. These observations and functional studies provide the basis f
Externí odkaz:
https://doaj.org/article/af850ea691694d4a9e4877f85123e3d1
Autor:
Kingsley Gideon Kumashie, Marcin Cebula, Claudia Hagedorn, Florian Kreppel, Marina C. Pils, Friedrich Koch-Nolte, Björn Rissiek, Dagmar Wirth
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Chronic hepatotropic viral infections are characterized by exhausted CD8+ T cells in the presence of cognate antigen in the liver. The impairment of T cell response limits the control of chronic hepatotropic viruses. Immune-modulatory strategies are
Externí odkaz:
https://doaj.org/article/0ed1772624a74cefa35f6a86e82ebbd3
Autor:
Malik Aydin, Ella A. Naumova, Soeren Lutz, Almut Meyer-Bahlburg, Wolfgang H. Arnold, Florian Kreppel, Anja Ehrhardt, Jan Postberg, Stefan Wirth
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
In summer 2017, the World Health Organization published 10 facts on asthma, which is known as a major non-communicable disease of high clinical and scientific importance with currently several hundred million people—with many children among them—
Externí odkaz:
https://doaj.org/article/8218c43784a04a2a8e156635fed393db
Autor:
Filomena Broeskamp, Elizabeth S. M. Edrich, Oskar Knittelfelder, Lisa Neuhaus, Thorsten Meyer, Jonas Heyden, Lukas Habernig, Florian Kreppel, Campbell W. Gourlay, Patrick Rockenfeller
Publikováno v:
Cells, Vol 10, Iss 9, p 2416 (2021)
Autophagy is a cellular recycling program which efficiently reduces the cellular burden of ageing. Autophagy is characterised by nucleation of isolation membranes, which grow in size and further expand to form autophagosomes, engulfing cellular mater
Externí odkaz:
https://doaj.org/article/1a6f54ffecae44a8a599bd8710dcc9dc