Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Florian, Freudenberg"'
Autor:
Alexandra Vogel, Timo Ueberbach, Annett Wilken-Schmitz, Lisa Hahnefeld, Luisa Franck, Marc-Philipp Weyer, Tassilo Jungenitz, Tobias Schmid, Giulia Buchmann, Florian Freudenberg, Ralf P. Brandes, Robert Gurke, Stephan W. Schwarzacher, Gerd Geisslinger, Thomas Mittmann, Irmgard Tegeder
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-24 (2023)
Abstract Background Pain in early life may impact on development and risk of chronic pain. We developed an optogenetic Cre/loxP mouse model of “early-life-pain” (ELP) using mice with transgenic expression of channelrhodopsin-2 (ChR2) under contro
Externí odkaz:
https://doaj.org/article/1360257bc91b435c8db71bf01203a661
Autor:
Li-Li Li, Florence M. Klein, Lorenzo Li Greci, Arkadiusz Popinigis, Florian Freudenberg, Michael J. Courtney
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Cellular optogenetics applications are limited by difficulties in quantification and blue light toxicity. Here the authors design LOV2-based switches that use resonance energy transfer to overcome these concerns.
Externí odkaz:
https://doaj.org/article/fdc3c80f636643a7b83e6386b06a2535
Autor:
Florian Freudenberg, Esin Candemir, Xufeng Chen, Li-Li Li, Dilhan Esen-Sehir, Nicole Schenk, Makoto Kinoshita, Lena Grünewald, Veronika Frerichs, Nikolai Fattakhov, Jessica Manchen, Solmaz Bikas, Anita Kumar, Aet OLeary, David A. Slattery, Jakob von Engelhardt, Michael J. Courtney, Andreas Reif
Publikováno v:
EBioMedicine, Vol 71, Iss , Pp 103565- (2021)
Background: Nitric oxide synthase 1 adaptor protein (NOS1AP; previously named CAPON) is linked to the glutamatergic postsynaptic density through interaction with neuronal nitric oxide synthase (nNOS). NOS1AP and its interaction with nNOS have been as
Externí odkaz:
https://doaj.org/article/38cf142210fc4beeb6a89b3aa32c23c7
Autor:
Rhiannon V. McNeill, Christopher Kehrwald, Murielle Brum, Katrin Knopf, Nathalie Brunkhorst-Kanaan, Semra Etyemez, Carolin Koreny, Robert A. Bittner, Florian Freudenberg, Sabine Herterich, Andreas Reif, Sarah Kittel-Schneider
Publikováno v:
Brain, Behavior, and Immunity
Nitric oxide (NO) signalling has been implicated in the pathogenesis of several mental illnesses; however, its specific contribution remains unclear. We investigated whether peripheral NO concentration is associated with specific diagnoses, and wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f50101748b22442887d3b4053eeefc7
https://doi.org/10.1016/j.bbi.2022.01.006
https://doi.org/10.1016/j.bbi.2022.01.006
Autor:
Alexandra Vogel, Timo Ueberbach, Annett Wilken-Schmitz, Lisa Hahnefeld, Luisa Franck, Marc-Philipp Weyer, Tassilo Jungenitz, Tobias Schmid, Giulia Buchmann, Florian Freudenberg, Ralf P. Brandes, Robert Gurke, Stephan W. Schwarzacher, Gerd Geisslinger, Thomas Mittmann, Irmgard Tegeder
Pain in early life may affect cortical development and risk of chronic pain. We developed an optogenetic Cre/loxP mouse model of "early-life-pain" (ELP) using mice with transgenic expression of channelrhodopsin-2 (ChR2) under control of the Advillin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d383ead2e7cc3c8cbbaada7fedd124
https://doi.org/10.21203/rs.3.rs-2560826/v1
https://doi.org/10.21203/rs.3.rs-2560826/v1
Autor:
Heike Althen, Kim Falk, Andreas Reif, Robert A. Bittner, Michael M. Plichta, Florian Freudenberg
Publikováno v:
Acta Neuropsychiatrica
Objective:Sensorimotor gating is experimentally operationalized by the prepulse inhibition (PPI) of the startle response (SR). Previous studies suggest high test-retest reliability of PPI and potential correlation with working memory (WM). Here, we a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a619b9a74bea4c0884e81a998b1a3ea
https://pubmed.ncbi.nlm.nih.gov/35959694
https://pubmed.ncbi.nlm.nih.gov/35959694
Autor:
Esin Candemir, Nikolai Fattakhov, Aet O. Leary, David A. Slattery, Michael J. Courtney, Andreas Reif, Florian Freudenberg
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 67
The neuronal isoform of nitric oxide synthase (nNOS) and its interacting protein NOS1AP have been linked to several mental disorders including schizophrenia and depression. An increase in the interaction between nNOS and NOS1AP in the frontal cortex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98bc9b6276f5996a5b158be215bfd939
https://pubmed.ncbi.nlm.nih.gov/36513018
https://pubmed.ncbi.nlm.nih.gov/36513018
Autor:
Dilhan Esen-Sehir, Juliane Kopf, Sandra Hägele, Michael M. Plichta, Andreas Reif, Florian Freudenberg
Publikováno v:
Pharmacopsychiatry. 55(5)
Introduction The variants of the gene for nitric oxide synthase 1 adaptor protein (NOS1AP) are associated with schizophrenia and cardiovascular deficits involving corrected QT (QTc) interval prolongation. Here, we investigated a possible pharmacogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5470b13697e3e270df182f60bece9c4a
https://pubmed.ncbi.nlm.nih.gov/35732169
https://pubmed.ncbi.nlm.nih.gov/35732169
Autor:
Florian Freudenberg, Verena Marx, Volker Mack, Liliana E. Layer, Matthias Klugmann, Peter H. Seeburg, Rolf Sprengel, Tansu Celikel
Publikováno v:
Neurobiology of Disease, Vol 52, Iss , Pp 160-167 (2013)
Glutamate receptor dependent synaptic plasticity plays an important role in the pathophysiology of depression. Hippocampal samples from clinically depressed patients display reduced mRNA levels for GluA1, a major subunit of AMPA receptors. Moreover,
Externí odkaz:
https://doaj.org/article/78b5cc7801db48129ad97384a88b8f67
Autor:
Aet O’Leary, Noèlia Fernàndez-Castillo, Gabriela Gan, Yunbo Yang, Anna Y. Yotova, Thorsten M. Kranz, Lena Grünewald, Florian Freudenberg, Ester Antón-Galindo, Judit Cabana-Domínguez, Anais Harneit, Janina I. Schweiger, Kristina Schwarz, Ren Ma, Junfang Chen, Emanuel Schwarz, Marcella Rietschel, Heike Tost, Andreas Meyer-Lindenberg, Christiane A. Pané-Farré, Tilo Kircher, Alfons O. Hamm, Demian Burguera, Nina Roth Mota, Barbara Franke, Susann Schweiger, Jennifer Winter, Andreas Heinz, Susanne Erk, Nina Romanczuk-Seiferth, Henrik Walter, Andreas Ströhle, Lydia Fehm, Thomas Fydrich, Ulrike Lueken, Heike Weber, Thomas Lang, Alexander L. Gerlach, Markus M. Nöthen, Georg W. Alpers, Volker Arolt, Stephanie Witt, Jan Richter, Benjamin Straube, Bru Cormand, David A. Slattery, Andreas Reif
Publikováno v:
Mol Psychiatry
Common variation in the gene encoding the neuron-specific RNA splicing factor RNA Binding Fox-1 Homolog 1 (RBFOX1) has been identified as a risk factor for several psychiatric conditions, and rare genetic variants have been found causal for autism sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97658d2ed857991b8db598d104859a1a