Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Florian, Eckhardt"'
Autor:
Rene Cortese, Jörn Lewin, Liselotte Bäckdahl, Manuel Krispin, Reinhold Wasserkort, Florian Eckhardt, Stephan Beck
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26002 (2011)
Cellular differentiation involves widespread epigenetic reprogramming, including modulation of DNA methylation patterns. Using Differential Methylation Hybridization (DMH) in combination with a custom DMH array containing 51,243 features covering mor
Externí odkaz:
https://doaj.org/article/ca5f1967b3e042e6856813298b5b5d96
Publikováno v:
Personalized medicine. 2(4)
Over the last few decades, a wealth of treatment options have become available for breast cancer. To specifically direct those therapies to patients with the highest need who will receive the greatest benefit, biomarkers are urgently needed. Two spec
Autor:
Andreas Thiel, Florian Eckhardt, Yu Qian, Jun Dong, Laura Maggi, Francesco Annunziato, Lorenzo Cosmi, Soheila Rezai, Manfred Gossen, Andreas Radbruch, Joachim Sieper, Peihua Wu, Tobias Alexander, Anna Okhrimenko, Claudia Ivascu, Jun Li, Hyun-Dong Chang
Publikováno v:
European Journal of Immunology. 43:793-804
Cytokine memory for IFN-γ production by effector/memory Th1 cells plays a key role in both protective and pathological immune responses. To understand the epigenetic mechanism determining the ontogeny of effector/memory Th1 cells characterized by st
Autor:
Marlis Herberth, Florian Eckhardt, Peri Tate, Liselotte Bäckdahl, Lia S. Campos, Stephan Beck, Gareth A. Wilson, Rene Cortese
Publikováno v:
Epigenetics. 4:248-254
DNA methylation is an important epigenetic mark that is involved in the regulation of many cellular processes such as gene expression, genomic imprinting and silencing of repetitive elements. Because of their ability to cause and capture phenotypic p
Autor:
Rene Cortese, John Attwood, Jane Rogers, Christoph Koenig, Kevin L. Howe, Roger Horton, Florian Eckhardt, Joern Lewin, David K. Jackson, Roger Pettett, David Niblett, Thomas A. Down, Robert L. Davies, Carolina Haefliger, Stephan Beck, Jan Kunde, Kurt Berlin, Tony West, Matthias Burger, Stefanie Seemann, Alex Olek, Thomas J. Otto, Christian Thompson, Vardhman K. Rakyan, Tony Cox, John Burton, Jennifer Liddle
Publikováno v:
Nature genetics
DNA methylation constitutes the most stable type of epigenetic modifications modulating the transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report high-resolution methylation reference profiles of human chromosomes
Publikováno v:
Expert Review of Molecular Diagnostics. 4:609-618
Deciphering the information encoded in the human genome is key for the further understanding of human biology, physiology and evolution. With the draft sequence of the human genome completed, elucidation of the epigenetic information layer of the hum
Autor:
Andreas Meyerhans, Florian Eckhardt
Publikováno v:
NeuroReport. 9:3975-3979
The semaphorin/collapsin family of proteins comprises molecules thought to be important for the guidance of growing axons. All members of this family, which includes both secreted and cell-surface molecules, share a conserved domain of approximately
Autor:
Enzo Calautti, Mark C. Fishman, Florian Eckhardt, Ikuo Nishimoto, Kazuyoshi Yonezawa, Oded Behar
Publikováno v:
Molecular and Cellular Neuroscience. 9:409-419
The semaphorins/collapsins constitute a family of genes unified by the presence of a "semaphorin domain" which has been conserved through metazoan evolution. The semaphorin family comprises both secreted and transmembrane molecules and is thought to
Autor:
Jun, Dong, Hyun-Dong, Chang, Claudia, Ivascu, Yu, Qian, Soheila, Rezai, Anna, Okhrimenko, Lorenzo, Cosmi, Laura, Maggi, Florian, Eckhardt, Peihua, Wu, Joachim, Sieper, Tobias, Alexander, Francesco, Annunziato, Manfred, Gossen, Jun, Li, Andreas, Radbruch, Andreas, Thiel
Publikováno v:
European journal of immunology. 43(3)
Cytokine memory for IFN-γ production by effector/memory Th1 cells plays a key role in both protective and pathological immune responses. To understand the epigenetic mechanism determining the ontogeny of effector/memory Th1 cells characterized by st
Autor:
Florian Eckhardt, Ivana Türbachova, Paul Gardina, Alexander Hellwag, Sven Olek, Ulrich Hoffmüller, Kurt Berlin, Udo Baron
Publikováno v:
Epigenetics. 1(1)
Cell therapeutic approaches currently lack definitive quality control measures which guarantee safety in clinical applications and create consistent standards for regulatory approval. These approaches rely on isolation, purification and possibly ex v