Zobrazeno 1 - 10
of 280
pro vyhledávání: '"Florentine S"'
Autor:
Florentine S. Hilbers, Coralie Poncet, Konstantinos Tryfonidis, Giuseppe Viale, Suzette Delaloge, Jean-Yves Pierga, Etienne G. C. Brain, Isabel T. Rubio, Alastair M. Thompson, Emiel J. T. Rutgers, Martine J. Piccart, Laura J. van ’t Veer, Fatima Cardoso
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Small, hormone receptor-positive (HR+), HER2-negative (HER2-), lymph node-negative breast cancers are associated with relatively low rates of disease recurrence and have therefore been underrepresented in clinical trials assessing the effect
Externí odkaz:
https://doaj.org/article/d632b4b675464734a9b0c41dc7dee912
Autor:
Jörg Hänze, Lilly M. Mengen, Marco Mernberger, Dinesh Kumar Tiwari, Thomas Plagge, Andrea Nist, Florentine S. B. Subtil, Ulrike Theiss, Fabian Eberle, Katrin Roth, Matthias Lauth, Rainer Hofmann, Rita Engenhart-Cabillic, Thorsten Stiewe, Axel Hegele
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Radiotherapy is essential in the treatment of prostate cancer. An alternative to conventional photon radiotherapy is the application of carbon ions, which provide a superior intratumoral dose distribution and less induced damage t
Externí odkaz:
https://doaj.org/article/fad8adc82b6c4138974260b87cd5e500
Autor:
Sonja Vliek, Florentine S. Hilbers, Erik van Werkhoven, Ingrid Mandjes, Rob Kessels, Sieta Kleiterp, Esther H. Lips, Lennart Mulder, Mutamba T. Kayembe, Claudette E. Loo, Nicola S. Russell, Marie-Jeanne T. F. D. Vrancken Peeters, Marjo J. Holtkamp, Margaret Schot, Joke W. Baars, Aafke H. Honkoop, Annelie J. E. Vulink, Alex L. T. Imholz, Suzan Vrijaldenhoven, Franchette W. P. J. van den Berkmortel, Jetske M. Meerum Terwogt, Jolanda G. Schrama, Philomeen Kuijer, Judith R. Kroep, Annemieke van der Padt-Pruijsten, Jelle Wesseling, Gabe S. Sonke, Kenneth G. A. Gilhuijs, Agnes Jager, Petra Nederlof, Sabine C. Linn
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Exploratory analyses of high-dose alkylating chemotherapy trials have suggested that BRCA1 or BRCA2-pathway altered (BRCA-altered) breast cancer might be particularly sensitive to this type of treatment. In this study, patients with BRCA-alt
Externí odkaz:
https://doaj.org/article/8df2c3c9b54e4fdaa94ca1a2ca82efc6
Autor:
Dinesh Kumar Tiwari, Ricarda Hannen, Kristian Unger, Sibylla Kohl, Julia Heß, Kirsten Lauber, Florentine S. B. Subtil, Ekkehard Dikomey, Rita Engenhart-Cabillic, Ulrike Schötz
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundTreatment of locally advanced HPV-negative head and neck squamous cell carcinoma (HNSCC) with photon radiation is the standard of care but shows only moderate success. Alterations in response toward DNA DSB repair, apoptosis, and senescence
Externí odkaz:
https://doaj.org/article/e90b8674e62f42a5a9f5a74d2c061c2c
Autor:
Francesca Poggio, Lucia Del Mastro, Florentine S Hilbers, Saranya Chumsri, Noam F Pondé, Dominique Agbor-Tarh, Otto Metzger-Filho, Larissa A Korde, Olena Werner, Volker Moebus, Alvaro Moreno-Aspitia, Martine J Piccart
Publikováno v:
ESMO Open, Vol 5, Iss 6 (2020)
Background In HER2-positive breast cancer, time elapsed between completion of (neo)adjuvant trastuzumab and diagnosis of metastatic disease (‘trastuzumab-free interval’, TFI) is crucial to choose the optimal first-line treatment. Nevertheless, th
Externí odkaz:
https://doaj.org/article/1527dc5a1b994a6ca8d07abfc732dc49
Autor:
Serena Di Cosimo, Valentina Appierto, Sara Pizzamiglio, Marco Silvestri, José Baselga, Martine Piccart, Jens Huober, Miguel Izquierdo, Lorena de la Pena, Florentine S. Hilbers, Evandro de Azambuja, Michael Untch, Lajos Pusztai, Kathleen Pritchard, Paolo Nuciforo, Anne Vincent-Salomon, Fraser Symmans, Giovanni Apolone, Filippo G. de Braud, Marilena V. Iorio, Paolo Verderio, Maria Grazia Daidone
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1386 (2020)
Circulating microRNA (ct-miRNAs) are able to identify patients with differential response to HER2-targeted therapy. However, their dynamics are largely unknown. We assessed 752 miRNAs from 52 NeoALTTO patients with plasma pairs prior and two weeks af
Externí odkaz:
https://doaj.org/article/c17c91ee4a3944f1a25b0f0df0cf277b
Autor:
Florentine S Hilbers, Caro M Meijers, Jeroen F J Laros, Michiel van Galen, Nicoline Hoogerbrugge, Hans F A Vasen, Petra M Nederlof, Juul T Wijnen, Christi J van Asperen, Peter Devilee
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55734 (2013)
The bulk of familial breast cancer risk (∼70%) cannot be explained by mutations in the known predisposition genes, primarily BRCA1 and BRCA2. Underlying genetic heterogeneity in these cases is the probable explanation for the failure of all attempt
Externí odkaz:
https://doaj.org/article/4a061793332a4654a5c0029d77135335
Autor:
Francisco Javier Gracia-Aznarez, Victoria Fernandez, Guillermo Pita, Paolo Peterlongo, Orlando Dominguez, Miguel de la Hoya, Mercedes Duran, Ana Osorio, Leticia Moreno, Anna Gonzalez-Neira, Juan Manuel Rosa-Rosa, Olga Sinilnikova, Sylvie Mazoyer, John Hopper, Conchi Lazaro, Melissa Southey, Fabrice Odefrey, Siranoush Manoukian, Irene Catucci, Trinidad Caldes, Henry T Lynch, Florentine S M Hilbers, Christi J van Asperen, Hans F A Vasen, David Goldgar, Paolo Radice, Peter Devilee, Javier Benitez
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55681 (2013)
The identification of the two most prevalent susceptibility genes in breast cancer, BRCA1 and BRCA2, was the beginning of a sustained effort to uncover new genes explaining the missing heritability in this disease. Today, additional high, moderate an
Externí odkaz:
https://doaj.org/article/8d2de2f1da8b4285a404e7b32bbfc2f0
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