Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Florentina Lupașcu"'
Autor:
Nela Bibire, Florentina Lupașcu, Sylvain Routier, Frédéric Buron, Sandra Constantin, Alexandru Sava, Alin Viorel Focșa, Lenuţa Profire, Alina Panainte
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7079, p 7079 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences
Volume 22
Issue 13
Starting from indomethacin (IND), one of the most prescribed non-steroidal anti-inflammatory drugs (NSAIDs), new nitric oxide-releasing indomethacin derivatives with 1,3,4-oxadiazole-2-thiol scaffold (NO-IND-OXDs, 8a–p) have been developed as a saf
Autor:
Lenuța Profire, Anca Roxana Petrovici, Ioana Vasincu, Maria Apotrosoaei, Mariana Pinteala, Narcisa Marangoci, Florentina Lupașcu
Publikováno v:
The 1st International Electronic Conference on Pharmaceutics.
(1) Background: Cyclodextrins are used in various areas due to their ability to form inclusion complexes and to modify some properties of the guest molecule. The characteristics that can be improved are related to the solubility of poorly water-solub
Autor:
Frédéric Buron, Sylvain Routier, Alexandru Sava, Sandra Constantin, Maria Apotrosoaei, Lenuţa Profire, Florentina Lupașcu, Cristina Tuchilus, Luminița Confederat, Marta Teodora Constantin, Ioana Vasincu
Publikováno v:
Materials, Vol 12, Iss 4, p 558 (2019)
Materials
Volume 12
Issue 4
Materials
Volume 12
Issue 4
In the past many research studies have focused on the thiazolidine-4-one scaffold, due to the important biological effects associated with its heterocycle. This scaffold is present in the structure of many synthetic compounds, which showed significan
Autor:
Ioana Mirela Vasincu, Maria Apotrosoaei, Florentina Lupascu, Andreea-Teodora Iacob, Simona-Eliza Giusca, Irina-Draga Caruntu, Narcisa-Laura Marangoci, Anca Roxana Petrovici, Gabriela Dumitrita Stanciu, Bogdan-Ionel Tamba, Bianca-Stefania Profire, Alin-Viorel Focsa, Mariana Pinteala, Lenuta Profire
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2492 (2023)
Generally, NSAIDs are weakly soluble in water and contain both hydrophilic and hydrophobic groups. One of the most widely used NSAIDs is ibuprofen, which has a poor solubility and high permeability profile. By creating dynamic, non-covalent, water-so
Externí odkaz:
https://doaj.org/article/41f03abcc9ed449582e6c7ad6a7fd350
Autor:
Simona-Maria Tatarusanu, Alexandru Sava, Bianca-Stefania Profire, Tudor Pinteala, Alexandra Jitareanu, Andreea-Teodora Iacob, Florentina Lupascu, Natalia Simionescu, Irina Rosca, Lenuta Profire
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 975 (2023)
Wound management represents a continuous challenge for health systems worldwide, considering the growing incidence of wound-related comorbidities, such as diabetes, high blood pressure, obesity, and autoimmune diseases. In this context, hydrogels are
Externí odkaz:
https://doaj.org/article/a67b1af20f1f450189deaf8f5a1d6d20
Autor:
Dragos Pieptu, Ramona Florina Moraru, Valentin Nastasa, Mihai Mares, Cornelia Vasile, Florentina Lupascu, Oana Maria Dragostin, Lenuta Profire
Publikováno v:
Molecules, Vol 18, Iss 4, Pp 4140-4157 (2013)
New series of N-(arylidene)hydrazinoacetyl sulfonamides 4a1–6, 4b1–6 and N-(4-aryl-3-chloro-2-oxoazetidin-1-yl)aminoacetyl sulfonamides 5a1–6, 5b1–6 were synthesized. The structures of the new derivatives was confirmed using spectral methods
Externí odkaz:
https://doaj.org/article/a6192f0a9c794724ae5c535d57cbc228