Výsledky vyhledávání - "Florent Olivon"

Akademický článek

Synthesis and Anti-Leishmanial Properties of Quinolones Derived from Zanthosimuline

Autor: Gwenaëlle Jézéquel, Laura Nogueira de Faria Cardoso, Florent Olivon, Indira Dennemont, Cécile Apel, Marc Litaudon, Fanny Roussi, Sébastien Pomel, Sandy Desrat

Publikováno v: Molecules, Vol 27, Iss 22, p 7892 (2022)

Quinoline derivatives and especially quinolones are considered as privileged structures in medicinal chemistry and are often associated with various biological properties. We recently isolated a series of original monoterpenyl quinolones from the bar

Externí odkaz: https://doaj.org/article/9740a22337734f6582856a044efcb85f

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Antiviral Effect of

Autor: Fenia D, Ramiharimanana, Juliano G, Haddad, Maminiaina A, Andrianavalonirina, Cécile, Apel, Florent, Olivon, Nicolas, Diotel, Philippe, Desprès, Voahangy Vestalys, Ramanandraibe, Chaker, El Kalamouni

Publikováno v: Pharmaceuticals (Basel, Switzerland). 15(12)

Dengue and Zika viruses are identified as the most medically important arthropod-borne viral pathogens. Over the past 20 years, the global dengue incidence has dramatically increased with epidemics of severe dengue where the case fatality rate can re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1bc79c98766f723743f392b1d340772
https://pubmed.ncbi.nlm.nih.gov/36558951

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Antiviral Compounds from Codiaeum peltatum Targeted by a Multi-informative Molecular Networks Approach

Autor: Gwendal Grelier, Jean-Claude Guillemot, Johan Neyts, Leen Delang, Cécile Apel, Marc Litaudon, Florent Olivon, David Touboul, Cécilia Eydoux, Simon Remy, Fanny Roussi

Publikováno v: Journal of Natural Products
Journal of Natural Products, American Chemical Society, 2019, 82 (2), pp.330-340. ⟨10.1021/acs.jnatprod.8b00800⟩
Journal of Natural Products, 2019, 82 (2), pp.330-340. ⟨10.1021/acs.jnatprod.8b00800⟩

From a set of 292 Euphorbiaceae extracts, the use of a molecular networking (MN)-based prioritization approach highlighted three clusters (MN1-3) depicting ions from the bark extract of Codiaeum peltatum. Based on their putative antiviral potential a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed1651c6f73327700c11f509551d13e
https://doi.org/10.1021/acs.jnatprod.8b00800

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Isolation of Picrotoxanes from Austrobuxus carunculatus Using Taxonomy-Based Molecular Networking

Autor: David Touboul, Pascal Retailleau, Cécile Apel, Florent Olivon, Sandy Desrat, Fanny Roussi, Marc Litaudon

Publikováno v: Journal of Natural Products
Journal of Natural Products, American Chemical Society, 2020, 83 (10), pp.3069-3079. ⟨10.1021/acs.jnatprod.0c00636⟩

A unique collection of 292 extracts from 107 New Caledonian Euphorbiaceae species sensu lato was profiled by LC-MS2 and the metabolite content organized by molecular networking. Based on the assumption that taxon-specific molecules are more likely to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adc5fb7a40cae5976431b782755bea0
https://hal.archives-ouvertes.fr/hal-02992365/document

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Isolation of Picrotoxanes from

Autor: Florent, Olivon, Pascal, Retailleau, Sandy, Desrat, David, Touboul, Fanny, Roussi, Cécile, Apel, Marc, Litaudon

Publikováno v: Journal of natural products. 83(10)

A unique collection of 292 extracts from 107 New Caledonian Euphorbiaceae species

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f68771c5d648acc60178824271c09aad
https://pubmed.ncbi.nlm.nih.gov/33016067

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MetGem Software for the Generation of Molecular Networks Based on the t-SNE Algorithm

Autor: Nicolas Elie, Fanny Roussi, Gwendal Grelier, Marc Litaudon, David Touboul, Florent Olivon

Publikováno v: Analytical Chemistry
Analytical Chemistry, American Chemical Society, 2018, 90 (23), pp.13900-13908. ⟨10.1021/acs.analchem.8b03099⟩

Molecular networking (MN) is becoming a standard bioinformatics tool in the metabolomic community. Its paradigm is based on the observation that compounds with a high degree of chemical similarity share comparable MS2 fragmentation pathways. To affor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4584173f720adb518fda58e6ab66b6c3
https://doi.org/10.1021/acs.analchem.8b03099

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Development of an innovative molecular networking-based approach for the discovery and targeted isolation of new bioactive metabolites from higher plants

Autor: Marc Litaudon, David Touboul, Florent Olivon, Simon Remy

Publikováno v: 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61fba21b307fe032fdaf3d85fabdeb93
https://doi.org/10.1055/s-0039-3399695

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Feature-based molecular networking and network annotation propagation applied to natural antiviral compound research from tropical Euphorbiaceae

Autor: David Touboul, Simon Remy, Florent Olivon, Marc Litaudon, D Solis

Publikováno v: 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::822452eb92d1ef99ca113aa0e49d8fbc
https://doi.org/10.1055/s-0039-3399652

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Optimized experimental workflow for tandem mass spectrometry molecular networking in metabolomics

Autor: Fanny Roussi, Marc Litaudon, David Touboul, Florent Olivon

Publikováno v: Analytical and Bioanalytical Chemistry. 409:5767-5778

New omics sciences generate massive amounts of data, requiring to be sorted, curated, and statistically analyzed by dedicated software. Data-dependent acquisition mode including inclusion and exclusion rules for tandem mass spectrometry is routinely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb245f5bf2e924cadc7cc0412c66333
https://doi.org/10.1007/s00216-017-0523-3

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