An Active Follow-up Strategy for Serological Suspects of Human African Trypanosomiasis with Negative Parasitology Set up by a Health Zone Team in the Democratic Republic of Congo

Autor: Matthieu Nkieri, Florent Mbo, Papy Kavunga, Pathou Nganzobo, Titus Mafolo, Chalet Selego, Eric Mwamba Miaka

Publikováno v: Tropical Medicine and Infectious Disease, Vol 5, Iss 2, p 53 (2020)

Background: The World Health Organization aims for the elimination of Human African Trypanosomiasis (HAT) as a public health problem by 2020 and for full elimination (absence of new cases) by 2030. One of strategies to achieve this is the active foll

Externí odkaz: https://doaj.org/article/1c776104f3d94ef395bbe9a62a0fa81c

Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial.

Autor: Gabriele Pohlig, Sonja C Bernhard, Johannes Blum, Christian Burri, Alain Mpanya, Jean-Pierre Fina Lubaki, Alfred Mpoo Mpoto, Blaise Fungula Munungu, Patrick Mangoni N'tombe, Gratias Kambau Manesa Deo, Pierre Nsele Mutantu, Florent Mbo Kuikumbi, Alain Fukinsia Mintwo, Augustin Kayeye Munungi, Amadeu Dala, Stephen Macharia, Constantin Miaka Mia Bilenge, Victor Kande Betu Ku Mesu, Jose Ramon Franco, Ndinga Dieyi Dituvanga, Richard R Tidwell, Carol A Olson

Publikováno v: PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004363 (2016)

BACKGROUND:Sleeping sickness (human African trypanosomiasis [HAT]) is a neglected tropical disease with limited treatment options that currently require parenteral administration. In previous studies, orally administered pafuramidine was well tolerat

Externí odkaz: https://doaj.org/article/54ad4e12d63a49d885737d44dd4774db

An Active Follow-up Strategy for Serological Suspects of Human African Trypanosomiasis with Negative Parasitology Set up by a Health Zone Team in the Democratic Republic of Congo

Autor: Eric Mwamba Miaka, Titus Mafolo, Matthieu Nkieri, Pathou Nganzobo, Chalet Selego, Papy Kavunga, Florent Mbo

Publikováno v: Tropical Medicine and Infectious Disease; Volume 5; Issue 2; Pages: 53
Tropical Medicine and Infectious Disease, Vol 5, Iss 53, p 53 (2020)
Tropical Medicine and Infectious Disease

Background: The World Health Organization aims for the elimination of Human African Trypanosomiasis (HAT) as a public health problem by 2020 and for full elimination (absence of new cases) by 2030. One of strategies to achieve this is the active foll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6b1bbfb97ac8ea34edad6bbc185a49

Efficacy and safety of pafuramidine versus pentamidine maleate for treatment of first stage sleeping sickness in a randomized, comparator-controlled, international phase 3 clinical trial

Autor: Christian Burri, Patrick Mangoni N’tombe, Richard R. Tidwell, Carol A. Olson, Pierre Nsele Mutantu, José R. Franco, Alain Fukinsia Mintwo, Johannes Blum, Amadeu Dala, Alfred Mpoo Mpoto, Constantin Miaka Mia Bilenge, Stephen Macharia, Augustin Kayeye Munungi, Gabriele Pohlig, Florent Mbo Kuikumbi, Alain Mpanya, Gratias Kambau Manesa Deo, Ndinga Dieyi Dituvanga, Sonja C. Bernhard, Victor Kande Betu Ku Mesu, Jean Pierre Fina Lubaki, Blaise Fungula Munungu

Publikováno v: PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004363 (2016)
PLoS Neglected Tropical Diseases

Background Sleeping sickness (human African trypanosomiasis [HAT]) is a neglected tropical disease with limited treatment options that currently require parenteral administration. In previous studies, orally administered pafuramidine was well tolerat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e60a4421a5baa6e621690fefdd5db0

Cardiac Alterations in Human African Trypanosomiasis (T.b. gambiense) with Respect to the Disease Stage and Antiparasitic Treatment

Autor: Patrick Mangoni, Alain Mpanya, Carol A. Olson, Amadeo Dala, Michael J. Zellweger, José R. Franco, Florent Mbo, Christian Burri, Gabriele Pohlig, Leon Kazumba, Johannes Blum, Kambau Deo, Christoph Hatz, Caecilia Schmid, Blaise Fungula

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 3, Iss 2, p e383 (2009)

Background In Human African Trypanosomiasis, neurological symptoms dominate and cardiac involvement has been suggested. Because of increasing resistance to the available drugs for HAT, new compounds are desperately needed. Evaluation of cardiotoxicit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bd8bd07f4e4e5d4fda45f3dbdc6dd6
http://europepmc.org/articles/PMC2640099