Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Florent Dufour"'
Autor:
Jing Liu, Daniela Ottaviani, Meriem Sefta, Céline Desbrousses, Elodie Chapeaublanc, Rosario Aschero, Nanor Sirab, Fabiana Lubieniecki, Gabriela Lamas, Laurie Tonon, Catherine Dehainault, Clément Hua, Paul Fréneaux, Sacha Reichman, Narjesse Karboul, Anne Biton, Liliana Mirabal-Ortega, Magalie Larcher, Céline Brulard, Sandrine Arrufat, André Nicolas, Nabila Elarouci, Tatiana Popova, Fariba Némati, Didier Decaudin, David Gentien, Sylvain Baulande, Odette Mariani, Florent Dufour, Sylvain Guibert, Céline Vallot, Livia Lumbroso-Le Rouic, Alexandre Matet, Laurence Desjardins, Guillem Pascual-Pasto, Mariona Suñol, Jaume Catala-Mora, Genoveva Correa Llano, Jérôme Couturier, Emmanuel Barillot, Paula Schaiquevich, Marion Gauthier-Villars, Dominique Stoppa-Lyonnet, Lisa Golmard, Claude Houdayer, Hervé Brisse, Isabelle Bernard-Pierrot, Eric Letouzé, Alain Viari, Simon Saule, Xavier Sastre-Garau, François Doz, Angel M. Carcaboso, Nathalie Cassoux, Celio Pouponnot, Olivier Goureau, Guillermo Chantada, Aurélien de Reyniès, Isabelle Aerts, François Radvanyi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Retinoblastoma is the most frequent intraocular paediatric malignancy whose molecular basis remains poorly understood. Here, the authors perform multi-omic analysis and identify two subtypes; one in a cone differentiated state and one more aggressive
Externí odkaz:
https://doaj.org/article/92fda6743ce64715a5b5d4c807ca5ced
Autor:
Hervé Lang, Claire Béraud, Luc Cabel, Jacqueline Fontugne, Myriam Lassalle, Clémentine Krucker, Florent Dufour, Clarice S. Groeneveld, Victoria Dixon, Xiangyu Meng, Aurélie Kamoun, Elodie Chapeaublanc, Aurélien De Reynies, Xavier Gamé, Pascal Rischmann, Ivan Bieche, Julien Masliah-Planchon, Romane Beaurepere, Yves Allory, Véronique Lindner, Yolande Misseri, François Radvanyi, Philippe Lluel, Isabelle Bernard-Pierrot, Thierry Massfelder
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMuscle-invasive bladder cancer (MIBC) and upper urinary tract urothelial carcinoma (UTUC) are molecularly heterogeneous. Despite chemotherapies, immunotherapies, or anti-fibroblast growth factor receptor (FGFR) treatments, these tumors are
Externí odkaz:
https://doaj.org/article/530d7616638a4e26a742ecd5e89e062d
Autor:
Linda Silina, Florent Dufour, Audrey Rapinat, Cécile Reyes, David Gentien, Fatlinda Maksut, François Radvanyi, Pierre Verrelle, Isabelle Bernard-Pierrot, Frédérique Mégnin-Chanet
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8671 (2022)
Bladder cancer is a common cancer; it is the tenth most common cancer in the world. Around one fourth of all diagnosed patients have muscle-invasive bladder cancer (MIBC), characterized by advanced tumors and which remains a lethal disease. The stand
Externí odkaz:
https://doaj.org/article/af89ec92bec648b3ac36587c58a221d6
Autor:
Natacha Rochel, Clémentine Krucker, Laure Coutos-Thévenot, Judit Osz, Ruiyun Zhang, Elodie Guyon, Wayne Zita, Séverin Vanthong, Oscar Alba Hernandez, Maxime Bourguet, Kays Al Badawy, Florent Dufour, Carole Peluso-Iltis, Syrine Heckler-Beji, Annick Dejaegere, Aurélie Kamoun, Aurélien de Reyniès, Yann Neuzillet, Sandra Rebouissou, Claire Béraud, Hervé Lang, Thierry Massfelder, Yves Allory, Sarah Cianférani, Roland H. Stote, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Activation of the PPARγ/RXRα pathway in luminal bladder cancers has mainly been linked to PPARG gene amplifications and activating point mutations in RXRα. Here, the authors identify recurrent PPARγ mutations with similar effects and elucidate th
Externí odkaz:
https://doaj.org/article/5e44a383003c4ce0b87b4a701664d7c3
Autor:
Mélanie Mahe, Florent Dufour, Hélène Neyret‐Kahn, Aura Moreno‐Vega, Claire Beraud, Mingjun Shi, Imene Hamaidi, Virginia Sanchez‐Quiles, Clementine Krucker, Marion Dorland‐Galliot, Elodie Chapeaublanc, Remy Nicolle, Hervé Lang, Celio Pouponnot, Thierry Massfelder, François Radvanyi, Isabelle Bernard‐Pierrot
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 4, Pp n/a-n/a (2018)
Abstract FGFR3 alterations (mutations or translocation) are among the most frequent genetic events in bladder carcinoma. They lead to an aberrant activation of FGFR3 signaling, conferring an oncogenic dependence, which we studied here. We discovered
Externí odkaz:
https://doaj.org/article/1ed43450adb6412f8cc0a5fba9c79f14
Autor:
Hélène Neyret-Kahn, Jacqueline Fontugne, Xiang Yu Meng, Clarice S. Groeneveld, Luc Cabel, Tao Ye, Elodie Guyon, Clémentine Krucker, Florent Dufour, Elodie Chapeaublanc, Audrey Rapinat, Daniel Jeffery, Laura Tanguy, Victoria Dixon, Yann Neuzillet, Thierry Lebret, David Gentien, Irwin Davidson, Yves Allory, Isabelle Bernard-Pierrot, François Radvanyi
Publikováno v:
Oncogene. 42:1524-1542
Muscle-invasive bladder cancer (BLCA) is an aggressive disease. Consensus BLCA transcriptomic subtypes have been proposed, with two major Luminal and Basal subgroups, presenting distinct molecular and clinical characteristics. However, how these dist
Autor:
Ming-Jun Shi, Jacqueline Fontugne, Aura Moreno-Vega, Xiang-Yu Meng, Clarice Groeneveld, Florent Dufour, Aurélie Kamoun, Sia Viborg Lindskrog, Luc Cabel, Clémentine Krucker, Audrey Rapinat, Claire Dunois-Larde, May-Linda Lepage, Elodie Chapeaublanc, Olivier Levrel, Victoria Dixon, Thierry Lebret, Anna Almeida, Aurélien De Reynies, Natacha Rochel, Lars Dyrskjøt, Yves Allory, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
European Urology
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
Background: Bladder cancer (BCa) is more common in men and presents differences in molecular subtypes based on sex. Fibroblast growth factor receptor 3 (FGFR3) mutations are enriched in the luminal papillary muscle-invasive BCa (MIBC) and non-MIBC su
Autor:
Bruno Ségui, Céline Colacios, Olivier Micheau, Nicolas Meyer, Hervé Benoist, Yusuf A. Hannun, Thierry Levade, Nathalie Andrieu-Abadie, Nicole Therville, Sandrine Silvente-Poirot, Philippe Rochaix, Pierre Brousset, Pierre Cordelier, Michel Record, Virginie Garcia, Nilton De França Junior, Andrei A. Constantinescu, Florent Dufour, Christopher J. Clarke, Marie Tosolini, Joëlle Riond, Caroline Imbert, Carine Dufau, Jean Milhès, Thomas Filleron, Julia Gilhodes, Julia Rochotte, Florie Bertrand, Anne Montfort
TCGA dataset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c81cd1a218e4a125f72f89a2e4ff7de
https://doi.org/10.1158/2326-6066.22543099
https://doi.org/10.1158/2326-6066.22543099
Autor:
Bruno Ségui, Céline Colacios, Olivier Micheau, Nicolas Meyer, Hervé Benoist, Yusuf A. Hannun, Thierry Levade, Nathalie Andrieu-Abadie, Nicole Therville, Sandrine Silvente-Poirot, Philippe Rochaix, Pierre Brousset, Pierre Cordelier, Michel Record, Virginie Garcia, Nilton De França Junior, Andrei A. Constantinescu, Florent Dufour, Christopher J. Clarke, Marie Tosolini, Joëlle Riond, Caroline Imbert, Carine Dufau, Jean Milhès, Thomas Filleron, Julia Gilhodes, Julia Rochotte, Florie Bertrand, Anne Montfort
Dysregulation of lipid metabolism affects the behavior of cancer cells, but how this happens is not completely understood. Neutral sphingomyelinase 2 (nSMase2), encoded by SMPD3, catalyzes the breakdown of sphingomyelin to produce the anti-oncometabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a34c1796665d25bb9746c3808542ff0
https://doi.org/10.1158/2326-6066.c.6550135.v1
https://doi.org/10.1158/2326-6066.c.6550135.v1
Autor:
Bruno Ségui, Céline Colacios, Olivier Micheau, Nicolas Meyer, Hervé Benoist, Yusuf A. Hannun, Thierry Levade, Nathalie Andrieu-Abadie, Nicole Therville, Sandrine Silvente-Poirot, Philippe Rochaix, Pierre Brousset, Pierre Cordelier, Michel Record, Virginie Garcia, Nilton De França Junior, Andrei A. Constantinescu, Florent Dufour, Christopher J. Clarke, Marie Tosolini, Joëlle Riond, Caroline Imbert, Carine Dufau, Jean Milhès, Thomas Filleron, Julia Gilhodes, Julia Rochotte, Florie Bertrand, Anne Montfort
This file contains supplementary table 1 and supplementary figures 1-7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3b91cf696875a561979dec6623bcf1
https://doi.org/10.1158/2326-6066.22543093.v1
https://doi.org/10.1158/2326-6066.22543093.v1