Identification and characterization of the Hfq bacterial amyloid region DNA interactions

Autor: Florian Turbant, Omar El Hamoui, David Partouche, Christophe Sandt, Florent Busi, Frank Wien, Véronique Arluison

Publikováno v: BBA Advances, Vol 1, Iss , Pp 100029- (2021)

Nucleic acid amyloid proteins interactions have been observed in the past few years. These interactions often promote protein aggregation. Nevertheless, molecular basis and physiological consequences of these interactions are still poorly understood.

Externí odkaz: https://doaj.org/article/7ce0e048d2cf4331a00540d7f6517ab8

Evaluation of Amyloid Inhibitor Efficiency to Block Bacterial Survival

Autor: Florent, Busi, Florian, Turbant, Jehan, Waeytens, Omar, El Hamoui, Frank, Wien, Véronique, Arluison

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2538

Amyloid inhibitors, such as the green tea compound epigallocatechin gallate EGCG, apomorphine or curlicide, have antibacterial properties. Conversely, antibiotics such as tetracycline derivatives or rifampicin also affect eukaryotic amyloids formatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::36899ddccb8ce7be36109f8707bf9ff3
https://pubmed.ncbi.nlm.nih.gov/35951299

T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide

Autor: Jean-Marie Dupret, Jérémy Berthelet, Rongxing Liu, Saravanan Ganesan, Romain Duval, Fabien Guidez, Linh-Chi Bui, Wenchao Zhang, Qing Nian, Fernando Rodrigues Lima, Christine Chomienne, Thibaut Léger, Florent Busi, Ximing Xu

Publikováno v: Molecular Pharmacology
Molecular Pharmacology, 2019, 96 (2), pp.297-306. ⟨10.1124/mol.119.116319⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2019, 96 (2), pp.297-306. ⟨10.1124/mol.119.116319⟩

International audience; Etoposide is a widely prescribed anticancer drug that is, however, associated with an increased risk of secondary leukemia. Although the molecular basis underlying the development of these leukemias remains poorly understood,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba40d16e2739da887b94868860fb49b
https://pubmed.ncbi.nlm.nih.gov/31221825

Bacterial Arylamine N-Acetyltransferases: From Structures to Applications

Autor: Jean-Marie Dupret, Ximing Xu, Florent Busi, Xavier Kubiak, Fernando Rodrigues-Lima

Publikováno v: Arylamine N-acetyltransferases in Health and Disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2931fd04c3fbb55b46be165c382013f0
https://doi.org/10.1142/9789813232013_0011

Riboregulation of the bacterial actin-homolog MreB by DsrA small noncoding RNA

Autor: Stephane Caulet, Claire Martret, Grzegorz M. Cech, Grzegorz Węgrzyn, Emilie Fortas, Anna Kloska, Marion Barbet, Sergio Marco, Aziz Taghbalout, Sylvain Trépout, Véronique Arluison, Florent Busi, Bastien Cayrol

Publikováno v: Integrative Biology. 7:128-141

The bacterial actin-homolog MreB is a key player in bacterial cell-wall biosynthesis and is required for the maintenance of the rod-like morphology of Escherichia coli. However, how MreB cellular levels are adjusted to growth conditions is poorly und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bcfc9527e723ace485bf1fbf96eaf4e
https://doi.org/10.1039/c4ib00102h