Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells

Autor: Rémi Mascarau, Marie Woottum, Léa Fromont, Rémi Gence, Vincent Cantaloube-Ferrieu, Zoï Vahlas, Kevin Lévêque, Florent Bertrand, Thomas Beunon, Arnaud Métais, Hicham El Costa, Nabila Jabrane-Ferrat, Yohan Gallois, Nicolas Guibert, Jean-Luc Davignon, Gilles Favre, Isabelle Maridonneau-Parini, Renaud Poincloux, Bernard Lagane, Serge Bénichou, Brigitte Raynaud-Messina, Christel Vérollet

Publikováno v: Journal of Cell Biology. 222

Macrophages are essential for HIV-1 pathogenesis and represent major viral reservoirs. Therefore, it is critical to understand macrophage infection, especially in tissue macrophages, which are widely infected in vivo, but poorly permissive to cell-fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84a49f5a2f95ad5adfbbf97a84712fff
https://doi.org/10.1083/jcb.202205103

HIV-1-Infected Human Macrophages, by Secreting RANK-L, Contribute to Enhanced Osteoclast Recruitment

Autor: Brigitte Raynaud-Messina, Florent Bertrand, Isabelle Gennero, Christel Vérollet, Isabelle Maridonneau-Parini, Arnaud Labrousse, Renaud Poincloux, Rémi Mascarau

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2020, 21 (9), pp.3154. ⟨10.3390/ijms21093154⟩
International Journal of Molecular Sciences, Vol 21, Iss 3154, p 3154 (2020)
Volume 21
Issue 9
International Journal of Molecular Sciences, MDPI, 2020, 21 (9), pp.3154. ⟨10.3390/ijms21093154⟩
International Journal of Molecular Sciences, MDPI, 2020, 21 (9), ⟨10.3390/ijms21093154⟩

HIV-1 infection is frequently associated with low bone density, which can progress to osteoporosis leading to a high risk of fractures. Only a few mechanisms have been proposed to explain the enhanced osteolysis in the context of HIV-1 infection. As

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632fa5f56186f0c599533c89debe0148
https://doi.org/10.3390/ijms21093154