Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Florencia A. deLuna"'
Publikováno v:
Pharmaceutical Research. :608-614
MK-417 is a potent carbonic anhydrase inhibitor currently under clinical investigation as a topical ocular hypotensive agent. While present in most of the tissues, carbonic anhydrase predominates in red blood cells. Earlier studies from our laborator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82b41180c16bc96699c540a705eafa0b
https://doi.org/10.1023/a:1015804707206
https://doi.org/10.1023/a:1015804707206
Autor:
Paul G. Pearson, Elizabeth M. Migoya, Punam Sandhu, G. Mistry, Julie A. Stone, Stacy C. Dilzer, Xin Xu, Kenneth C. Lasseter, Gregory A. Winchell, Deutsch Paul J, Alisha R. Miller, Florencia A. deLuna, Liwen Xi, Romi Singh
The disposition of caspofungin, a parenteral antifungal drug, was investigated. Following a single, 1-h, intravenous infusion of 70 mg (200 μCi) of [ 3 H]caspofungin to healthy men, plasma, urine, and feces were collected over 27 days in study A ( n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07ae141532e4ac999bf0f908934e149
https://europepmc.org/articles/PMC353127/
https://europepmc.org/articles/PMC353127/
Publikováno v:
Journal of pharmaceutical sciences. 83(12)
Alendronate is an antiosteolytic agent under investigation for the treatment of a number of bone disorders. Since the compound is a zwitterion with five pKa values and is completely ionized in the intestine at the physiological pH, absorption is poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468829125fbb291b53607d3da8b65728
https://pubmed.ncbi.nlm.nih.gov/7891304
https://pubmed.ncbi.nlm.nih.gov/7891304
Publikováno v:
Journal of cardiovascular pharmacology. 2(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c5347f10b989d462a73f88a8481ae9
https://pubmed.ncbi.nlm.nih.gov/6171681
https://pubmed.ncbi.nlm.nih.gov/6171681
Publikováno v:
Journal of pharmaceutical sciences. 64(11)
A GLC procedure was developed for measuring nanogram quantities of timolol in plasma and urine. The unchanged drug was extracted into heptane–4% isoamyl alcohol from alkalinized plasma or urine, together with a homolog of timolol which served as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5b23766d0b39958fa9c9247a8e935c
https://pubmed.ncbi.nlm.nih.gov/1195122
https://pubmed.ncbi.nlm.nih.gov/1195122