Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Florence W. Patten"'
Multimodal 3D Imaging of Cells and Tissue, Bridging the Gap Between Clinical and Research Microscopy
Publikováno v:
Annals of Biomedical Engineering. 40:263-276
Absorption dyes are widely used in traditional cytology and pathology clinical practice, while fluorophores and nanoparticles are more often used in biologic research. Optical projection tomographic microscopy (OPTM) is a platform technology that can
Autor:
Florence W. Patten, Michael G. Meyer, Alan C. Nelson, Mark E. Fauver, Eric J. Seibel, J. Richard Rahn, Thomas Neumann
Publikováno v:
Pattern Recognition. 42:141-146
Optical projection tomographic microscopy is a technique that allows 3D analysis of individual cells. Theoretically, 3D morphometry would more accurately capture cellular features than 2D morphometry. To evaluate this thesis, classifiers based on 3D
Autor:
Florence W. Patten
Publikováno v:
Acta Cytologica. 46:603-606
Publikováno v:
2014 IEEE Healthcare Innovation Conference (HIC).
The clinical utility of DNA ploidy as prognostic indicator is well established for cancer. Quantitative measures of DNA are possible in cell populations with flow cytometry (FCM) and individual cells with image cytometry (ICM). Because ICM can be mor
Autor:
David J. Zahniser, Annekathryn Goodman, Martha L. Hutchinson, Katherine K. Mui, Kurt L. Douglass, Anne A. Hurley, Florence W. Patten, Louise M. Isenstein
Publikováno v:
American Journal of Clinical Pathology. 101:215-219
Recent clinical trials indicated that the ThinPrep method of sample preparation has greater diagnostic sensitivity than the conventional direct Papanicolaou smear. The authors hypothesized that nonhomogeneous cell sampling during transfer from the sa
Autor:
Thomas Neumann, William J. Frable, Muhammad B. Zaman, Alan C. Nelson, Yener S. Erozan, Florence W. Patten, Fred L. Johnson, Michael G. Meyer, Prabodh K. Gupta
Publikováno v:
Cancer. 117(6)
BACKGROUND: The objective of this study was to assess the frequency of premalignant and malignant cells in sputum from patients with lung cancer and to measure the dependence of these cells on cancer stage, histologic type, tumor size, and tumor loca
Autor:
Thomas Neumann, J. Richard Rahn, Florence W. Patten, Mark E. Fauver, Michael G. Meyer, Alan C. Nelson, Eric J. Seibel
Publikováno v:
Frontiers in Optics.
A newly developed optical projection tomography microscope generates three-dimensional images of absorption-stained nuclei with submicron isometric resolution.
Publikováno v:
SPIE Proceedings.
The Micro-Optical Projection Tomographic Microscope (μOPTM) is an instrument that is being developed for three-dimensional (3D) imaging of cells and subcellular components. The target application for the μOPTM is the early detection of lung cancer
Publikováno v:
Journal of the American Society of Cytopathology. 1:S6-S7
Publikováno v:
Journal of Medical Imaging. 1:017501
Aneuploidy is typically assessed by flow cytometry (FCM) and image cytometry (ICM). We used optical projection tomographic microscopy (OPTM) for assessing cellular DNA content using absorption and fluorescence stains. OPTM combines some of the attrib