Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Florence Vrignaud"'
Autor:
Brigitte Dréno, Jean-Michel Nguyen, Ewa Hainaut, Laurent Machet, Marie-Thérèse Leccia, Nathalie Beneton, Jean-Paul Claudel, Philippe Célérier, Marie Le Moigne, Sarah Le Naour, Florence Vrignaud, Alexandra Poinas, Cécile Dert, Aurélie Boisrobert, Laurent Flet, Simon Korner, Amir Khammari
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
Acne in adult females is triggered mainly by hormones. Doxycycline is a reference treatment in acne. Spironolactone targets the androgen receptor of sebaceous glands and is prescribed off-label for female adult acne. This multicentre, controlled, ran
Externí odkaz:
https://doaj.org/article/c35f812809d84afaad9346a99b761aa2
Autor:
Alexandra Poinas, Marie Lemoigne, Sarah Le Naour, Jean-Michel Nguyen, Solène Schirr-Bonnans, Valery-Pierre Riche, Florence Vrignaud, Laurent Machet, Jean-Paul Claudel, Marie-Thérèse Leccia, Ewa Hainaut, Nathalie Beneton, Cécile Dert, Aurélie Boisrobert, Laurent Flet, Anne Chiffoleau, Stéphane Corvec, Amir Khammari, Brigitte Dréno
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Acne vulgaris has increased in women over the past 10 years; it currently affects 20–30% of women. The physiopathology of adult female acne is distinguished from that of teenagers essentially by two factors: hormonal and inflamm
Externí odkaz:
https://doaj.org/article/9afc2f4f1dc141fea96837116917d020
Autor:
Alexandra Poinas, Pierre Perrot, Judith Lorant, Olivier Nerrière, Jean-Michel Nguyen, Soraya Saiagh, Cécile Frenard, Audrey Leduc, Olivier Malard, Florent Espitalier, Franck Duteille, Anne Chiffoleau, Florence Vrignaud, Amir Khammari, Brigitte Dréno
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Wound repair is one of the most complex biological processes of human life. Allogeneic cell-based engineered skin substitutes provide off-the-shelf temporary wound coverage and act as biologically active dressings, releasing growt
Externí odkaz:
https://doaj.org/article/33c45434f8794628a2f8009d84635386
Autor:
Florence Vrignaud, Olivier Nerriere, Norbert Winer, Alexandra Poinas, Judith Lorant, Amir Khammari, Cécile Frenard, Brigitte Dréno
Publikováno v:
European Journal of Dermatology
European Journal of Dermatology, John Libbey Eurotext, 2019, 29 (6), pp.585-595. ⟨10.1684/ejd.2019.3675⟩
European Journal of Dermatology, John Libbey Eurotext, 2019, 29 (6), pp.585-595. ⟨10.1684/ejd.2019.3675⟩
The skin is the first protective barrier of our body. Wound healing is therefore an essential mechanism. However, this phenomenon can be impaired when wounds are too large or chronic, for example, in diabetes. Interestingly, adult skin heals with sca
Autor:
Olivier Malard, Cécile Frenard, Audrey Leduc, Florent Espitalier, Soraya Saiagh, Florence Vrignaud, Jean-Michel Nguyen, Brigitte Dréno, Franck Duteille, Alexandra Poinas, Anne Chiffoleau, Judith Lorant, Olivier Nerriere, Pierre Perrot, Amir Khammari
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-10 (2019)
Trials
Trials, BioMed Central, 2019, 20 (1), pp.612. ⟨10.1186/s13063-019-3718-4⟩
Trials, 2019, 20 (1), pp.612. ⟨10.1186/s13063-019-3718-4⟩
Trials
Trials, BioMed Central, 2019, 20 (1), pp.612. ⟨10.1186/s13063-019-3718-4⟩
Trials, 2019, 20 (1), pp.612. ⟨10.1186/s13063-019-3718-4⟩
BackgroundWound repair is one of the most complex biological processes of human life. Allogeneic cell-based engineered skin substitutes provide off-the-shelf temporary wound coverage and act as biologically active dressings, releasing growth factors,
Autor:
Florence Vrignaud, Fabrice Bonnet, Anne Dompmartin, Alexandra Jobert, David Boutoille, Brigitte Dreno, Amir Khammari, Jean-Michel Nguyen, Julie Cassecuel, Gilles Garcia, Laurent Flet, Alexandra Poinas, Cédric Rat, Lionel Piroth, Marie-Thérèse Leccia, Soizic Boinet, Pierre Gandon, Eve Maubec
Background: The DYNAMIC study is based on three properties of tetracyclines. (1) Tetracyclines are known to chelate zinc from matrix metalloproteinases. It is possible their chelating activity may help inhibit COVID-19 infection by limiting its abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d879a5b64887fa1bb1cadb9ff629d36
https://doi.org/10.21203/rs.3.rs-29729/v2
https://doi.org/10.21203/rs.3.rs-29729/v2
Autor:
Soizic Boinet, Lionel Piroth, Gilles Garcia, Alexandra Poinas, Anne Dompmartin, Cédric Rat, Alexandra Jobert, Jean-Michel Nguyen, Florence Vrignaud, Marie-Thérèse Leccia, Amir Khammari, Laurent Flet, David Boutoille, Julie Cassecuel, Eve Maubec, Fabrice Bonnet, Brigitte Dreno, Pierre Gandon
Background: The DYNAMIC study is based on three properties of tetracyclines. (1) Tetracyclines are known to chelate zinc from metalloproteases (MMPs). It is possible that their chelating activity may help to inhibit COVID-19 infection by limiting its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fe9572aff2fb590b8bced0d081bc048
https://doi.org/10.21203/rs.3.rs-29729/v1
https://doi.org/10.21203/rs.3.rs-29729/v1
Autor:
Alexandra Poinas, Marie Lemoigne, Sarah Le Naour, Jean-Michel Nguyen, Solène Schirr-Bonnans, Valery-Pierre Riche, Florence Vrignaud, Laurent Machet, Jean-Paul Claudel, Marie-Thérèse Leccia, Ewa Hainaut, Nathalie Beneton, Cécile Dert, Aurélie Boisrobert, Laurent Flet, Anne Chiffoleau, Stéphane Corvec, Amir Khammari, Brigitte Dréno
Background: Acne vulgaris of adult females has increased over the past 10 years; it affects currently 20 to 30% of adult females. The physiopathology of adult female acne is distinguished from that of teenagers essentially by two factors: hormonal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd22b3f4f9d53f8fc80fde8866de798
https://doi.org/10.21203/rs.3.rs-20547/v2
https://doi.org/10.21203/rs.3.rs-20547/v2
Autor:
Alexandra Poinas, Marie Lemoigne, Sarah Le Naour, Jean-Michel Nguyen, Solène Schirr-Bonnans, Valery-Pierre Riche, Florence Vrignaud, Laurent Machet, Jean-Paul Claudel, Marie-Thérèse Leccia, Ewa Hainaut, Nathalie Beneton, Cécile Dert, Aurélie Boisrobert, Laurent Flet, Anne Chiffoleau, Stéphane Corvec, Amir Khammari, Brigitte Dréno
Background Acne vulgaris of adult woman has increased over the past 10 years; it affects currently 20 to 30% of adult women. The physiopathology of adult woman acne is distinguished from the teenager one essentially by 2 factors: hormonal one with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df848ea066d3ed70f334457dcb093fd8
https://doi.org/10.21203/rs.3.rs-20547/v1
https://doi.org/10.21203/rs.3.rs-20547/v1
Autor:
Philippe Lecerf, Alexandra Poinas, Sylvie Sacher Huvelin, Isabelle Mahe Galisson, Christine Fuzeau, Florence Vrignaud, Coralie Gibouleau, Brigitte Dréno, Charlène Padioleau, Sylvie Deblois, Jean-Noël Trochu
Publikováno v:
Thérapie
Thérapie, EDP Sciences, 2019, 74, pp.665-674. ⟨10.1016/j.therap.2019.06.003⟩
Thérapie, EDP Sciences, 2019, 74, pp.665-674. ⟨10.1016/j.therap.2019.06.003⟩
Resume L’investigation clinique au CHU de Nantes est realisee au sein du departement investigation, compose d’une coordination et de 24 equipes de recherche clinique reunies sur quatre sites hospitaliers differents. Ces Unites d’Investigation C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465a6a4b1ba79495c8ff620d5a03678d
https://hal.archives-ouvertes.fr/hal-03488538/document
https://hal.archives-ouvertes.fr/hal-03488538/document