The neuronal tyrosine kinase receptor ligand ALKAL2 mediates persistent pain

Autor: Manon Defaye, Mircea C. Iftinca, Vinicius M. Gadotti, Lilian Basso, Nasser S. Abdullah, Mélissa Cuménal, Francina Agosti, Ahmed Hassan, Robyn Flynn, Jérémy Martin, Vanessa Soubeyre, Gaetan Poulen, Nicolas Lonjon, Florence Vachiery-Lahaye, Luc Bauchet, Pierre Francois Mery, Emmanuel Bourinet, Gerald W. Zamponi, Christophe Altier

Publikováno v: The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)

The anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase known for its oncogenic potential that is involved in the development of the peripheral and central nervous system. ALK receptor ligands ALKAL1 and ALKAL2 were recently found to promo

Externí odkaz: https://doaj.org/article/a6e3c5ad613d48638247c916de48a347

Microbial contamination and tissue procurement location: A conventional operating room is not mandatory. An observational study.

Autor: Benjamin Louart, Claire Charles, Tri-Long Nguyen, Nicolas Builles, Claire Roger, Jean-Yves Lefrant, Florence Vachiery-Lahaye, John De Vos, Guilhem Couderc, Laurent Muller

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210140 (2019)

BackgroundStandard operating rooms (SOR) are assumed to be the best place to prevent microbial contamination when performing tissue procurement. However, mobilizing an operating room is time and cost consuming if no organ retrieval is performed. In s

Externí odkaz: https://doaj.org/article/d42c7241802046409fc01c99b1300877

Isolation and Culture of Precursor Cells from the Adult Human Spinal

Autor: Florence Vachiery-Lahaye, Florence E. Perrin, Emmanuel Bourinet, L. Bauchet, Jean-Philippe Hugnot, Nicolas Lonjon, Gaëtan Poulen

Publikováno v: Neural Progenitor Cells
Neural Progenitor Cells, 2389, Springer US, pp.103-110, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1783-0_10⟩
Methods in Molecular Biology ISBN: 9781071617823
Methods in Molecular Biology

International audience; We demonstrated the presence of neural stem cells and/or progenitor cells in the adult human spinal cord. This chapter provides materials and methods to harvest high-quality samples of thoracolumbar, lumbar, and sacral adult h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac996fec65bf82f618634b22b50d8c6
https://hal.archives-ouvertes.fr/hal-03475956

Persistence of FoxJ1+ Pax6+ Sox2+ ependymal cells throughout life in the human spinal cord

Autor: Chantal Ripoll, Gaetan Poulen, Robert Chevreau, Nicolas Lonjon, Florence Vachiery-Lahaye, Luc Bauchet, Jean-Philippe Hugnot

Spinal cord ependymal cells have stem cell properties in mice. They surround the central canal and keep expressing spinal cord developmental transcription factors. Similar cells exist in young humans however their persistence with aging is debated.We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cc78d4c3458285d7bb3429d107ee692
https://doi.org/10.1101/2022.08.01.502176

Isolation and Culture of Precursor Cells from the Adult Human Spinal Cord

Autor: Luc, Bauchet, Gaetan, Poulen, Nicolas, Lonjon, Florence, Vachiery-Lahaye, Emmanuel, Bourinet, Florence Evelyne, Perrin, Jean-Philippe, Hugnot

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2389

We demonstrated the presence of neural stem cells and/or progenitor cells in the adult human spinal cord. This chapter provides materials and methods to harvest high-quality samples of thoracolumbar, lumbar, and sacral adult human spinal cord and hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a95a3e48e04c1942424c77d929da4a49
https://pubmed.ncbi.nlm.nih.gov/34558006