Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Florence T Bourgeois"'
Publikováno v:
PLoS Medicine, Vol 16, Iss 11, p e1002922 (2019)
BACKGROUND:Prescription opioid misuse has become a leading cause of unintentional injury and death among adolescents and young adults in the United States. However, there is limited information on how adolescents and young adults obtain prescription
Externí odkaz:
https://doaj.org/article/f6da82c52586400590640306b89232d9
Publikováno v:
PLoS Medicine, Vol 16, Iss 11, p e1002966 (2019)
BackgroundRare diseases affect as many as 60 million people in the United States and Europe. However, most rare diseases lack effective therapies and are in critical need of clinical research. Our objective was to determine the frequency of noncomple
Externí odkaz:
https://doaj.org/article/f326704886594cd2898679a86445d1a9
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226433 (2019)
OBJECTIVE:To describe temporal trends and factors associated with opioid administration among children discharged from the emergency department (ED) after a trauma visit. METHODS:This was a cross-sectional study of ED visits for children
Externí odkaz:
https://doaj.org/article/92309b9adf18450b9d65dc102fafd8e0
Autor:
Chris A Rees, Peter J Hotez, Michael C Monuteaux, Michelle Niescierenko, Florence T Bourgeois
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0007111 (2019)
BACKGROUND:Despite the known burden of neglected tropical diseases (NTDs) on child health, there is limited information on current efforts to increase pediatric therapeutic options. Our objective was to quantify and characterize research activity and
Externí odkaz:
https://doaj.org/article/ee4a80028649411f9a3ce04d9e58b6d1
Publikováno v:
PLoS Medicine, Vol 15, Iss 3, p e1002520 (2018)
BACKGROUND:Few medicines have been approved for children, leading to rates of off-label prescribing reported to be as high as 90%. In 2007, the European Union adopted the Paediatric Regulation, which mandates that pharmaceutical companies conduct pae
Externí odkaz:
https://doaj.org/article/f92584c95aae453babed09cfa54f4787
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155948 (2016)
BACKGROUND:Elderly patients represent the greatest consumers of healthcare per capita but have historically been underrepresented in clinical trials. It is unknown how many trials are designed to focus exclusively on elderly patients. OBJECTIVE:To de
Externí odkaz:
https://doaj.org/article/c56bc58430d8433583498b36600155ee
Autor:
Alexandra T. Geanacopoulos, MD, Ann Chen Wu, MD, MPH, Florence T. Bourgeois, MD, MPH, Alon Peltz, MD, MBA, MHS, Ryan Walsh, BS, Amy Han, MPH, Mei-Sing Ong, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 4, Pp 100315- (2024)
Background: The existing data on enrollment trends of historically underserved racial and ethnic children in clinical trials are limited. Objective: We sought to evaluate documentation and representation of race and ethnicity in pediatric asthma clin
Externí odkaz:
https://doaj.org/article/3d94955ae8bf412eb9996b950be00446
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102249 (2014)
Attention-deficit hyperactivity disorder (ADHD) is a chronic condition and pharmacotherapy is the mainstay of treatment, with a variety of ADHD medications available to patients. However, it is unclear to what extent the long-term safety and efficacy
Externí odkaz:
https://doaj.org/article/070f26800efc408b99550bec90eed998
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84951 (2013)
Pediatric populations continue to be understudied in clinical drug trials despite the increasing use of pharmacotherapy in children, particularly with psychotropic drugs. Most pertinent to the clinical selection of drug interventions are trials direc
Externí odkaz:
https://doaj.org/article/f31a19f7f55f437aaec6a263845336b7
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28820 (2012)
The $1.1 billion investment in comparative effectiveness research will reshape the evidence-base supporting decisions about treatment effectiveness, safety, and cost. Defining the current prevalence and characteristics of comparative effectiveness (C
Externí odkaz:
https://doaj.org/article/d56a83b3abba43389f091c8755e3a3d9