Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Florence Slits"'
Autor:
Beat Moeckli, Vaihere Delaune, Benoît Gilbert, Andrea Peloso, Graziano Oldani, Sofia El Hajji, Florence Slits, Joana Rodrigues Ribeiro, Ruben Mercier, Adrien Gleyzolle, Laura Rubbia-Brandt, Quentin Gex, Stephanie Lacotte, Christian Toso
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101056- (2024)
Background & Aims: Emerging evidence suggests that maternal obesity negatively impacts the health of offspring. Additionally, obesity is a risk factor for hepatocellular carcinoma (HCC). Our study aims to investigate the impact of maternal obesity on
Externí odkaz:
https://doaj.org/article/be3cc441d2a74a13831714a5af507393
Autor:
Stéphanie Lacotte, Florence Slits, Beat Moeckli, Andrea Peloso, Stéphane Koenig, Matthieu Tihy, Sofia El Hajji, Quentin Gex, Laura Rubbia-Brandt, Christian Toso
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTNonalcoholic steatohepatitis (NASH) can lead to hepatocellular carcinoma (HCC). Although immunotherapy is used as first-line treatment for advanced HCC, the impact of NASH on anticancer immunity is only partially characterized. We assessed th
Externí odkaz:
https://doaj.org/article/eda85c03da7042f988ca15954d775c81
Autor:
Andrea Peloso, Stéphanie Lacotte, Quentin Gex, Florence Slits, Beat Moeckli, Graziano Oldani, Matthieu Tihy, Aurélie Hautefort, Brenda Kwak, Laura Rubbia-Brandt, Christian Toso
Publikováno v:
PLoS ONE, Vol 18, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/afcfd49c6704415a8412e784975d0771
Autor:
Beat Moeckli, Thuy-Vy Pham, Florence Slits, Samuel Latrille, Andrea Peloso, Vaihere Delaune, Graziano Oldani, Stéphanie Lacotte, Christian Toso
Publikováno v:
Heliyon, Vol 8, Iss 11, Pp e11490- (2022)
Objective: Obesity and associated liver disease are a growing public health concern. Pharmacological agents to treat non-alcoholic fatty liver disease are limited. FGF21, a hormone secreted by the liver and potent metabolic modulator, is a promising
Externí odkaz:
https://doaj.org/article/2ad3d0355d874458b8da622a61c948d8
Autor:
Beat Moeckli, Vaihere Delaune, Julien Prados, Matthieu Tihy, Andrea Peloso, Graziano Oldani, Thomas Delmi, Florence Slits, Quentin Gex, Laura Rubbia-Brandt, Nicolas Goossens, Stéphanie Lacotte, Christian Toso
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 294 (2022)
The global obesity epidemic particularly affects women of reproductive age. Offspring of obese mothers suffer from an increased risk of liver disease but the molecular mechanisms involved remain unknown. We performed an integrative genomic analysis o
Externí odkaz:
https://doaj.org/article/76df5cf219df44ef827aeb6d794660f4
Autor:
Lorenzo A. Orci, Graziano Oldani, Stephanie Lacotte, Florence Slits, Iris Friedli, Wolfgang Wirth, Christian Toso, Jean-Paul Vallée, Lindsey A. Crowe
Publikováno v:
Journal of Investigative Surgery, Vol 31, Iss 1, Pp 44-53 (2018)
Purpose: In vivo liver cancer research commonly uses rodent models. One of the limitations of such models is the lack of accurate and reproducible endpoints for a dynamic assessment of growing tumor nodules. The aim of this study was to validate a no
Externí odkaz:
https://doaj.org/article/bc7b3bcb00b34d77a63c267d632153ce
Autor:
Graziano Oldani, Andrea Peloso, Florence Slits, Quentin Gex, Vaihere Delaune, Lorenzo A Orci, Yohan van de Looij, Didier J Colin, Stéphane Germain, Claudio de Vito, Laura Rubbia-Brandt, Stéphanie Lacotte, Christian Toso
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224890 (2019)
Hypothermic and normothermic ex vivo liver perfusions promote organ recovery after donation after circulatory death (DCD). We tested whether these perfusions can reduce the risk of hepatocellular carcinoma (HCC) recurrence in a 1h-DCD syngeneic trans
Externí odkaz:
https://doaj.org/article/669c7066b840442791ba1174a6afe2c7
Autor:
Vaihere Delaune, Christian Toso, Pierre-Yves Benhamou, Anne Wojtusciszyn, Laurence Kessler, Florence Slits, Sandrine Demuylder-Mischler, Nadine Pernin, Sandrine Lablanche, Lorenzo A. Orci, Graziano Oldani, Philippe Morel, Thierry Berney, Stéphanie Lacotte
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Islet transplantation is an effective treatment for selected patients with type 1 diabetes. However, an accurate test still lacks for the early detection of graft rejection. Blood samples were prospectively collected in four university centers (Genev
Externí odkaz:
https://doaj.org/article/317576107deb4bc09477e42c09b24904
Autor:
Stéphanie Lacotte, Graziano Oldani, Florence Slits, Lorenzo A Orci, Laura Rubbia-Brandt, Philippe Morel, Gilles Mentha, Christian Toso
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91515 (2014)
Liver transplantation for hepatocellular carcinoma (HCC) results in a specific condition where the immune response is potentially directed against both allogeneic and cancer antigens. We have investigated the level of anti-cancer immunity during allo
Externí odkaz:
https://doaj.org/article/e3bee9f98a75406aa5bf47b5ad899392
Autor:
Florence Slits, Andrea Peloso, Vanessa Lavallard, Stéphanie Lacotte, Quentin Gex, Lorenzo A. Orci, Arianna Kahler-Quesada, Vaihere Delaune, Gürkan Kaya, Christian Toso
Publikováno v:
Transplant International (2020)
Intraportal islet transplantation is plagued by an acute destruction of transplanted islets. Amongst the first responders, NK cells and macrophages harbour an activating receptor, NKG2D, recognizing ligands expressed by stressed cells. We aimed to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22663da3829e83370abcdaa4dbdf7f6
https://doi.org/10.1111/tri.13589
https://doi.org/10.1111/tri.13589