Výsledky vyhledávání - "Florence Schlosser"

Abstract 5572: IMC-F106C, a novel and potent immunotherapy approach to treat PRAME expressing solid and hematologic tumors

Autor: Florence Schlosser, Laure Humbert, Gabrielle S. Le Provost, Amanda M. Williams, Jane Harper, Jacob Robinson, Greg Dobrynin, Alessio Vantellini, Sylvie Moureau, Athiva Shankar, David Berman

Publikováno v: Cancer Research. 80:5572-5572

Background: Bispecific immunotherapies have been validated for the treatment of hematologic tumors but none have yet been approved for solid tumor indications, including high prevalent tumors such as non-small-cell lung carcinoma (NSCLC). Immunocore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2f1792b4a23f61a88c625dea07a1070
https://doi.org/10.1158/1538-7445.am2020-5572

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Optimizing assembly and production of native bispecific antibodies by codon de-optimization

Autor: Marie Corbier, Nicolas Fischer, Yves Poitevin, Giovanni Magistrelli, Soheila Josserand, Florence Schlosser, Guillemette Pontini, Pauline Malinge

When production of bispecific antibodies requires the co-expression and assembly of three or four polypeptide chains, low expression of one chain can significantly limit assembly and yield. κλ bodies, fully human bispecific antibodies with native I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1496a53afa3283d22c9627977e30aa26
https://europepmc.org/articles/PMC5297534/

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