Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Florence Sallas"'
Autor:
Kevin Sheerin, Arjun Raghuraman, Umesh R. Desai, Nehru Viji Sankarayanarayanan, Florence Sallas, Philip D. Mosier, Nicholas D. Watermeyer, Stefan Oscarson, Rio S. Boothello, Tamara R. Strebel
Publikováno v:
Angewandte Chemie (International Ed. in English)
Glycosaminoglycan (GAG) sequences that selectively target heparin cofactor II (HCII), a key serpin present in human plasma, remain unknown. Using a computational strategy on a library of 46 656 heparan sulfate hexasaccharides we identified a rare seq
Autor:
Matt Gooding, Raphael Darcy, Caitriona M. O'Driscoll, James C. Evans, Meenakshi Malhotra, Kathleen A. Fitzgerald, Florence Sallas
Publikováno v:
International Journal of Pharmaceutics. 499:131-145
Prostate cancer is a leading cause of cancer-related death in men and RNA interference (RNAi) has emerged as a potential therapeutic option. However, the absence of a safe and specific delivery vector remains a major obstacle to the clinical applicat
Autor:
Florence Sallas, Raphael Darcy
Publikováno v:
European Journal of Organic Chemistry. 2008:957-969
Amphiphilic cyclodextrins represent a new generation of these oligosaccharides, which are well known previously as host molecules in water. Cyclodextrins are now being modified with polar groups, lipophilic groups and conjugates which elaborate furth
Autor:
Shin-Ichiro Nishimura, Florence Sallas
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2091-2103
A variety of glycoconjugates bearing either N-acetyllactosamine or sialyl Lewisx units have been synthesised in a chemo-enzymatic way. This includes the synthesis of glycopolymer copolymerised with acrylamide and whose glucosamine unit was substitute
Autor:
Florence Sallas, Laszlo Jicsinszky, Joseph Kovács, Virginie Petot, Alain Marsura, István Pintér
Publikováno v:
Helvetica Chimica Acta. 81:632-645
The synthesis of new ‘bridged’ β-cyclodextrin (β-CD) ‘dimers’ 7–12 was successfully achieved by two one-pot reactions from β-CD (3) and 6A-azido-6A-deoxy-β-CD (4). The ‘phosphine imine’ reaction was shown to be a superior approach c
Publikováno v:
Tetrahedron Letters. 37:4011-4014
The synthesis of new bridged [~-eyciodextrin dimers (CDs) has been successfully achieved by a one pot transformation of 6-monoazido-6-monodeoxy-13-CDs 2 and $ via the phosphinimines. Pseudo-first-order rate constants hydrolysis of bis-(-p-nitrophenyl
Publikováno v:
Tetrahedron Letters. 35:6079-6082
The synthesis of mono and disubstituted β-CD thio derivatives has been successfully achieved by a thio-Mitsunobu reaction with a thio-saccharide and aromatic thiols directly on unprotected β-CD.
Autor:
Alain Marsura, Joseph Kovács, István Pintér, Virginie Petot, Florence Sallas, Laszlo Jicsinszky
Publikováno v:
ChemInform. 29
The synthesis of new ‘bridged’ β-cyclodextrin (β-CD) ‘dimers’ 7–12 was successfully achieved by two one-pot reactions from β-CD (3) and 6A-azido-6A-deoxy-β-CD (4). The ‘phosphine imine’ reaction was shown to be a superior approach c
Autor:
Florence Sallas, Raphael Darcy
Publikováno v:
ChemInform. 39
Amphiphilic cyclodextrins represent a new generation of these oligosaccharides, which are well known previously as host molecules in water. Cyclodextrins are now being modified with polar groups, lipophilic groups and conjugates which elaborate furth
Publikováno v:
Chemical communications (Cambridge, England). (5)
New amphiphilic cyclodextrins fully substituted with sugar residues on the primary face have been synthesised and enzymatically modified.