Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Florence S.G. Cheung"'
Autor:
Florence S.G. Cheung, Thomas Grewal, Ling Zhu, Fanfan Zhou, Xiaoxi Lu, Jian Zheng, Ting Chan, Michael Murray
Publikováno v:
Molecular Pharmaceutics. 13:144-154
Human organic anion transporting polypeptides (OATPs) mediate the influx of many important drugs into cells. Casein kinase 2 (CK2) is a critical protein kinase that phosphorylates300 protein substrates and is dysregulated in a number of disease state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3dcbaec370ff17cd542d6c6e2402c8
https://doi.org/10.1021/acs.molpharmaceut.5b00576
https://doi.org/10.1021/acs.molpharmaceut.5b00576
Publikováno v:
Human Mutation. 36:196-199
It has been established that up to 8.3% of the biallelic coding SNPs present in dbSNP are actually artefactual polymorphism-like errors, previously termed single nucleotide differences, or SNDs. In this study, a previous analysis of SNPs in dbSNP was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09387e9adf350700cbb933a665c8f3b1
https://doi.org/10.1002/humu.22735
https://doi.org/10.1002/humu.22735
Publikováno v:
Endocrine-related cancer. 24(12)
Recent success in immunomodulating strategies in lung cancer and melanoma has prompted much enthusiasm in their potential to treat other advanced solid malignancies. However, their applications have shown variable success and are even ineffective aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292a46862c19295383a24c8fd2e23d50
https://pubmed.ncbi.nlm.nih.gov/28754821
https://pubmed.ncbi.nlm.nih.gov/28754821
Publikováno v:
Pharmaceutical Biology. 52:1510-1517
Context: Solute carrier transporters (SLCs) are membrane proteins responsible for cellular influx of various substances including many pharmaceutical agents; therefore, they largely impact on drug disposition and elimination in body. Punica granatum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322f9abf9532cc7e4536bfd5b0c11220
https://doi.org/10.3109/13880209.2014.900809
https://doi.org/10.3109/13880209.2014.900809
Interaction of the Bioactive Flavonol, Icariin, with the Essential Human Solute Carrier Transporters
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 28:91-97
Solute carrier transporters (SLCs), in particular the organic anion transporting polypeptides (OATPs) and organic anion/cation transporters (OATs/OCTs), are responsible for the cellular entry of many clinically important drugs in body. They largely i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c8ed9406650bc2a902d2c99f14fbc0
https://doi.org/10.1002/jbt.21540
https://doi.org/10.1002/jbt.21540
Autor:
Zhen Li, Ting Chan, Ling Zhu, Hongxiang Zhuge, Florence S.G. Cheung, Fei Xu, Jian Zheng, Fanfan Zhou
Publikováno v:
Journal of Pharmaceutical Sciences. 102:4205-4211
Solute carrier transporters (SLCs), in particular the organic anion transporters (OATs), OAT polypeptides (OATPs), and organic cation transporters (OCTs/OCTNs), are the important membrane proteins responsible for the cellular influx of various drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866349af9a216400fd53522d62cd8cd0
https://doi.org/10.1002/jps.23727
https://doi.org/10.1002/jps.23727
Autor:
Florence S.G. Cheung, Nikki Y. Tan, Shubhita Tripathi, Manuel Adrian Suter, Muznah Khatoo, Zhi Huan Chew, Stephan Gasser, Joanne Ngeow, Wendy Y.L. Zhang
Publikováno v:
Mechanisms of ageing and development. 165
The presence of damaged and microbial DNA can pose a threat to the survival of organisms. Cells express various sensors that recognize specific aspects of such potentially dangerous DNA. Recognition of damaged or microbial DNA by sensors induces cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6c1b911851bb909e5129487579052b
https://pubmed.ncbi.nlm.nih.gov/27614000
https://pubmed.ncbi.nlm.nih.gov/27614000
Publikováno v:
Expert Review of Anticancer Therapy. 12:811-837
Vitamin D has long been known for its physiological role in mineral homeostasis through its actions on the intestines, kidneys, parathyroid glands and bone. However, recent observations of antiproliferative, prodifferentiating and antiangiogenic effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76aa7b0b6a2c780bbec83be34db042e
https://doi.org/10.1586/era.12.53
https://doi.org/10.1586/era.12.53
Autor:
Jonathan W. Arthur, Scott M. Lippman, Florence S.G. Cheung, Lucia Musumeci, Ashraful Hoque, Juergen K. V. Reichardt
Publikováno v:
Human Mutation. 31:67-73
This file contains a complete list of single nucleotide differences (SNDs) identified in the research described in the paper: "Single Nucleotide Differences (SNDs) in the dbSNP Database May Lead to Errors in Genotyping and Haplotyping Studies" Lucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d0491b16f3584042b2d6da86c53964
https://doi.org/10.1002/humu.21137
https://doi.org/10.1002/humu.21137
Autor:
Manuel Adrian Suter, Puay Hoon Tan, Muznah Khatoo, Nikki Y. Tan, Florence S.G. Cheung, Samantha S.W. Ho, Wendy Y.L. Zhang, Shubhita Tripathi, Stephan Gasser, Joanne Ngeow, Weng Khong Lim
Publikováno v:
Immunity. 44(5)
Self-DNA is present in the cytosol of many cancer cells and can promote effective immune rejection of tumor cells, but the mechanisms leading to the presence of cytosolic DNA are unknown. Here, we report that the cleavage of genomic DNA by DNA struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904fb55ff86d7a2ec170bc9f295686de
https://pubmed.ncbi.nlm.nih.gov/27178469
https://pubmed.ncbi.nlm.nih.gov/27178469