Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Florence P. H. Gay"'
Autor:
Abdellah Allali-Hassani, Magdalena M. Szewczyk, Danton Ivanochko, Shawna L. Organ, Jabez Bok, Jessica Sook Yuin Ho, Florence P. H. Gay, Fengling Li, Levi Blazer, Mohammad S. Eram, Levon Halabelian, David Dilworth, Genna M. Luciani, Evelyne Lima-Fernandes, Qin Wu, Peter Loppnau, Nathan Palmer, S. Zakiah A. Talib, Peter J. Brown, Matthieu Schapira, Philipp Kaldis, Ronan C. O’Hagan, Ernesto Guccione, Dalia Barsyte-Lovejoy, Cheryl H. Arrowsmith, John M. Sanders, Solomon D. Kattar, D. Jonathan Bennett, Benjamin Nicholson, Masoud Vedadi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
PRDM9 is a PR domain containing histone methyl transferase which expression is normally restricted to the germline that has also been linked to a number of somatic cancers. Here the authors describe the identification of a small molecule that selecti
Externí odkaz:
https://doaj.org/article/38d967925aeb49498c5e1209a2983c26
Autor:
Cheryl M. Koh, Marco Bezzi, Diana H. P. Low, Wei Xia Ang, Shun Xie Teo, Florence P. H. Gay, Muthafar Al-Haddawi, Soo Yong Tan, Motomi Osato, Arianna Sabò, Bruno Amati, Keng Boon Wee, Ernesto Guccione
Publikováno v:
Nature. 523(7558)
Deregulated expression of the MYC transcription factor occurs in most human cancers and correlates with high proliferation, reprogrammed cellular metabolism and poor prognosis. Overexpressed MYC binds to virtually all active promoters within a cell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18899193988d8ff0eb0a02514e1ca97
https://pubmed.ncbi.nlm.nih.gov/26084393
https://pubmed.ncbi.nlm.nih.gov/26084393