Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Florence Noble"'
Autor:
Nicolas Marie, Florence Noble
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
The over-prescription of opioid analgesics is a growing problem in the field of addiction, which has reached epidemic-like proportions in North America. Over the past decade, oxycodone has gained attention as the leading opioid responsible for the No
Externí odkaz:
https://doaj.org/article/fd7c0b1442fe43d59d3769aa4ea782f0
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Substance use disorders (SUD) may emerge from an individual’s attempt to limit negative affective states and symptoms linked to stress. Indeed, SUD is highly comorbid with chronic stress, traumatic stress, or post-traumatic stress disorder (PTSD),
Externí odkaz:
https://doaj.org/article/a10a97e997624e058935980aed51401e
Autor:
Florence Noble, Nicolas Marie
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
Opioid are the most powerful analgesics ever but their use is still limited by deleterious side effects such as tolerance, dependence, and respiratory depression that could eventually lead to a fatal overdose. The opioid crisis, mainly occurring in n
Externí odkaz:
https://doaj.org/article/2dcf450cc48a48c8a44019a1b1059453
Autor:
Eleni Paizanis, Michela Crotti, Anthony Petit, Mathilde Règue, Virginie Beray-Berthat, Florence Noble, Laurence Lanfumey, Raymond Mongeau
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Comorbidity between drug abuse and post-traumatic stress disorder (PTSD), a stress-related dysregulation of fear responses, is very high. While some drugs are known to increase fear and anxiety, there are only few data regarding interactions between
Externí odkaz:
https://doaj.org/article/60cf3d5f41774188b07bc8c95c42063d
Autor:
Florence Noble, Nicolas Marie
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2019)
With the opioid crisis in North America, opioid addiction has come in the spotlight and reveals the weakness of the current treatments. Two main opioid substitution therapies (OST) exist: buprenorphine and methadone. These two molecules are mu opioid
Externí odkaz:
https://doaj.org/article/a07bd52991194c3491e632defc583e2d
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30241 (2012)
It is well established that cocaine induces an increase of dendritic spines density in some brain regions. However, few studies have addressed the role of this neuroplastic changes in cocaine rewarding effects and have often led to contradictory resu
Externí odkaz:
https://doaj.org/article/b15030b76c9d4daf95069650658e85f8
Publikováno v:
ACS Medicinal Chemistry Letters. 12:1739-1744
Kappa opioid receptor (KOR) PET imaging remains attractive to understand the role of KOR in health and diseases and to help the development of drugs especially for psychiatric disorders such as depression, anxiety, and addiction. The potent and selec
Autor:
Séverine Martin-Lannerée, Sophie Mouillet-Richard, Margaux Ballé, Nicolas Marie, Corinne Canestrelli, Serge H. Ahmed, Jenny M. Gunnersen, Angéline Duché, Loïc Clemenceau, Florence Noble, Sébastien Jacques, Magalie Lenoir, Isabelle Nondier, Isabella Bondi
SUMMARYEscalation of drug use is a hallmark stage in the transition to addiction and uncovering its underlying brain molecular mechanisms constitutes a considerable challenge. Here, we report in rats with extended access to heroin for self-administra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea805dd8388fd87888a7492c684db09
https://hal.archives-ouvertes.fr/hal-03365414
https://hal.archives-ouvertes.fr/hal-03365414
Autor:
Rim Hassouna, Raphaël G. P. Denis, Florence Noble, Serge Luquet, Daniela Cota, Gwenaëlle Le Pen, Hélène Doat, Yacine Chebani, Jacques Pantel, Thierry Leste-Lasserre, Philippe Zizzari, Candice Marion
Publikováno v:
Journal of Endocrinology
Journal of Endocrinology, BioScientifica, 2021, pp.JOE-20-0576.R2. ⟨10.1530/JOE-20-0576⟩
Journal of Endocrinology, 2021, pp.JOE-20-0576.R2. ⟨10.1530/JOE-20-0576⟩
Journal of Endocrinology, BioScientifica, 2021, pp.JOE-20-0576.R2. ⟨10.1530/JOE-20-0576⟩
Journal of Endocrinology, 2021, pp.JOE-20-0576.R2. ⟨10.1530/JOE-20-0576⟩
The growth hormone secretagogue receptor (GHSR) mediates key properties of the gut hormone ghrelin on metabolism and behavior. Nevertheless, most recent observations also support that the GHSR is a constitutively active G protein-coupled receptor (GP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ea8a77ce1b85a9b0b1f0fdbad48152
https://www.hal.inserm.fr/inserm-03365851/document
https://www.hal.inserm.fr/inserm-03365851/document
Autor:
Florence Noble
Publikováno v:
Biologie Aujourd’hui. 213:141-145
L’addiction est une maladie chronique qui engendre de lourdes conséquences, à la fois en termes de santé publique et au niveau économique. Des caractéristiques claires distinguent bien l’usage récréatif et contrôlé, de l’addiction. Ain