Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Florence Meyer‐Losic"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Translational oncology research strives to explore a new aspect: identifying subgroups that exhibit treatment response even during pre-clinical phases. In this study, we focus on PDX models and their implementation in mouse clinical trials (
Externí odkaz:
https://doaj.org/article/952198248aed405b9f3123ff3ebc2509
Autor:
Fotine Libanje, Raphael Delille, Pamela A Young, Sylvie Rolland, Florence Meyer-Losic, Elodie Lewkowicz, Stephan Klinz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract NTSR1 abnormal expression by cancer cells makes it a strategic target for antitumoral therapies, such as compounds that use NTSR1 binding probes to deliver cytotoxic agents to tumor cells. Success of these therapies relies on NTSR1 protein a
Externí odkaz:
https://doaj.org/article/be382bd032474f35b6aa1e1fa79c16c2
Autor:
Sandrine Barbier, Benjamin Beaufils, Ricardo de Miguel, Melissa Reyre, Yannick Le Meitour, Andreanne Lortie, Marc Hillairet de Boisferon, Sophie Chaumeron, Anne Espirito, Lina Fossati, Pauline Lagarde, Stephan Klinz, Arunthathi Thiagalingam, Stéphane Lezmi, Florence Meyer-Losic
Publikováno v:
Oncology and Therapy, Vol 11, Iss 1, Pp 111-128 (2023)
Abstract Introduction Liposomal irinotecan promotes controlled sustained release of irinotecan (CPT-11), therefore, we hypothesize that the therapeutic index (quantitative measurement of the relative efficacy/safety ratio of a drug) will be higher fo
Externí odkaz:
https://doaj.org/article/be2e3c3c269d460ab70f6f7799bd0e5d
Autor:
Pascale Plas, Lorenzo Limana, Denis Carré, Amath Thiongane, Olivier Raguin, Rosalba Mansi, Florence Meyer-Losic, Stéphane Lezmi
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1085 (2022)
Limited experiments have compared the treatment effects of repetitive cycles of radiolabelled somatostatin (SST) analogues. In vitro and in vivo experiments were conducted in an AR42J cancer cell model, comparing the antagonist [177Lu]Lu-satoreotide
Externí odkaz:
https://doaj.org/article/9b5dea50747d4fda984a66cc498c85c7
Autor:
Florence Meyer-Losic, Simon P Newman, Joanna M Day, Michael J Reed, Philip G Kasprzyk, Atul Purohit, Paul A Foster
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80305 (2013)
Despite paclitxael's clinical success, treating hormone-refractory breast cancer remains challenging. Paclitaxel has a poor pharmacological profile, characterized by a low therapeutic index (TIX) caused by severe dose limiting toxicities, such as neu
Externí odkaz:
https://doaj.org/article/72fc20d8905647e1aed52f755a02a4f3
Autor:
Hélène Savel, Sandrine Barbier, Cécile Proust-Lima, Virginie Rondeau, Rodolphe Thiébaut, Florence Meyer-Losic, Laura Richert
Publikováno v:
Cancer Research Communications. 3:140-147
In translational oncology research, the patient-derived xenograft (PDX) model and its use in mouse clinical trials (MCT) are increasingly described. This involves transplanting a human tumor into a mouse and studying its evolution during follow-up or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4287374a47bb029b73d3b4d601c79d3
https://doi.org/10.1158/2767-9764.crc-22-0238
https://doi.org/10.1158/2767-9764.crc-22-0238
Autor:
Jordane Divoux, Sylvie Rolland, Raphael Delille, Clément Levin, Vincent Martin, Pamela Young, Florence Meyer‐Losic, Stephan Klinz
Publikováno v:
European Journal of Immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1af9755777304b3e0d0d73ac6dab48b
https://doi.org/10.1002/eji.202250186
https://doi.org/10.1002/eji.202250186
Autor:
null Jordane Divoux, null Sylvie Rolland, null Raphael Delille, null Clément Levin, null Vincent Martin, null Pamela Young, null Florence Meyer‐Losic, null Stephan Klinz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c195fa6c1a149ca8d838a1e75a91f9
https://doi.org/10.1002/eji.202250186/v3/response1
https://doi.org/10.1002/eji.202250186/v3/response1
Autor:
Laura Richert, Florence Meyer-Losic, Rodolphe Thiébaut, Virginie Rondeau, Cécile Proust-Lima, Sandrine Barbier, Hélène Savel
Residuals analysis of joint shared random effect model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153f19753a5e0ebc775e921446deaef6
https://doi.org/10.1158/2767-9764.22545890
https://doi.org/10.1158/2767-9764.22545890
Autor:
Laura Richert, Florence Meyer-Losic, Rodolphe Thiébaut, Virginie Rondeau, Cécile Proust-Lima, Sandrine Barbier, Hélène Savel
In translational oncology research, the patient-derived xenograft (PDX) model and its use in mouse clinical trials (MCT) are increasingly described. This involves transplanting a human tumor into a mouse and studying its evolution during follow-up or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e608c957a930fe423637b7af8ea4044
https://doi.org/10.1158/2767-9764.c.6551045.v1
https://doi.org/10.1158/2767-9764.c.6551045.v1