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Autor:
Alexander Volosov, Tamsin Mansley, Patrick Pasau, Frédéric Denonne, Sophie Binet, Jean-Marie Nicolas, Philippe Collart, Alan J. Dipesa, Seema Kumar, Alexander Giannaras, Maggi Burton, Dong Zou, Dorin Preda, Tanmoy Ganguly, Karin J. Stebbins, Florence Maounis, Timothy A. Lewis
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(12)
The synthesis and in vitro binding of several new arginine-containing C3aR ligands are reported. DMPK properties and functional activities of selected compounds have been evaluated. One compound is shown to be active in an in vivo model of airway inf