Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Florence Mahlberg Gaudin"'
Autor:
Marion Bamberger, Nicholas Moore, Philippe Lechat, Michel Azizi, Patrick Blin, Myriam Bouhassira, Dominic Cellier, Jean-Paul Demarez, Xavier Duval, François Gueyffier, Claire Le Jeunne, Christian Libersa, Florence Mahlberg-Gaudin, Patrick Maison, Pierre Marquet, Mathieu Molimard, Aurélie Moser, Mira Pavlovic, Pascal Piedbois, Odile Regnier, Jean-Charles Reynier, Catherine Rey-Quinio, Patrick Rossignol, Alain Spriet, Franck Vignal
Publikováno v:
Therapies. 66:331-334
Based on the observation that over the last 30 years the cost of development has risen regularly as the number of new chemical entities reaching the market has fallen, how can "savings" be made in terms of clinical development, the objective being mo
Autor:
Marion Bamberger, Nicholas Moore, Philippe Lechat, Michel Azizi, Patrick Blin, Myriam Bouhassira, Dominic Cellier, Jean-Paul Demarez, Xavier Duval, François Gueyffier, Claire Le Jeunne, Christian Libersa, Florence Mahlberg-Gaudin, Patrick Maison, Pierre Marquet, Mathieu Molimard, Aurélie Moser, Mira Pavlovic, Pascal Piedbois, Odile Regnier, Jean-Charles Reynier, Catherine Rey-Quinio, Patrick Rossignol, Alain Spriet, Franck Vignal
Publikováno v:
Therapies. 66:327-330
Resume Partant de la constatation que depuis 30 ans, le cout du developpement augmente regulierement a mesure que le nombre de nouvelles entites chimiques atteignant le marche decroit, comment faire des « economies » en termes de developpement clin
Autor:
Driss Berdaï, Jean-Michel Hotton, Philippe Lechat, Alexandre Barna, Laurent Becquemont, Jean-François Bergman, Corine Bernaud, Isabelle Boucot, Isabelle Cheiney, Michel Cucherat, Anne d’Andon, Jérôme d’Enfert, Alain Francillon, Elisabeth Frauger, Danièle Girault, Jean-Marc Harlin, Alain Joseph, Catherine Lassale, Florence Mahlberg-Gaudin, Thierry Moreau-Defarges, Mira Pavlovic, Sophie Ravoire, Lise Rochaix, Eric Vicaut
Publikováno v:
Therapies. 65:329-334
Drug evaluation is based on comparison. Thus, the choice of the comparator for any new treatment becomes a key issue, especially when there are great differences in medical practice and of use conditions of the comparators depending on the geographic
Autor:
Driss Berdaï, Jean-Michel Hotton, Philippe Lechat, Alexandre Barna, Laurent Becquemont, Jean-François Bergman, Corine Bernaud, Isabelle Boucot, Isabelle Cheiney, Michel Cucherat, Anne d’Andon, Jérôme d’Enfert, Alain Francillon, Elisabeth Frauger, Danièle Girault, Jean-Marc Harlin, Alain Joseph, Catherine Lassale, Florence Mahlberg-Gaudin, Thierry Moreau-Defarges, Mira Pavlovic, Sophie Ravoire, Lise Rochaix, Eric Vicaut
Publikováno v:
Therapies. 65:323-328
Resume La comparaison est un fondement de l’evaluation du medicament. Se pose des lors le probleme du choix du comparateur de tout nouveau traitement, ce d’autant plus qu’existent de larges disparites des pratiques medicales et des conditions d
Autor:
Bruno Falissard, Myriam Zylberman, Michel Cucherat, Valérie Izard, François Meyer, Alexandre Barna, Frédéric De Bels, Rima de Sahb, Jean Delonca, Pascale Jolliet, Jean-Michel Joubert, Robert Launois, Claire Le Jeunne, Michel Lièvre, Florence Mahlberg Gaudin, Aurélie Moser, Patricia Perles, Martine Pigeon, Cécile Rey Coquais, Nadine Weisslinger, Bertrand Xerri
Publikováno v:
Therapies. 64:225-228
Resume Les donnees cliniques soumises au Comite des Medicaments a Usage Humain (CHMP) pour autorisation de mise sur le marche manquent frequemment de comparaisons directes pertinentes des produits. Ces comparaisons peuvent permettre aux autorites nat
Autor:
Bruno Falissard, Myriam Zylberman, Michel Cucherat, Valérie Izard, François Meyer, Alexandre Barna, Frédéric De Bels, Rima de Sahb, Jean Delonca, Pascale Jolliet, Jean-Michel Joubert, Robert Launois, Claire Le Jeunne, Michel Lièvre, Florence Mahlberg Gaudin, Aurélie Moser, Patricia Perles, Martine Pigeon, Cécile Rey Coquais, Nadine Weisslinger, Bertrand Xerri
Publikováno v:
Therapies. 64:229-232
Frequently, in data packages submitted for Marketing Approval to the CHMP, there is a lack of relevant head-to- head comparisons of medicinal products that could enable national authorities responsible for the approval of reimbursement to assess the
Autor:
Eduard I. Dedkov, Wei Zheng, Robert M. Weiss, Lance P. Christensen, Robert J. Tomanek, Florence Mahlberg-Gaudin
Publikováno v:
European Heart Journal. 28:497-723
Autor:
Lance P. Christensen, Wei Zheng, Eduard I. Dedkov, Robert M. Weiss, Robert J. Tomanek, Florence Mahlberg-Gaudin
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H590-H598
We tested the hypothesis that chronically reducing the heart rate in infarcted middle-aged rats using ivabradine (IVA) would induce arteriolar growth and attenuate perivascular collagen and, thereby, improve maximal perfusion and coronary reserve in
Autor:
Lance P. Christensen, Florence Mahlberg-Gaudin, Eduard I. Dedkov, Robert M. Weiss, Wei Zheng, Robert J. Tomanek
Publikováno v:
The FASEB Journal. 21
We tested the hypothesis that heart rate reduction induced in middle-aged post-MI rats can improve perfusion in the surviving LV myocardium by attenuating periarteriolar fibrosis. MI was induced in...