Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Florence Lim"'
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 9, Pp 100605- (2024)
The occurrence of hyperuricemia (HUA; elevated serum uric acid) in athletes is relatively high despite that exercise can potentially reduce the risk of developing this condition. Although recent studies have shown the beneficial properties of DAG in
Externí odkaz:
https://doaj.org/article/a9aac07651e2436fbb1a5a6dadac35d7
Autor:
Gemma Cadby, Corey Giles, Phillip E. Melton, Kevin Huynh, Natalie A. Mellett, Thy Duong, Anh Nguyen, Michelle Cinel, Alex Smith, Gavriel Olshansky, Tingting Wang, Marta Brozynska, Mike Inouye, Nina S. McCarthy, Amir Ariff, Joseph Hung, Jennie Hui, John Beilby, Marie-Pierre Dubé, Gerald F. Watts, Sonia Shah, Naomi R. Wray, Wei Ling Florence Lim, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Tenielle Porter, Michael Vacher, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Kevin Taddei, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J. Saykin, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, John Blangero, Peter J. Meikle, Eric K. Moses
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Dysregulation of lipid metabolism is associated with coronary artery disease (CAD). Here, the authors perform GWAS of the serum lipidome to identify variants associated with lipid species that are putatively in the mechanistic pathway to CAD.
Externí odkaz:
https://doaj.org/article/1160229aa3d04cc8a6b15b682b0f47a7
Autor:
Kevin Huynh, Wei Ling Florence Lim, Corey Giles, Kaushala S. Jayawardana, Agus Salim, Natalie A. Mellett, Adam Alexander T. Smith, Gavriel Olshansky, Brian G. Drew, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, Peter J. Meikle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The onset and pathology of Alzheimer’s disease (AD) is associated with changes to lipid metabolism. Here, the authors analysed 569 lipids from 32 classes and subclasses in two independent patient cohorts to identify key lipid pathways to link the p
Externí odkaz:
https://doaj.org/article/4dd529924c75463b9ab9f71c074acad6
Autor:
Nelson Siu Kei Lam, Xin Xin Long, Xuegang Li, Mirette Saad, Florence Lim, James CG Doery, Robert C. Griffin, Cherrie Galletly
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112541- (2022)
Objectives: To examine the strengths and limitations of existing data to provide guidance for the use of folate supplements as treatment, with or without other psychotropic medications, in various psychiatric disorders. To identify area for further r
Externí odkaz:
https://doaj.org/article/a921d503ad664521b66e2e51a52e1324
Autor:
Giulio D’Acunto, Rosemary Jones, Lucía Pérez Ramírez, Payam Shayesteh, Esko Kokkonen, Foqia Rehman, Florence Lim, Fabrice Bournel, Jean-Jacques Gallet, Rainer Timm, Joachim Schnadt
Publikováno v:
The Journal of Physical Chemistry C. 126:12210-12221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::640d46e85475658da0c2aa6b04350f69
https://doi.org/10.1021/acs.jpcc.2c02683
https://doi.org/10.1021/acs.jpcc.2c02683
Autor:
Adam Alexander T. Smith, Christopher C. Rowe, Andrew J. Saykin, Rebecca Baillie, Brian G. Drew, Matthias Arnold, Wei Ling Florence Lim, Xianlin Han, Gavriel Olshansky, Victor L. Villemagne, Corey Giles, Natalie A. Mellett, Ashley I. Bush, Rima Kaddurah-Daouk, Peter J. Meikle, Ralph N. Martins, Agus Salim, Simon M. Laws, Pratishtha Chatterjee, Kevin Huynh, Kaushala S. Jayawardana, David Ames, Ian Martins, Colin L. Masters, Kwangsik Nho
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nat. Commun. 11:5698 (2020)
Nature Communications
Nat. Commun. 11:5698 (2020)
Nature Communications
Changes to lipid metabolism are tightly associated with the onset and pathology of Alzheimer’s disease (AD). Lipids are complex molecules comprising many isomeric and isobaric species, necessitating detailed analysis to enable interpretation of bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c5b3e38a444a6d2835280c1c346361
https://doaj.org/article/4dd529924c75463b9ab9f71c074acad6
https://doaj.org/article/4dd529924c75463b9ab9f71c074acad6
Autor:
Kaj Blennow, Stephanie J. Fuller, Hamid R. Sohrabi, Yunqi Wu, Tejal M. Shah, Ralph N. Martins, Steve Pedrini, Pratishtha Chatterjee, Cintia B. Dias, Kevin Taddei, Eugene Hone, Heidi Hillebrandt, Kathryn Goozee, Wei Ling Florence Lim, Matthew J. McKay, Prita R. Asih, Preeti Dave, Atul Bhatnagar, Ian Martins, Yeo-Jin Cheong, Victor L. Villemagne, Sunil Gupta, Michelle Tegg, Henrik Zetterberg
Publikováno v:
Journal of Neurochemistry. 159:389-402
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that currently has no cure. Identifying biochemical changes associated with neurodegeneration prior to symptom onset, will provide insight into the biological mechanisms associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc61b4fc011f8f8842a7ea225a84c10
https://doi.org/10.1111/jnc.15128
https://doi.org/10.1111/jnc.15128
Autor:
Corey Giles, Ashley I. Bush, David Ames, Ian Martins, Victor L. Villemagne, Kevin Huynh, Kaushala S. Jayawardana, Christopher C. Rowe, Colin L. Masters, Brian G. Drew, Wei Ling Florence Lim, Simon M. Laws, Natalie A. Mellett, Peter J. Meikle, Ralph N. Martins, Pratishtha Chatterjee
Publikováno v:
Journal of Alzheimer's Disease
Background Lipid metabolism is altered in Alzheimer's disease (AD); however, the relationship between AD risk factors (age, APOEɛ4, and gender) and lipid metabolism is not well defined. Objective We investigated whether altered lipid metabolism asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b8f4f5c168626d5ea5c18870dec5d5
https://doi.org/10.3233/jad-191304
https://doi.org/10.3233/jad-191304
Autor:
Tingting Wang, Kevin Huynh, Corey Giles, Wei Ling Florence Lim, Thy Duong, Natalie A. Mellett, Alexander Smith, Gavriel Olshansky, Brian G. Drew, Gemma Cadby, Phillip E. Melton, Joseph Hung, John Beilby, Gerald F. Watts, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Ralph N. Martins, Eric Moses, Rima F. Kaddurah‐Daouk, Peter J Meikle
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2363bb9b8ada80a0baf4cb3f92bb6077
https://doi.org/10.1002/alz.056703
https://doi.org/10.1002/alz.056703
Autor:
Tingting Wang, Kevin Huynh, Corey Giles, Natalie A Mellett, Thy Duong, Anh Nguyen, Wei Ling Florence Lim, Alex AT Smith, Gavriel Olshansky, Gemma Cadby, Joseph Hung, Jennie Hui, John Beilby, Gerald F Watts, Pratishtha Chatterjee, Ian Martins, Simon M Laws, Ashley I Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Kevin Taddei, Vincent Doré, Jürgen Fripp, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J Saykin, Rebecca Baillie, Xianlin Han, Ralph N Martins, Eric K Moses, Rima Kaddurah‐Daouk, Peter J Meikle
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES. 18(11)
The apolipoprotein E (APOE) genotype is the strongest genetic risk factor for late-onset Alzheimer's disease. However, its effect on lipid metabolic pathways, and their mediating effect on disease risk, is poorly understood.We performed lipidomic ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cfc8d4a37b17f060369aec008a8bf9
https://pubmed.ncbi.nlm.nih.gov/35077012
https://pubmed.ncbi.nlm.nih.gov/35077012