Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Florence Levillain"'
Autor:
Alexia Dumas, Dan Corral, André Colom, Florence Levillain, Antonio Peixoto, Denis Hudrisier, Yannick Poquet, Olivier Neyrolles
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Tuberculosis (TB), caused by the airborne bacterial pathogen Mycobacterium tuberculosis, remains a major source of morbidity and mortality worldwide. So far, the study of host-pathogen interactions in TB has mostly focused on the physiology and virul
Externí odkaz:
https://doaj.org/article/6254d4ed8b4c4acbaf916c408f4a345c
Autor:
Florence Levillain, Yannick Poquet, Ludovic Mallet, Serge Mazères, Michael Marceau, Roland Brosch, Franz-Christoph Bange, Philip Supply, Axel Magalon, Olivier Neyrolles
Publikováno v:
PLoS Pathogens, Vol 13, Iss 11, p e1006752 (2017)
The unique ability of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, to persist for long periods of time in lung hypoxic lesions chiefly contributes to the global burden of latent TB. We and others previously reported that the M. tubercu
Externí odkaz:
https://doaj.org/article/536308e030dc437aa49d1babdfdc9a73
Autor:
Alexandre Gouzy, Gérald Larrouy-Maumus, Daria Bottai, Florence Levillain, Alexia Dumas, Joshua B Wallach, Irène Caire-Brandli, Chantal de Chastellier, Ting-Di Wu, Renaud Poincloux, Roland Brosch, Jean-Luc Guerquin-Kern, Dirk Schnappinger, Luiz Pedro Sório de Carvalho, Yannick Poquet, Olivier Neyrolles
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003928 (2014)
Mycobacterium tuberculosis is an intracellular pathogen. Within macrophages, M. tuberculosis thrives in a specialized membrane-bound vacuole, the phagosome, whose pH is slightly acidic, and where access to nutrients is limited. Understanding how the
Externí odkaz:
https://doaj.org/article/ab8fb567ac654e6b8e1dc58688fb2b26
Autor:
Kang Wu, Dandan Dong, Hai Fang, Florence Levillain, Wen Jin, Jian Mei, Brigitte Gicquel, Yanzhi Du, Kankan Wang, Qian Gao, Olivier Neyrolles, Ji Zhang
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38367 (2012)
The W-Beijing family of Mycobacterium tuberculosis (Mtb) strains is known for its high-prevalence and -virulence, as well as for its genetic diversity, as recently reported by our laboratories and others. However, little is known about how the immune
Externí odkaz:
https://doaj.org/article/6874ebb86f7d42cb8678b48832cf3c92
Autor:
Priscille Brodin, Yannick Poquet, Florence Levillain, Isabelle Peguillet, Gerald Larrouy-Maumus, Martine Gilleron, Fanny Ewann, Thierry Christophe, Denis Fenistein, Jichan Jang, Mi-Seon Jang, Sei-Jin Park, Jean Rauzier, Jean-Philippe Carralot, Rachel Shrimpton, Auguste Genovesio, Jesus A Gonzalo-Asensio, Germain Puzo, Carlos Martin, Roland Brosch, Graham R Stewart, Brigitte Gicquel, Olivier Neyrolles
Publikováno v:
PLoS Pathogens, Vol 6, Iss 9, p e1001100 (2010)
The ability of the tubercle bacillus to arrest phagosome maturation is considered one major mechanism that allows its survival within host macrophages. To identify mycobacterial genes involved in this process, we developed a high throughput phenotypi
Externí odkaz:
https://doaj.org/article/3fbdc7f8e69e49e48b8fb602f57de815
Autor:
Pascale Peyron, Julien Vaubourgeix, Yannick Poquet, Florence Levillain, Catherine Botanch, Fabienne Bardou, Mamadou Daffé, Jean-François Emile, Bruno Marchou, Pere-Joan Cardona, Chantal de Chastellier, Frédéric Altare
Publikováno v:
PLoS Pathogens, Vol 4, Iss 11, p e1000204 (2008)
Tuberculosis (TB) is characterized by a tight interplay between Mycobacterium tuberculosis and host cells within granulomas. These cellular aggregates restrict bacterial spreading, but do not kill all the bacilli, which can persist for years. In-dept
Externí odkaz:
https://doaj.org/article/a5a673a2487e452ea251c94b02cd0366
Autor:
Yannick Poquet, Jean-Charles Guéry, Tamara Sneperger, Denis Hudrisier, Florence Levillain, Dan Corral, Matthew R. Hepworth, Rafael J. Argüello, Emma Lefrançais, Gérard Eberl, Alison Charton, Olivier Neyrolles, Eve Blanquart, Jean-Philippe Girard, Maria Z Krauss
Tissue-resident innate lymphoid cells (ILCs) regulate tissue homeostasis, protect against pathogens at mucosal surfaces and are key players at the interface of innate and adaptive immunity. How ILCs adapt their phenotype and function to environmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb6142953070b34efb41b99c974bea0
https://hal.science/hal-03451521
https://hal.science/hal-03451521
Autor:
Dan Corral, Alison Charton, Maria Z. Krauss, Eve Blanquart, Florence Levillain, Emma Lefrançais, Tamara Sneperger, Zoï Vahlas, Jean-Philippe Girard, Gérard Eberl, Yannick Poquet, Jean-Charles Guéry, Rafael J. Argüello, Yasmine Belkaid, Katrin D. Mayer-Barber, Matthew R. Hepworth, Olivier Neyrolles, Denis Hudrisier
Publikováno v:
Cell Reports
Cell Reports, 2022, 39, ⟨10.1016/j.celrep.2022.110715⟩
Cell Reports, 2022, 39, ⟨10.1016/j.celrep.2022.110715⟩
Tissue-resident innate lymphoid cells (ILCs) regulate tissue homeostasis, protect against pathogens at mucosal surfaces, and are key players at the interface of innate and adaptive immunity. How ILCs adapt their phenotype and function to environmenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91320ac5f1bcfe60ca23dc5218e91482
https://pubmed.ncbi.nlm.nih.gov/35443177
https://pubmed.ncbi.nlm.nih.gov/35443177
Autor:
Dan Corral, Florence Levillain, Olivier Neyrolles, Emma Lefrançais, Gérard Eberl, Yannick Poquet, Denis Hudrisier, Matthew R. Hepworth, Jean-Charles Guéry, Eve Blanquart, Jean-Philippe Girard, Alison Charton, Rafael J. Argüello, Maria Z Krauss
Publikováno v:
SSRN Electronic Journal.
Tissue-resident innate lymphoid cells (ILCs) regulate tissue homeostasis and protect against pathogens at mucosal surfaces and are key players at the interface of innate and adaptive immunity. How ILCs adapt their phenotype and function to environmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e569b68f052cebcde629266d8a4349f6
https://doi.org/10.2139/ssrn.3787899
https://doi.org/10.2139/ssrn.3787899
Autor:
Priscille Brodin, Christophe Guilhot, Simon Clark, Sung Jae Shin, Olivier Neyrolles, Florence Levillain, Felipe Cia, Wladimir Malaga, Gregory J. Bancroft, Hongmin Kim, Yannick Poquet, Ann Williams, Brigitte Gicquel, Kee Woong Kwon, Faye Lanni
Publikováno v:
Vaccine
Vaccine, Elsevier, 2020, 38 (6), pp.1416-1423. ⟨10.1016/j.vaccine.2019.11.085⟩
Vaccine, Elsevier, 2020, 38 (6), pp.1416-1423. ⟨10.1016/j.vaccine.2019.11.085⟩
Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e7ab780b4eb596c571468448cda351
https://hal.archives-ouvertes.fr/hal-03014488
https://hal.archives-ouvertes.fr/hal-03014488