Výsledky vyhledávání - "Florence Jaouen"

Akademický článek

Optimized miR-124 reporters uncover differences in miR-124 expression among neuronal populations in vitro

Autor: Catherine Lepolard, Cynthia Rombaut, Florence Jaouen, Ana Borges, Elodie Caccomo-Garcia, Natalia Popa, Eduardo Gascon

Publikováno v: Frontiers in Neuroscience, Vol 17 (2023)

IntroductionAlthough intensively studied in the last decades, how microRNAs (miRNAs) are expressed across different cell types in the brain remains largely unknown.MaterialsTo address this issue, we sought to develop optimized fluorescence reporters

Externí odkaz: https://doaj.org/article/c240636e4d254b0e9cc4cbab7abb2b86

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Akademický článek

Social Isolation and Enrichment Induce Unique miRNA Signatures in the Prefrontal Cortex and Behavioral Changes in Mice

Autor: Natalia Popa, Flora Boyer, Florence Jaouen, Raoul Belzeaux, Eduardo Gascon

Publikováno v: iScience, Vol 23, Iss 12, Pp 101790- (2020)

Summary: An extensive body of evidence supports the notion that exposure to an enriched/impoverished environment alters brain functions via epigenetic changes. However, how specific modifications of social environment modulate brain functions remains

Externí odkaz: https://doaj.org/article/606fe11d7ec6442a82eb9fc70f6487b3

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Akademický článek

Deficits in Social Behavior Precede Cognitive Decline in Middle-Aged Mice

Autor: Flora Boyer, Florence Jaouen, El Chérif Ibrahim, Eduardo Gascon

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 13 (2019)

An extensive literature details deterioration of multiple brain functions, especially memory and learning, during aging in humans and in rodents. In contrast, the decline of social functions is less well understood. It is presently not clear whether

Externí odkaz: https://doaj.org/article/f6bdae8af813446e9a833b279eccbc55

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Akademický článek

Striatal Cholinergic Interneurons Control Motor Behavior and Basal Ganglia Function in Experimental Parkinsonism

Autor: Nicolas Maurice, Martine Liberge, Florence Jaouen, Samira Ztaou, Marwa Hanini, Jeremy Camon, Karl Deisseroth, Marianne Amalric, Lydia Kerkerian-Le Goff, Corinne Beurrier

Publikováno v: Cell Reports, Vol 13, Iss 4, Pp 657-666 (2015)

Despite evidence showing that anticholinergic drugs are of clinical relevance in Parkinson’s disease (PD), the causal role of striatal cholinergic interneurons (CINs) in PD pathophysiology remains elusive. Here, we show that optogenetic inhibition

Externí odkaz: https://doaj.org/article/c82b82e2e05d4df882373fa1b3b08b68

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Prise en charge d’un patient adulte atteint de mucoviscidose

Autor: Pierre Senesse, Davide Caimmi, Nicolas Flori, Romain Altwegg, Raphaël Chiron, Florence Jaouen, Françoise Marquez

Publikováno v: Nutrition Clinique et Métabolisme. 32:90-94

La consommation d'algues alimentaires se developpe en Europe et particulierement en France ou il macroalgues ont ete autorisees par le Conseil Superieur de l'Hygiene Publique. La forte teneur en polysaccharides parietaux de ces vegetaux contribue a l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::915fdb2ceb392cfae25b63dd4076c757
https://doi.org/10.1016/j.nupar.2018.02.002

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SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation

Autor: Zong-Bo Wei, Wei Li, Zengqiang Yuan, Corinne Beurrier, Chanjuan Hao, Zhe Zhang, Li Yu, Florence Jaouen, Meisheng Ma, Yefeng Yuan, Quan Chen

Publikováno v: Autophagy
Autophagy, Taylor & Francis, 2016, 12 (7), pp.1168-1179. ⟨10.1080/15548627.2016.1179402⟩
Autophagy, 2016, 12 (7), pp.1168-1179. ⟨10.1080/15548627.2016.1179402⟩

International audience; Searching for new regulators of autophagy involved in selective dopaminergic (DA) neuron loss is a hallmark in the pathogenesis of Parkinson disease (PD). We here report that an endoplasmic reticulum (ER)-associated transmembr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0388d1c1d4c01f29863735157a49a82d
https://hal.archives-ouvertes.fr/hal-03079432

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Understanding the role of miR-33 in brain lipid metabolism: implications for Alzheimer's disease

Autor: Eduardo Gascon, Florence Jaouen

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2016, 36 (9), pp.2558-2560. ⟨10.1523/JNEUROSCI.4571-15.2016⟩
Journal of Neuroscience, 2016, 36 (9), pp.2558-2560. ⟨10.1523/JNEUROSCI.4571-15.2016⟩

Dysregulation of amyloid-β (Aβ) metabolism is critical for Alzheimer's disease (AD) pathogenesis. Mounting evidence suggests that apolipoprotein E (ApoE) is involved in Aβ metabolism. ATP-binding cassette transporter A1 (ABCA1) is a key regulator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5746699118ca266c9f44c3ebe985ec
https://hal-amu.archives-ouvertes.fr/hal-01464467

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A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells

Autor: Florence Jaouen, Pascale Durbec, Mehdi Saadaoui, Xavier Morin, Laurence Haren, Andreas Merdes, Elise Peyre

Publikováno v: The Journal of Cell Biology

Knockdown or mislocalization of LGN complex components disrupts the stereotypic biphasic spindle movements regulating planar cell division and neuroepithelial structure in chick embryos.
To maintain tissue architecture, epithelial cells divide i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f1424e9c662bde4fec652c5bced753
https://doi.org/10.1083/jcb.201101039

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Cellular and Behavioral Outcomes of Dorsal Striatonigral Neuron Ablation: New Insights into Striatal Functions

Autor: Dorian Chabbert, Marianne Amalric, Hélène Marie, Pascal Salin, Lydia Kerkerian-Le Goff, Lena Concetta, Christophe Melon, Elisiana Tafi, Francina Langa, Corinne Beurrier, Delphine Révy, Florence Jaouen

Publikováno v: Neuropsychopharmacology
Neuropsychopharmacology, Nature Publishing Group, 2014, 39 (11), pp.2662-2672. ⟨10.1038/npp.2014.121⟩
Neuropsychopharmacology, Nature Publishing Group, 2014, 39 (11), pp.2662-72. ⟨10.1038/npp.2014.121⟩
Neuropsychopharmacology, 2014, 39 (11), pp.2662-2672. ⟨10.1038/npp.2014.121⟩

International audience; The striatum is the input structure of the basal ganglia network that contains heterogeneous neuronal populations, including two populations of projecting neurons called the medium spiny neurons (MSNs), and different types of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c60c7129f37e8029056cf18a510b78
https://europepmc.org/articles/PMC4207346/

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Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium

Autor: Xavier Morin, Florence Jaouen, Pascale Durbec

Publikováno v: Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2007, 10, pp.1440-1448
Nature Neuroscience, 2007, 10, pp.1440-1448

The spatio-temporal regulation of symmetrical as opposed to asymmetric cell divisions directs the fate and location of cells in the developing CNS. In invertebrates, G-protein regulators control spindle orientation in asymmetric divisions, which gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423d5dd9e979a133af89ee400690f3c1
https://hal.archives-ouvertes.fr/hal-00306564

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