Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Florence J. Hardy"'
Autor:
Amy E. Hutton, Jake Foster, Rebecca Crawshaw, Florence J. Hardy, Linus O. Johannissen, Thomas M. Lister, Emilie F. Gérard, Zachary Birch-Price, Richard Obexer, Sam Hay, Anthony P. Green
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Directed evolution of computationally designed enzymes has provided new insights into the emergence of sophisticated catalytic sites in proteins. In this regard, we have recently shown that a histidine nucleophile and a flexible arginine can
Externí odkaz:
https://doaj.org/article/44c22094b4a04ee98c938f54110c8603
Autor:
Mary Ortmayer, Florence J. Hardy, Matthew G. Quesne, Karl Fisher, Colin Levy, Derren J. Heyes, C. Richard A. Catlow, Sam P. de Visser, Stephen E. J. Rigby, Sam Hay, Anthony P. Green
Publikováno v:
JACS Au, Vol 1, Iss 7, Pp 913-918 (2021)
Externí odkaz:
https://doaj.org/article/7b1ea1dfa43042aa99a9e11ae0aa8261
Autor:
Elizabeth L. Bell, Ross Smithson, Siobhan Kilbride, Jake Foster, Florence J. Hardy, Saranarayanan Ramachandran, Aleksander A. Tedstone, Sarah J. Haigh, Arthur A. Garforth, Philip J. R. Day, Colin Levy, Michael P. Shaver, Anthony P. Green
Publikováno v:
Nature Catalysis. 5:673-681
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7e1d2020fa56daaf4656cb9e083de41
https://doi.org/10.1038/s41929-022-00821-3
https://doi.org/10.1038/s41929-022-00821-3
Autor:
Christopher J. Taylor, Florence J. Hardy, Ashleigh J. Burke, Riley M. Bednar, Ryan A. Mehl, Anthony P. Green, Sarah L. Lovelock
Publikováno v:
Protein Science. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa165f3dd625495ca63c85265ef46b3
https://doi.org/10.1002/pro.4640
https://doi.org/10.1002/pro.4640
Autor:
Jonathan S. Trimble, Rebecca Crawshaw, Florence J. Hardy, Colin W. Levy, Murray J. B. Brown, Douglas E. Fuerst, Derren J. Heyes, Richard Obexer, Anthony P. Green
Publikováno v:
Trimble, J, Crawshaw, R, Hardy, F, Levy, C, Brown, M J B, Fuerst, D E, Heyes, D, Obexer, R & Green, A 2022, ' A Designed Photoenzyme for Enantioselective [2+2]-Cycloadditions ', Nature., vol. 611, no. 7937 . https://doi.org/10.1038/s41586-022-05335-3
The ability to programme new modes of catalysis into proteins would allow the development of enzyme families with functions beyond those found in nature. To this end, genetic code expansion methodology holds particular promise, as it allows the site-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed299e8a23e39f23f13dd65b4bdded8
https://pubmed.ncbi.nlm.nih.gov/36130727
https://pubmed.ncbi.nlm.nih.gov/36130727
Autor:
Matthew G. Quesne, Florence J. Hardy, Stephen E. J. Rigby, Sam Hay, C. Richard A. Catlow, Sam P. de Visser, Karl Fisher, Colin Levy, Anthony P. Green, Derren J. Heyes, Mary Ortmayer
Publikováno v:
JACS Au, Vol 1, Iss 7, Pp 913-918 (2021)
JACS Au
JACS Au
Nature employs high-energy metal-oxo intermediates embedded within enzyme active sites to perform challenging oxidative transformations with remarkable selectivity. Understanding how different local metal-oxo coordination environments control interme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea5cd79aab625181d24c7a852691fc9
https://orca.cardiff.ac.uk/id/eprint/143856/1/jacsau.1c00145.pdf
https://orca.cardiff.ac.uk/id/eprint/143856/1/jacsau.1c00145.pdf
Publikováno v:
Comprehensive Coordination Chemistry III ISBN: 9780081026892
Comprehensive Coordination Chemistry III
Comprehensive Coordination Chemistry III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::571388c9b5c3cf45971b39292e4dcfdc
https://doi.org/10.1016/b978-0-08-102688-5.00021-0
https://doi.org/10.1016/b978-0-08-102688-5.00021-0