Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Florence Hallouin"'
Autor:
Jacques Le Pendu, Caroline Goupille, Séverine Marionneau, Jézabel Rocher, Florence Hallouin, Béatrice Vaydie, Valérie Bureau
Publikováno v:
International Journal of Cancer. 86:713-717
The presence of α1,2-fucosylated glycans at the surface of rat colon carcinoma cells has been associated with an increased tumorigenicity and resistance to natural killer/lymphokine activated killer (NK/LAK) cytotoxicity. We now report that transfec
Publikováno v:
International Journal of Cancer. 80:606-611
Accumulation of histo-blood group antigens such as Lewis b, Lewis Y and H increases tumor cell motility and tumorigenesis. α1,2-Fucosylation is a key step in the synthesis of these antigens. Two α1,2-fucosyltransferases, expressed in colorectal car
Publikováno v:
Glycoconjugate Journal. 16:681-684
Clones either strongly or barely expressing the Tn and Sialyl-Tn antigens were isolated from a rat colon carcinoma cell line. Expression of the antigens in normal rat tissues was very restricted and vaccination using Ovine Submaxillary Mucin as the i
Publikováno v:
International Journal of Cancer. 76:136-140
Up-regulation of the synthesis of carbohydrate tumor-associated antigens terminated by the disaccharide Fucα1-2Gal is frequent in colon carcinoma and associated with poor prognosis. There is evidence that Fucα1-2Gal (H-disaccharide) structures incr
Publikováno v:
Glycoconjugate Journal. 14:801-808
Using an experimental model of rat colon adenocarcinoma, we have recently shown that the presence of H blood-group antigen on variants of the CD44 adhesion molecule carrying amino acids encoded by exon v6 (CD44v6), increased the cells' tumorigenicity
Publikováno v:
Glycobiology. 7:221-229
Fucosylated histo-blood group antigens such as Lewis b, Lewis Y, and H accumulate in colon carcinoma and this is accompanied by a clear increase in alpha(1-2)fucosyltransferase activity, a key enzyme for the biosynthesis of these antigens. Yet the bi
Autor:
Jézabel Rocher, Caroline Goupille, Séverine Marionneau, Valérie Bureau, Jacques Le Pendu, Marc Meichenin, Florence Hallouin
Publikováno v:
Glycobiology. 10(4)
Accumulation of histo-blood group antigens such as Lewis b, Lewis Y and H in colon cancer is indicative of poor prognosis. It is accompanied by increase in alpha1,2fucosyl-transferase activity, a key enzyme for synthesis of these antigens. Using a mo
Publikováno v:
International Journal of Cancer. 85:142
5-Fluorouracil (5-FU) is a drug of standard use in chemotherapy of colon carcinoma. However, its efficacy is limited by inherent and acquired cell resistance. Major changes in histo-blood group antigenic expression, at times associated with poor prog