D-myo-inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation

Autor: Audrey Michaud, Françoise Chrétien, Cyril Goudet, Jean-Philippe Pin, Hervé Ansanay, Florence Grillet, Cédric Leroy, Yves Chapleur, Fanny Malhaire, Gérard Mathis, Fabrice Maurin, Emmanuel Bourrier, Olivier Hernout, Damien Maurel, Michel Fink, Thierry Durroux, Magali Naval, Eric Trinquet, Herve Bazin

Publikováno v: Analytical Biochemistry
Analytical Biochemistry, Elsevier Masson, 2006, 358 (1), pp.126-35. ⟨10.1016/j.ab.2006.08.002⟩
Analytical Biochemistry, 2006, 358 (1), pp.126-35. ⟨10.1016/j.ab.2006.08.002⟩

International audience; Phospholipase C beta (PLC-beta)-coupled G protein-coupled receptor (GPCR) activities traditionally are assessed by measuring Ca2+ triggered by D-myo-inositol 1,4,5-trisphosphate (IP3), a PLC-beta hydrolysis product, or by meas

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https://www.hal.inserm.fr/inserm-00318996