Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Florence Geiguer"'
Autor:
Emmanuel Grolleau, Julie Candiracci, Gaelle Lescuyer, David Barthelemy, Nazim Benzerdjeb, Christine Haon, Florence Geiguer, Margaux Raffin, Nathalie Hardat, Julie Balandier, Rémi Rabeuf, Lara Chalabreysse, Anne-Sophie Wozny, Guillaume Rommelaere, Claire Rodriguez-Lafrasse, Fabien Subtil, Sébastien Couraud, Marielle Herzog, Lea Payen-Gay
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1255 (2023)
The molecular profiling of circulating tumor DNA (ctDNA) is a helpful tool not only in cancer treatment, but also in the early detection of relapse. However, the clinical interpretation of a ctDNA negative result remains challenging. The characteriza
Externí odkaz:
https://doaj.org/article/e39cda56d70240f48db2b0d280f75cff
Autor:
Jessica Garcia, Nick Kamps-Hughes, Florence Geiguer, Sébastien Couraud, Brice Sarver, Léa Payen, Cristian Ionescu-Zanetti
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Circulating cell-free DNA (cfDNA) has the potential to be a specific biomarker for the therapeutic management of lung cancer patients. Here, a new sequencing error-reduction method based on molecular amplification pools (MAPs) was utilized t
Externí odkaz:
https://doaj.org/article/da8aee7bdc1c403a8d63c53a6d8142ba
Autor:
Jessica Garcia, Anne‐Sophie Wozny, Florence Geiguer, Aurélia Delherme, David Barthelemy, Patrick Merle, Claire Tissot, Frederick S. Jones, Chassidy Johnson, Xiaobin Xing, Zhenyu Xu, Daniel L. Edelstein, Marie Brevet, Pierre‐Jean Souquet, Claire Rodriguez‐Lafrasse, Léa Payen, Sébastien Couraud
Publikováno v:
Cancer Medicine, Vol 8, Iss 8, Pp 3685-3697 (2019)
Abstract Cell‐free plasma DNA (cfDNA) and mimicking circulating tumor cells (mCTCs) have demonstrated tremendous potential for molecular diagnosis of cancer and have been rapidly implemented in specific settings. However, widespread clinical adopti
Externí odkaz:
https://doaj.org/article/7a9999a583fd4631af8c0d011cb7254c
Autor:
David Barthelemy, Gaelle Lescuyer, Florence Geiguer, Emmanuel Grolleau, Arnaud Gauthier, Julie Balandier, Margaux Raffin, Claire Bardel, Bruno Bouyssounouse, Claire Rodriguez-Lafrasse, Sébastien Couraud, Anne-Sophie Wozny, Léa Payen
Publikováno v:
Cancers
Volume 15
Issue 5
Pages: 1574
Volume 15
Issue 5
Pages: 1574
Introduction: Progressive advanced non-small cell lung cancer (NSCLC) accounts for about 80–85% of all lung cancers. Approximately 10–50% of patients with NSCLC harbor targetable activating mutations, such as in-frame deletions in Exon 19 (Ex19de
Autor:
Xavier Rousset, Denis Maillet, Emmanuel Grolleau, David Barthelemy, Sara Calattini, Marie Brevet, Julie Balandier, Margaux Raffin, Florence Geiguer, Jessica Garcia, Myriam Decaussin-Petrucci, Julien Peron, Nazim Benzerdjeb, Sébastien Couraud, Jean Viallet, Léa Payen
Publikováno v:
Cancers; Volume 14; Issue 17; Pages: 4085
Patient-Derived Xenografts (PDXs) in the Chorioallantoic Membrane (CAM) are a representative model for studying human tumors. Circulating Tumor Cells (CTCs) are involved in cancer dissemination and treatment resistance mechanisms. To facilitate resea
Autor:
Sébastien Couraud, Léa Payen, Brice Sarver, Cristian Ionescu-Zanetti, Nick Kamps-Hughes, Jessica Garcia, Florence Geiguer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Circulating cell-free DNA (cfDNA) has the potential to be a specific biomarker for the therapeutic management of lung cancer patients. Here, a new sequencing error-reduction method based on molecular amplification pools (MAPs) was utilized to analyze
Autor:
Emmanuel Grolleau, Julie Candiracci, Arnaud Gauthier, Gaelle Lescuyer, David Barthelemy, Christine Haon, Florence Geiguer, Margaux Raffin, Nathalie Hardat, Julie Balandier, Rémi Rabeuf, Anne-Sophie Wozny, Guillaume Rommelaere, Claire Rodriguez-Lafrasse, Fabien Subtil, Sébastien Couraud, Marielle Herzog, Lea Payen-Gay
Publikováno v:
Cancer Research. 83:2163-2163
Introduction: Treatment options of lung cancer (LC) comprise radiotherapy, and/or combined treatment approaches, including chemotherapy, immunotherapy and targeted therapies based on the tumoral molecular profile. Following curative-intent first-line
Autor:
David Barthelemy, Arnaud Vigneron, Xavier Rousset, Jerome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaelle Lescuyer, Florence Geiguer, Sebastien Couraud, Jean Vaillet, Nazim Benzerdjeb, Lea Payen-Gay
Publikováno v:
Cancer Research. 83:4866-4866
Introduction: NSCLC accounts for about 80-85% of all lung cancers. Approximately 10-50% of patients with NSCLC harbor EGFR activating mutations, such as in-frame deletions in exon 19 (Ex19del). Currently, for patients with advanced NSCLC, testing for
Autor:
David Barthelemy, Emmanuel Grolleau, Gaelle Lescuyer, Florence Geiguer, Arnaud Gauthier, Julie Balandier, Margaux Raffin, Claire Bardel, Bruno Bouyssounouse, Claire Rodriguez-Lafrasse, Sébastien Couraud, Anne-Sophie Wozny, Lea Payen-Gay
Publikováno v:
Cancer Research. 83:6691-6691
Background: Noninvasive genotyping using plasma cell-free DNA (cfDNA) has the potential to obviate the need for some invasive biopsies in cancer patients. We sought to validate an ultra-deep plasma Next-Generation Sequencing (NGS) assay for patients
Autor:
Jessica, Garcia, Arnaud, Gauthier, Gaëlle, Lescuyer, David, Barthelemy, Florence, Geiguer, Julie, Balandier, Daniel L, Edelstein, Frederick S, Jones, Frank, Holtrup, Mickael, Duruisseau, Emmanuel, Grolleau, Claire, Rodriguez-Lafrasse, Patrick, Merle, Sébastien, Couraud, Léa, Payen
Publikováno v:
Molecular Diagnosis & Therapy
Background and Objectives The use of ultra-sensitive diagnostic tests to detect clinically actionable somatic alterations within the gene encoding the epidermal growth factor receptor (EGFR) within circulating cell-free DNA is an important first step