Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Florence Emmanuel"'
Autor:
Richard B. Weinberg, Rachel A. Anderson, Victoria R. Cook, Florence Emmanuel, Patrice Denefle, Marcela Hermann, Armin Steinmetz
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 9, Pp 1410-1418 (2000)
To gain insight into the evolution and function of apolipoprotein A-IV (apoA-IV) we compared structural and interfacial properties of chicken apoA-IV, human apoA-IV, and a recombinant human apoA-IV truncation mutant lacking the carboxyl terminus. Cir
Externí odkaz:
https://doaj.org/article/62b5e40b1fba445f9449966036269c51
Autor:
Florence Emmanuel, Abderrahim Mahfoudi, Daniel Scherman, Pia Delaère, Mickaël Bettan, Didier Branelec, Fabienne Soubrier, Jean-Michel Caillaud, Nicolas Duverger, Raphaël Darteil
Publikováno v:
Molecular Therapy. 2:204-210
Numerous diseases are linked to the absence or insufficient concentration of a specific plasma protein. Gene transfer is an appealing strategy for correction of such diseases. We report high and sustained plasma secretion of human secreted alkaline p
Autor:
Eric Bruckert, P. Haydn Pritchard, Paul Cullen, Patrick Benoit, Patrice Denefle, Gerd Assmann, U Daum, Claus Langer, A. Chirazi, Arnold von Eckardstein, Florence Emmanuel, Nicolas Duverger
Publikováno v:
Journal of Molecular Medicine. 77:614-622
ApoA-I(R151)Paris is a natural apolipoprotein (apo) A-I variant that is associated with low levels of high-density lipoprotein cholesterol (HDL-cholesterol) and the partial deficiency of lecithin:cholesterol acyl-transferase (LCAT) in the plasma of h
Autor:
Laurent Bassinet, Jean Michel Caillaud, Patrick Benoit, Graciela Castro, Patrice Denefle, Pierre Gallix, Jean Charles Fruchart, Didier Branellec, Nicolas Duverger, Florence Emmanuel
Publikováno v:
Circulation. 99:105-110
Background —Apolipoprotein (apo) A-I is the major component of HDL, and it displays antiatherogenic properties. Methods and Results —The human apoA-I gene has been transferred into different mouse models by use of a recombinant adenovirus under t
Publikováno v:
Journal of Biological Chemistry. 272:24287-24293
Plasma high density lipoproteins (HDLs) from humans, from transgenic mice to human apolipoprotein A-I (HuAITg mice), from transgenic mice to human apolipoprotein A-II (HuAIITg mice), from transgenic mice to human apolipoproteins A-I and A-II (HuAIAII
Autor:
Laurence Berthou, Didier Branellec, Johan Auwerx, J.C. Fruchart, Bart Staels, A Guillouzo, Florence Emmanuel, Patrice Denefle, Eric J. Rubin, Nicolas Duverger, S Langouët
Publikováno v:
Journal of Clinical Investigation. 97:2408-2416
The regulation of liver apolipoprotein (apo) A-I gene expression by fibrates was studied in human apo A-I transgenic mice containing a human genomic DNA fragment driving apo A-I expression in liver. Treatment with fenofibrate (0.5% wt/wt) for 7 d inc
Autor:
A Steinmetz, R Brasseur, M Rosseneu, J C Fruchart, Florence Emmanuel, F Attenot, S Cuiné, Martine Latta, N Gosselet, S Séguret
Publikováno v:
Journal of Biological Chemistry. 269:29883-29890
To investigate the structure-function relationship of human apolipoprotein A-IV (apoA-IV), several deletion mutants of this protein were constructed by sequentially removing pairs of 22-residue repeats, potentially having an amphipathic alpha-helical
Autor:
Patrice Denefle, Jean-Michel Caillaud, Florence Emmanuel, Graciela Castro, Gunter Tremp, Nicolas Duverger, Armin Steinmetz, Jean-Charles Fruchart
Publikováno v:
Science. 273:966-968
Apolipoproteins are protein constituents of plasma lipid transport particles. Human apolipoprotein A-IV (apoA-IV) was expressed in the liver of C57BL/6 mice and mice deficient in apoE, both of which are prone to atherosclerosis, to investigate whethe
Autor:
Florence Emmanuel, Didier Branellec, Bertrand Schwartz, Pia Delaère, Alexis Caron, Anne Caron, Sandrine Michelet, Sylvie Sordello, Marie-Agnès Ivanov
Publikováno v:
The journal of gene medicine. 6(9)
Background Acidic fibroblast growth factor (FGF-1) has been identified as a potent mitogen for vascular cells, inducing formation of mature blood vessels in vitro and in vivo and represents one of the most promising approaches for the treatment of is
Autor:
Téni G. Ebrahimian, Radia Tamarat, Micheline Duriez, Aude Leroux, Florence Emmanuel, Jean-Sébastien Silvestre, Didier Branellec, Bernard I. Levy, Michel Clergue, Bertrand Schwartz
Publikováno v:
Circulation research. 93(2)
Vascular endothelial growth factors (VEGFs) and their receptors have emerged as central regulators of the angiogenic process. However, involvement of VEGF-B, one of these factors, in angiogenesis remains obscure. Mice received subcutaneous injection