Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Florence E. Perrin"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The glial scar that forms after traumatic spinal cord injury (SCI) is mostly composed of microglia, NG2 glia, and astrocytes and plays dual roles in pathophysiological processes induced by the injury. On one hand, the glial scar acts as a chemical an
Externí odkaz:
https://doaj.org/article/9a1ecb0feee54b149827c9bf079a23c5
Autor:
Gaëtan Poulen, Yannick N Gerber, Jean-Christophe Perez, Khadidja Oubarrahou, Nicolas Lonjon, Florence Vachiery-Lahaye, Hassan Boukhaddaoui, Florence E. Perrin
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Many histological techniques are used to identify and characterize myelin in the mammalian nervous system. Due to the high content of lipids in myelin sheaths, coherent anti-stokes Raman scattering (CARS) microscopy is a label-free method that allows
Externí odkaz:
https://doaj.org/article/1d9071d42c334295a6f61c5259ae21ed
Autor:
Hussein Ghazale, Chantal Ripoll, Nicolas Leventoux, Laurent Jacob, Safa Azar, Daria Mamaeva, Yael Glasson, Charles-Felix Calvo, Jean-Leon Thomas, Sarah Meneceur, Yvan Lallemand, Valérie Rigau, Florence E. Perrin, Harun N. Noristani, Brenda Rocamonde, Emmanuelle Huillard, Luc Bauchet, Jean-Philippe Hugnot
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1159-1177 (2019)
Summary: Anamniotes, rodents, and young humans maintain neural stem cells in the ependymal zone (EZ) around the central canal of the spinal cord, representing a possible endogenous source for repair in mammalian lesions. Cell diversity and genes spec
Externí odkaz:
https://doaj.org/article/705f9ae190674326953c60e1d157bba2
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
In traumatic spinal cord injury, the initial trauma is followed by a cascade of impairments, including excitotoxicity and calcium overload, which ultimately induces secondary damages. The sigma-1 receptor is widely expressed in the central nervous sy
Externí odkaz:
https://doaj.org/article/5bf85e2ed9d244c1af5c2dbd6e06effa
Publikováno v:
Brain Sciences, Vol 11, Iss 12, p 1643 (2021)
Microglia are major players in scar formation after an injury to the spinal cord. Microglia proliferation, differentiation, and survival are regulated by the colony-stimulating factor 1 (CSF1). Complete microglia elimination using CSF1 receptor (CSF1
Externí odkaz:
https://doaj.org/article/2a1ca4be16a0449fa1a891b1ad487562
Autor:
Harun N. Noristani, Hassan Boukhaddaoui, Guillaume Saint-Martin, Pauline Auzer, Rahima Sidiboulenouar, Nicolas Lonjon, Eric Alibert, Nicolas Tricaud, Christophe Goze-Bac, Christophe Coillot, Florence E. Perrin
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Central nervous system (CNS) injury has been observed to lead to microglia activation and monocytes infiltration at the lesion site. Ex vivo diffusion magnetic resonance imaging (diffusion MRI or DWI) allows detailed examination of CNS tissues, and r
Externí odkaz:
https://doaj.org/article/221593b022e349f9911a118294888775
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Over the last decade, microglia have been acknowledged to be key players in central nervous system (CNS) under both physiological and pathological conditions. They constantly survey the CNS environment and as immune cells, in pathological contexts, t
Externí odkaz:
https://doaj.org/article/377d9574fe7c4f10a1781563f29496e9
Autor:
Gaetan Poulen, Florence E Perrin
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 11, Pp 2354-2364 (2024)
Spinal cord injury results in significant sensorimotor deficits, currently, there is no curative treatment for the symptoms induced by spinal cord injury. Basic and pre-clinical research on spinal cord injury relies on the development and characteriz
Externí odkaz:
https://doaj.org/article/d04baa912f034b63ae077ea0702274ac
Autor:
Yannick N Gerber, Florence E Perrin
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 487-488 (2024)
Externí odkaz:
https://doaj.org/article/c8c3353c92e940b0b9b40c961efe9b6c
Autor:
Cylia Rochat, Nathalie Bernard‐Marissal, Emma Källstig, Sylvain Pradervand, Florence E. Perrin, Patrick Aebischer, Cédric Raoul, Bernard L. Schneider
Publikováno v:
Glia
Glia, Wiley, 2022, ⟨10.1002/glia.24140⟩
Glia, 2022, ⟨10.1002/glia.24140⟩
Glia, Wiley, 2022, ⟨10.1002/glia.24140⟩
Glia, 2022, ⟨10.1002/glia.24140⟩
In amyotrophic lateral sclerosis (ALS) caused by SOD1 gene mutations, both cell-autonomous and noncell-autonomous mechanisms lead to the selective degeneration of motoneurons (MN). Here, we evaluate the therapeutic potential of gene therapy targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e1f9283d784fb6dcafc113711daf4f
https://doi.org/10.1002/glia.24140
https://doi.org/10.1002/glia.24140