Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Florence Doval"'
Publikováno v:
Biochemical and biophysical research communications, vol 528, iss 3
Biochem Biophys Res Commun
Biochem Biophys Res Commun
Cytoskeletal transport in cells is driven by enzymes whose activity shows sensitive, typically Arrhenius, dependence on temperature. Often, the duration and outcome of cargo transport is determined by the relative success of kinesin vs. dynein motors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c86b70f74f7e7168f67d4ed237604a1
https://escholarship.org/uc/item/5150g0bv
https://escholarship.org/uc/item/5150g0bv
Autor:
Abhimanyu Sharma, Manasa Gudheti, Matthew Bovyn, Florence Doval, Michael Vershinin, Jared Bergman, Steven P. Gross, Jun Allard
Publikováno v:
Proceedings of the National Academy of Sciences. 115:537-542
The eukaryotic cell's microtubule cytoskeleton is a complex 3D filament network. Microtubules cross at a wide variety of separation distances and angles. Prior studies in vivo and in vitro suggest that cargo transport is affected by intersection geom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0790bfa5dd8e6c08559c481455d8d0a
https://doi.org/10.1073/pnas.1707936115
https://doi.org/10.1073/pnas.1707936115
Publikováno v:
Biochemical and Biophysical Research Communications. 493:1318-1321
Kinesin-1 is a mechanochemical enzyme which mediates long distance intracellular cargo transport along microtubules in a wide variety of eukaryotic cells. Kinesin is also relatively easy to purify and shows robust function in vitro, leading to numero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720ae1ac69651040bec095181aa93e60
https://doi.org/10.1016/j.bbrc.2017.09.172
https://doi.org/10.1016/j.bbrc.2017.09.172
Autor:
James P. Keener, Christopher E. Miles, Michael Vershinin, Olaolu Osunbayo, Florence Doval, Babu J.N. Reddy
Publikováno v:
Soft matter. 15(8)
We report a minimal microtubule-based motile system displaying signatures of unconventional diffusion. The system consists of a single model cargo driven by an ensemble of N340K NCD motors along a single microtubule. Despite the absence of cytosolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ff3ec677b66891ea1a5b02298d30b3
https://pubmed.ncbi.nlm.nih.gov/30698601
https://pubmed.ncbi.nlm.nih.gov/30698601
Publikováno v:
SPIE Proceedings.
Cytoskeletal networks are 3D arrangements of filaments whose complex spatial structure contributes significantly to their intracellular functions, e.g. biomechanics and cargo motility. Microtubule networks in cells are a particular challenge for in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0ce5f003d85656916605ef694db0f74
https://doi.org/10.1117/12.2237231
https://doi.org/10.1117/12.2237231
Publikováno v:
SPIE Newsroom.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13759b1d92e38a8d585d1d05275c5323
https://doi.org/10.1117/2.1201608.006690
https://doi.org/10.1117/2.1201608.006690
Autor:
Matthew Bovyn, Michael Vershinin, Florence Doval, Jun Allard, Manasa Gudheti, Jared Bergman, Steven P. Gross
Publikováno v:
Biophysical Journal. 114:656a
Author(s): Bovyn, Matthew Jacob | Advisor(s): Allard, Jun F; Gross, Steven P | Abstract: Eukaryotic cells transport cargos along microtubules to control their distribution within the cell and deliver them to distant locations. While we understand how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9d441f2688204c46688cf263015caa4
https://doi.org/10.1016/j.bpj.2017.11.3544
https://doi.org/10.1016/j.bpj.2017.11.3544