Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Florence De Smedt"'
Autor:
Steven Ramael, Florence De Smedt, Christian Otoul, Nathalie Toublanc, Armel Stockis, Pierre Boulanger, Jean-Michel Riethuisen
Publikováno v:
Clinical Therapeutics. 28:734-744
Background : Antiepileptic drugs are usually administere dorally, but alternative routes of drug delivery may be required when oral administration is not feasible. Objective : The purpose of this study was to evaluate the single-dose bioavailability
Autor:
Françoise Bex, Colette Moreau, Ludwig Missiaen, Christophe Erneux, Humbert De Smedt, Florence De Smedt, Frank Wuytack, Valérie Dewaste
Publikováno v:
Biochemical Journal. 374:41-49
Inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] 3-kinase catalyses the phosphorylation of InsP3 to inositol 1,3,4,5-tetrakisphosphate. cDNAs encoding three human isoenzymes of InsP3 3-kinase (A, B and C) have been reported previously [Choi, Kim, Lee, Moo
Autor:
Christophe Erneux, Jan B. Parys, Ludwig Missiaen, Valérie Vanweyenberg, Humbert De Smedt, Florence De Smedt
Publikováno v:
Journal of Biological Chemistry. 272:17367-17375
D-myo-Inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and 3-kinase are thought to be critical regulatory enzymes in the control of InsP3 and Ca2+ signaling. In brain and many other cells, type I InsP3 5-phosphatase is the major phosphatase that de
Publikováno v:
European Journal of Biochemistry. 234:598-602
The dephosphorylation of inositol 1,4,5-trisphosphate (InsP3) to inositol 1,4-bisphosphate is catalyzed by InsP3 5-phosphatase. The coding region of human brain type I InsP3 5-phosphatase was expressed as a fusion protein with the maltose-binding pro
Autor:
Daniel Blero, Christophe Erneux, Nathalie Paternotte, Bernard Payrastre, Colette Moreau, Florence De Smedt, Xavier Pesesse
Publikováno v:
Biochemical and biophysical research communications. 282(3)
The lipid phosphatase SHIP2 (SH2 domain containing inositol 5-phosphatase 2) has recently been shown to be a potent negative regulator of insulin signaling and insulin sensitivity in vivo. We show here that SHIP2 is expressed in Chinese hamster ovary
Publikováno v:
Biochemical and biophysical research communications. 239(3)
Distinct inositol and phosphatidylinositol polyphosphates 5-phosphatases have recently been cloned. Primers have been designed coding for highly conserved amino acid regions that are shared between sequences of 5-phosphatases. One of the PCR fragment
Autor:
Christophe Erneux, Peter J. Parker, A.Lyndsay Drayer, Florence De Smedt, Xavier Pesesse, Rüdiger Woscholski
Publikováno v:
Biochemical and biophysical research communications. 225(1)
Distinct inositol and phosphatidylinositol polyphosphate 5-phosphatases have recently been cloned. Primers were designated coding for highly conserved amino acid regions that are shared between sequences of 5-phosphatases. We used degenerate primers
Publikováno v:
Scopus-Elsevier
In brain, type I inositol-1,4,5-trisphosphate 5-phosphatase (InsP3 5-phosphatase) is the major isoenzyme hydrolyzing the calcium-mobilizing second messenger InsP3. Activity of this enzyme could be measured in both soluble and particulate fractions of
Autor:
Jean-Marie Vanderwinden, Christophe Erneux, Florence De Smedt, Koji Isozaki, Serge N. Schiffmann
Publikováno v:
Gastroenterology. 120:A493-A494
Publikováno v:
Biochemical Society Transactions. 24:623S-623S