Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Florence Coulet"'
Autor:
Vincent Jonchère, Hugo Montémont, Enora Le Scanf, Aurélie Siret, Quentin Letourneur, Emmanuel Tubacher, Christophe Battail, Assane Fall, Karim Labreche, Victor Renault, Toky Ratovomanana, Olivier Buhard, Ariane Jolly, Philippe Le Rouzic, Cody Feys, Emmanuelle Despras, Habib Zouali, Rémy Nicolle, Pascale Cervera, Magali Svrcek, Pierre Bourgoin, Hélène Blanché, Anne Boland, Jérémie Lefèvre, Yann Parc, Mehdi Touat, Franck Bielle, Danielle Arzur, Gwennina Cueff, Catherine Le Jossic-Corcos, Gaël Quéré, Gwendal Dujardin, Marc Blondel, Cédric Le Maréchal, Romain Cohen, Thierry André, Florence Coulet, Pierre de la Grange, Aurélien de Reyniès, Jean-François Fléjou, Florence Renaud, Agusti Alentorn, Laurent Corcos, Jean-François Deleuze, Ada Collura, Alex Duval
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Background Microsatellite instability (MSI) due to mismatch repair deficiency (dMMR) is common in colorectal cancer (CRC). These cancers are associated with somatic coding events, but the noncoding pathophysiological impact of this genomic i
Externí odkaz:
https://doaj.org/article/87efc7be65b6480c8bf4509103a6aab4
Autor:
Marine Baron, Karim Labreche, Marianne Veyri, Nathalie Désiré, Amira Bouzidi, Fatou Seck-Thiam, Frédéric Charlotte, Alice Rousseau, Véronique Morin, Cécilia Nakid-Cordero, Baptiste Abbar, Alberto Picca, Marie Le Cann, Noureddine Balegroune, Nicolas Gauthier, Ioannis Theodorou, Mehdi Touat, Véronique Morel, Franck Bielle, Assia Samri, Agusti Alentorn, Marc Sanson, Damien Roos-Weil, Corinne Haioun, Elsa Poullot, Anne Langlois de Septenville, Frédéric Davi, Amélie Guihot, Pierre-Yves Boelle, Véronique Leblond, Florence Coulet, Jean-Philippe Spano, Sylvain Choquet, Brigitte Autran, IDeATIon study group
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Non-Hodgkin lymphomas (NHL) commonly occur in immune-deficient (ID) patients, both HIV-infected and transplanted, and are often EBV-driven with cerebral localization, raising the question of tumor immunogenicity, a critical issue for treatment respon
Externí odkaz:
https://doaj.org/article/4ed12c460a174df8aed7d61d4a12e426
Autor:
Hélène Théodon, Erell Guillerm, Johanna Wassermann, Gabrielle Deniziaut, Loïc Jaffrelot, Jérome Denis, Nathalie Chereau, Claude Bigorgne, Wiame Potonnier, Florence Coulet, Laurence Leenhardt, Camille Buffet
Publikováno v:
European Thyroid Journal, Vol 13, Iss 1, Pp 1-8 (2024)
Objective: Tumor molecular genotyping plays a key role in improving the management of advanced thyroid cancers. Molecular tests are classically performed on formalin-fixed, paraffin-embedded (FFPE) carcinoma tissue. However alternative molecular test
Externí odkaz:
https://doaj.org/article/f5d94238fced4a56a2db273d53397eaa
Autor:
Lionel Michaux, Alexandre Perrier, Camille Mehlman, Hussa Alshehhi, Antonin Dubois, Roger Lacave, Florence Coulet, Jacques Cadranel, Vincent Fallet
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionALK tyrosine kinase inhibitors (ALK TKIs) have improved prognosis in ALK-rearranged (ALK+) non-small-cell lung cancer (NSCLC). However, drug resistance mechanisms occur inevitably during the course of treatment leading to disease progress
Externí odkaz:
https://doaj.org/article/06fd295534f1460995506172ad4190f9
Autor:
Patrick R. Benusiglio, Vincent Fallet, Mateo Sanchis-Borja, Florence Coulet, Jacques Cadranel
Publikováno v:
European Respiratory Review, Vol 30, Iss 162 (2021)
Pathogenic genetic variants (formerly called mutations) present in the germline of some individuals are associated with a clinically relevant increased risk of developing lung cancer. These germline pathogenic variants are hereditary and are transmit
Externí odkaz:
https://doaj.org/article/c1b796d5fa504d2f9f941e325420e88a
Autor:
Amira Bouzidi, Karim Labreche, Marine Baron, Marianne Veyri, Jérôme Alexandre Denis, Mehdi Touat, Marc Sanson, Frédéric Davi, Erell Guillerm, Stéphanie Jouannet, Frédéric Charlotte, Franck Bielle, Sylvain Choquet, Pierre-Yves Boëlle, Jacques Cadranel, Véronique Leblond, Brigitte Autran, Jean-Marc Lacorte, Jean-Philippe Spano, Florence Coulet, the IDEATION study group, Ahmed Idbaih, Noureddine Balegroune, Amélie Guihot, Ioannis Theodorou, Agusti Alentorn, Isabelle Brocheriou, Anne-Geneviève, Damien Roos Weil, Alberto Picca
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cell-free DNA (cfDNA) analysis is a minimally invasive method that can be used to detect genomic abnormalities by directly testing a blood sample. This method is particularly useful for immunosuppressed patients, who are at high risk of complications
Externí odkaz:
https://doaj.org/article/d60de3ac6cae402cb2bbc555becfa333
Autor:
Agnieszka D'Antonio-Chronowska, Margaret K.R. Donovan, William W. Young Greenwald, Jennifer Phuong Nguyen, Kyohei Fujita, Sherin Hashem, Hiroko Matsui, Francesca Soncin, Mana Parast, Michelle C. Ward, Florence Coulet, Erin N. Smith, Eric Adler, Matteo D'Antonio, Kelly A. Frazer
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 924-938 (2019)
Summary: Despite the importance of understanding how variability across induced pluripotent stem cell (iPSC) lines due to non-genetic factors (clone and passage) influences their differentiation outcome, large-scale studies capable of addressing this
Externí odkaz:
https://doaj.org/article/8f78689b27d04687908913946f7fa60e
Autor:
Vincent Jonchere, Laetitia Marisa, Malorie Greene, Alain Virouleau, Olivier Buhard, Romane Bertrand, Magali Svrcek, Pascale Cervera, Anastasia Goloudina, Erell Guillerm, Florence Coulet, Samuel Landman, Toky Ratovomanana, Sylvie Job, Mira Ayadi, Nabila Elarouci, Lucile Armenoult, Fatiha Merabtene, Sylvie Dumont, Yann Parc, Jérémie H. Lefèvre, Thierry André, Jean-François Fléjou, Agathe Guilloux, Ada Collura, Aurélien de Reyniès, Alex Duval
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 3, Pp 277-300 (2018)
Background & Aims: Recent studies have shown that cancers arise as a result of the positive selection of driver somatic events in tumor DNA, with negative selection playing only a minor role, if any. However, these investigations were concerned with
Externí odkaz:
https://doaj.org/article/db668905d34649de97e087d79ac84a22
Autor:
Léo Mas, Renato M. Lupinacci, Jérôme Cros, Jean-Baptiste Bachet, Florence Coulet, Magali Svrcek
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6756 (2021)
Intraductal papillary mucinous neoplasms (IPMN) are common and one of the main precursor lesions of pancreatic ductal adenocarcinoma (PDAC). PDAC derived from an IPMN is called intraductal papillary mucinous carcinoma (IPMC) and defines a subgroup of
Externí odkaz:
https://doaj.org/article/b8d2975a2c194ab78e16b9aaf0395e68
Autor:
Matteo D′Antonio, Donate Weghorn, Agnieszka D′Antonio-Chronowska, Florence Coulet, Katrina M. Olson, Christopher DeBoever, Frauke Drees, Angelo Arias, Hakan Alakus, Andrea L. Richardson, Richard B. Schwab, Emma K. Farley, Shamil R. Sunyaev, Kelly A Frazer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Cancer driver mutations can occur within noncoding genomic sequences. Here, the authors develop a statistical approach to identify candidate noncoding driver mutations in DNase I hypersensitive sites in breast cancer and experimentally demonstrate th
Externí odkaz:
https://doaj.org/article/fed8c71471284e789fe9fe3936d957c5