Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Florence Baudin"'
Autor:
Benoît Arragain, Quentin Durieux Trouilleton, Florence Baudin, Jan Provaznik, Nayara Azevedo, Stephen Cusack, Guy Schoehn, Hélène Malet
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
La Crosse is a human life threatening virus belonging to the Bunyavirales order. The structure of its polymerase solved in seven key active states by cryo-electron microscopy reveals the molecular mechanisms of viral RNA replication and transcription
Externí odkaz:
https://doaj.org/article/baf0b7f62a9c4fc8a3d6e52a3256d0b6
Autor:
Ada Roy, Emeric Chan Mine, Lorenzo Gaifas, Cédric Leyrat, Valentina A. Volchkova, Florence Baudin, Luis Martinez-Gil, Viktor E. Volchkov, David G. Karlin, Jean-Marie Bourhis, Marc Jamin
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 455 (2023)
The protein C is a small viral protein encoded in an overlapping frame of the P gene in the subfamily Orthoparamyxovirinae. This protein, expressed by alternative translation initiation, is a virulence factor that regulates viral transcription, repli
Externí odkaz:
https://doaj.org/article/6b1b455b2d7547619ee63737e9669b89
Autor:
Matthias K. Vorländer, Anna Jungblut, Kai Karius, Florence Baudin, Helga Grötsch, Jan Kosinski, Christoph W. Müller
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Transcription factor TFIIIC plays roles in Pol III transcription and in chromatin organization. CryoEM structure of the yeast TFIIIC subcomplex τA, a negative stain reconstruction of τA bound to the TFIIIB subunits Brf1 and TBP and accompanying bio
Externí odkaz:
https://doaj.org/article/0338fb67478441cfbefda6b1f35f56f9
Autor:
Yashar Sadian, Florence Baudin, Lucas Tafur, Brice Murciano, Rene Wetzel, Felix Weis, Christoph W. Müller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
RNA polymerase I (Pol I) catalyses the transcription of pre-ribosomal RNA and for transcription initiation Pol I assembles with core factor and Rrn3 on the rDNA core promoter. Here the authors provide insights into the molecular mechanism of promoter
Externí odkaz:
https://doaj.org/article/2f9e5295c8a243efb432a2a00bad71af
Autor:
Sylvie Chenavas, Leandro F Estrozi, Anny Slama-Schwok, Bernard Delmas, Carmelo Di Primo, Florence Baudin, Xinping Li, Thibaut Crépin, Rob W H Ruigrok
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003275 (2013)
Isolated influenza A virus nucleoprotein exists in an equilibrium between monomers and trimers. Samples containing only monomers or only trimers can be stabilized by respectively low and high salt. The trimers bind RNA with high affinity but remain t
Externí odkaz:
https://doaj.org/article/767b2dcbd0d8491dabdd8d98b1ca485c
Autor:
Christoph W. Müller, Wim J. H. Hagen, Rene Wetzel, Robyn D. Moir, Matthias K. Vorländer, Florence Baudin, Ian M. Willis
Publikováno v:
Nature structural & molecular biology
Maf1 is a conserved inhibitor of RNA polymerase III (Pol III) that influences phenotypes ranging from metabolic efficiency to lifespan. Here, we present a 3.3-A-resolution cryo-EM structure of yeast Maf1 bound to Pol III, establishing that Maf1 seque
Autor:
Florence Baudin, Brice Murciano, Christoph Müller, Simon A Fromm, Simone Mattei, Julia Mahamid, Herman KH Fung
SummaryPre-ribosomal RNA is selectively transcribed by RNA Polymerase (Pol) I in eukaryotes. The yeast transcription factor Upstream Activating Factor (UAF) represses Pol II transcription and mediates Pol I preinitiation complex (PIC) formation durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9385a0e50d3a388f2984e3ab6b6e08
https://doi.org/10.1101/2022.02.10.479882
https://doi.org/10.1101/2022.02.10.479882
Autor:
Magdalena Büscher, Rastislav Horos, Ina Huppertz, Kevin Haubrich, Nikolay Dobrev, Florence Baudin, Janosch Hennig, Matthias W. Hentze
Publikováno v:
RNA
Cellular processes can be regulated at multiple levels, including transcriptional, post-transcriptional, and post-translational mechanisms. We have recently shown that the small, noncoding vault RNA1–1 negatively riboregulates p62 oligomerization i
Autor:
Benoît Arragain, Quentin Durieux Trouilleton, Florence Baudin, Jan Provaznik, Nayara Azevedo, Stephen Cusack, Guy Schoehn, Hélène Malet
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.902. ⟨10.1038/s41467-022-28428-z⟩
Nature Communications, 2022, 13 (1), pp.902. ⟨10.1038/s41467-022-28428-z⟩
Segmented negative-strand RNA bunyaviruses encode a multi-functional polymerase that performs genome replication and transcription. Here, we establish conditions for in vitro activity of La Crosse virus polymerase and visualize its conformational dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b438e563a5d7aaea928db9dd1675e661
https://hal.univ-grenoble-alpes.fr/hal-03641463/file/arr1.pdf
https://hal.univ-grenoble-alpes.fr/hal-03641463/file/arr1.pdf
Autor:
Brice Murciano, Lucas Tafur, Yashar Sadian, Christoph W. Müller, Florence Baudin, Felix Weis, Rene Wetzel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
RNA polymerase I (Pol I) assembles with core factor (CF) and Rrn3 on the rDNA core promoter for transcription initiation. Here, we report cryo-EM structures of closed, intermediate and open Pol I initiation complexes from 2.7 to 3.7 Å resolution to