Physico-Chemical Characteristics and Posterolateral Fusion Performance of Biphasic Calcium Phosphate with Submicron Needle-Shaped Surface Topography Combined with a Novel Polymer Binder

Autor: Ruggero Belluomo, Inazio Arriola-Alvarez, Nathan W. Kucko, William R. Walsh, Joost D. de Bruijn, Rema A. Oliver, Dan Wills, James Crowley, Tian Wang, Florence Barrère-de Groot

Publikováno v: Materials; Volume 15; Issue 4; Pages: 1346

A biphasic calcium phosphate with submicron needle-shaped surface topography combined with a novel polyethylene glycol/polylactic acid triblock copolymer binder (BCP-EP) was investigated in this study. This study aims to evaluate the composition, deg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c995f39363f73c1cc19d97b111fe4516
https://doi.org/10.3390/ma15041346

Efficacy of a synthetic calcium phosphate with submicron surface topography as autograft extender in lapine posterolateral spinal fusion

Autor: Joost D. de Bruijn, Davide Barbieri, Huipin Yuan, Lukas A. van Dijk, Rema A. Oliver, Florence Barrère-de Groot, Chris Christou, William R. Walsh

Publikováno v: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Journal of Biomedical Materials Research Part B-applied Biomaterials, 107(6), 2080-2090. Wiley

Posterolateral spinal fusion (PLF) is a common procedure in orthopedic surgery that is performed to fuse adjacent vertebrae to reduce symptoms related to spinal conditions. In the current study, a novel synthetic calcium phosphate with submicron surf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385e4fb9d7953678ab3afe52188ae892
https://pubmed.ncbi.nlm.nih.gov/30614621

Osteoclast resorption of beta-tricalcium phosphate controlled by surface architecture

Autor: Bas ten Harkel, Florence Barrère-de Groot, Vincent Everts, Joost D. de Bruijn, Noel Davison, Xiaoman Luo, Ton Schoenmaker, Huipin Yuan

Publikováno v: Biomaterials, 35(26), 7441-7451. Elsevier BV
Biomaterials, 35(26), 7441-7451. Elsevier
Davison, N L, ten Harkel, B, Schoenmaker, T, Luo, X, Yuan, H, Everts, V, de Barrère-Groot, F & de Bruijn, J D 2014, ' Osteoclast resorption of beta-tricalcium phosphate controlled by surface architecture ', Biomaterials, vol. 35, no. 26, pp. 7441-7451 . https://doi.org/10.1016/j.biomaterials.2014.05.048

A resorbable bone graft substitute should mimic native bone in its capacity to support bone formation and be remodeled by osteoclasts (OCl) or other multinucleated cells such as foreign body giant cells (FBGC). We hypothesize that by changing the sca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c661cddc4b513c3f84217fccafa7ac0
https://hdl.handle.net/11245/1.431079

Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells

Autor: Huipin Yuan, Ana M.C. Barradas, Clemens van Blitterswijk, Zeinab Tahmasebi Birgani, Pamela Habibovic, Jan de Boer, Marcel J. T. Reinders, Veronica Monticone, Hugo Fernandes, Florence Barrère-de Groot, Charlene Danoux, Marc Hulsman

Publikováno v: Integrative Biology, 5(7), 920-931. Oxford University Press
Integrative biology, 5(7), 920-931. Royal Society of Chemistry

Calcium phosphate (CaP) based ceramics are used as bone graft substitutes in the treatment of bone defects. The physico-chemical properties of these materials determine their bioactivity, meaning that molecular and cellular responses in the body will

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeec8c13fb53505d59ba060a61dbb36a
https://doi.org/10.1039/c3ib40027a

Plug and play: combining materials and technologies to improve bone regenerative strategies

Autor: Lorenzo, Moroni, Anandkumar, Nandakumar, Florence Barrère-, de Groot, Clemens A, van Blitterswijk, Pamela, Habibovic

Publikováno v: Journal of tissue engineering and regenerative medicine. 9(7)

Despite recent advances in the development of biomaterials intended to replace natural bone grafts for the regeneration of large, clinically relevant defects, most synthetic solutions that are currently applied in the clinic are still inferior to nat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::779eb805604b6aabd1fbf8a37f0208f3
https://pubmed.ncbi.nlm.nih.gov/23671062