Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Flore Gouel"'
Autor:
Bruce Do Van, Flore Gouel, Aurélie Jonneaux, Kelly Timmerman, Patrick Gelé, Maud Pétrault, Michèle Bastide, Charlotte Laloux, Caroline Moreau, Régis Bordet, David Devos, Jean-Christophe Devedjian
Publikováno v:
Neurobiology of Disease, Vol 94, Iss , Pp 169-178 (2016)
Parkinson's disease (PD) is a complex illness characterized by progressive dopaminergic neuronal loss. Several mechanisms associated with the iron-induced death of dopaminergic cells have been described. Ferroptosis is an iron-dependent, regulated ce
Externí odkaz:
https://doaj.org/article/a4e830d890a547978748184ac311bb5c
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that typically results in death within 3–5 years after diagnosis. To date, there is no curative treatment and therefore an urgent unmet need of neuroprotective and/or neurores
Externí odkaz:
https://doaj.org/article/315ab431f7f8454d821621d82fbcc187
Autor:
Flore Gouel, Kelly Timmerman, Philippe Gosset, Cedric Raoul, Mary Dutheil, Aurélie Jonneaux, Guillaume Garçon, Caroline Moreau, Veronique Danel-Brunaud, James Duce, Thierry Burnouf, Jean-Christophe Devedjian, David Devos
Publikováno v:
Biomaterials
Biomaterials, 2021, 280, pp.121311. ⟨10.1016/j.biomaterials.2021.121311⟩
Biomaterials, 2021, 280, pp.121311. ⟨10.1016/j.biomaterials.2021.121311⟩
International audience; Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease of motor neurons leading to death within 3 years and without a curative treatment. Neurotrophic growth factors (NTFs) are pivotal for cell survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b1f828775ff9c18933d3c7ad3c1b53
https://hal.univ-lille.fr/hal-03646887
https://hal.univ-lille.fr/hal-03646887
Autor:
James A. Duce, Veronique Danel, Anne-Sophie Rolland, Flore Gouel, Hind Bouchaoui, Caroline Moreau, Z. Ioav Cabantchik, Laura Mahoney-Sanchez, Jean-Christophe Devedjian, David Devos
Publikováno v:
Journal of Neural Transmission
Journal of Neural Transmission, Springer Verlag, 2020, 127 (2), pp.189-203. ⟨10.1007/s00702-019-02138-1⟩
Journal of Neural Transmission, 2020, 127 (2), pp.189-203. ⟨10.1007/s00702-019-02138-1⟩
Journal of Neural Transmission, Springer Verlag, 2020, 127 (2), pp.189-203. ⟨10.1007/s00702-019-02138-1⟩
Journal of Neural Transmission, 2020, 127 (2), pp.189-203. ⟨10.1007/s00702-019-02138-1⟩
Focal iron accumulation associated with brain iron dyshomeostasis is a pathological hallmark of various neurodegenerative diseases (NDD). The application of iron-sensitive sequences in magnetic resonance imaging has provided a useful tool to identify
Autor:
Charlotte Veyrat-Durebex, Renaud Lopes, Maeva Kyheng, Guillaume Grolez, Guillaume Garçon, Florent Auger, Luc Defebvre, Thierry Perez, Flore Gouel, Veronique Danel, Kelly Timmerman, James A. Duce, Jean-Christophe Devedjian, Mary Dutheil, Pierre-François Pradat, Philippe Corcia, Luc Dupuis, Grégory Kuchcinski, Caroline Moreau, Ioav Cabantchik, Markus Otto, Maud Pétrault, David Devos, Régis Bordet, Alain Duhamel, Charlotte Laloux, Aurélie Jonneaux, Patrick Oeckl, Cédrick Lachaud, Hélène Blasco
Publikováno v:
Antioxidants & Redox Signaling. 29:742-748
Iron accumulation has been observed in mouse models and in both sporadic and familial forms of amyotrophic lateral sclerosis (ALS). Iron chelation could reduce iron accumulation and the related excess of oxidative stress in the motor pathways. Howeve
Autor:
Hung-Ming Chang, Kelly Timmerman, Jean-Christophe Devedjian, Ting-Yi Renn, Liang Tzung Lin, David Devos, Ming-Li Chou, Charlotte Laloux, Aurélie Jonneaux, Thierry Burnouf, Flore Gouel, Joe-Wei Wu
Publikováno v:
Biomaterials. 142:77-89
Human platelet lysates (PLs), which contain multiple neurotrophins , have been proposed for treating neurodegenerative disorders, including Parkinson's disease (PD). However, current PLs suspended in plasma have high protein content and contain fibri
Autor:
Caroline Moreau, Ming Li Chou, David Devos, Régis Bordet, Flore Gouel, Bruce Do Van, Jean Christophe Devedjian, Thierry Burnouf, Aurélie Jonneaux
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11:3236-3240
Neurodegenerative diseases have huge economic and societal impacts, and place an immense emotional burden on patients and caregivers. Given that platelets have an essential physiological role in wound healing and tissue repair, human platelet lysates
Autor:
Flore Gouel, Michèle Bastide, Patrick Gelé, Régis Bordet, Kelly Timmerman, Jean-Christophe Devedjian, Caroline Moreau, Aurélie Jonneaux, Charlotte Laloux, Maud Pétrault, David Devos, Bruce Do Van
Publikováno v:
Neurobiology of Disease, Vol 94, Iss, Pp 169-178 (2016)
Parkinson's disease (PD) is a complex illness characterized by progressive dopaminergic neuronal loss. Several mechanisms associated with the iron-induced death of dopaminergic cells have been described. Ferroptosis is an iron-dependent, regulated ce
Autor:
David Devos, Caroline Moreau, Maud Pétrault, Flore Gouel, Charlotte Laloux, Cédrick Lachaud, Guillaume Garçon, James A. Duce, Nathalie Rouaix, Kelly Timmerman, Jean-Christophe Devedjian, B. Do Van, Régis Bordet, Aurélie Jonneaux
Publikováno v:
Neurobiology of Disease
Neurobiology of Disease, 2017, ⟨10.1016/j.nbd.2017.03.013⟩
Neurobiology of Disease, Elsevier, 2017, ⟨10.1016/j.nbd.2017.03.013⟩
Neurobiology of Disease, Vol 103, Iss, Pp 24-31 (2017)
Neurobiology of Disease, 2017, ⟨10.1016/j.nbd.2017.03.013⟩
Neurobiology of Disease, Elsevier, 2017, ⟨10.1016/j.nbd.2017.03.013⟩
Neurobiology of Disease, Vol 103, Iss, Pp 24-31 (2017)
International audience; In Parkinson’s disease (PD) depletion of dopamine in the nigro-striatal pathway is a main pathological hallmark that requires continuous and focal restoration. Current predominant treatment with intermittent oral administrat
Publikováno v:
BMC Cancer
BMC Cancer, BioMed Central, 2016, 16, pp.746. ⟨10.1186/s12885-016-2776-1⟩
BMC Cancer, BioMed Central, 2016, 16, pp.746. ⟨10.1186/s12885-016-2776-1⟩
Background Several studies show that bone marrow (BM) microenvironment and hypoxia condition can promote the survival of leukemic cells and induce resistance to anti-leukemic drugs. However, the molecular mechanism for chemoresistance by hypoxia is n