Use of activity-based probes to develop high throughput screening assays that can be performed in complex cell extracts.

Autor: Edgar Deu, Zhimou Yang, Flora Wang, Michael Klemba, Matthew Bogyo

Publikováno v: PLoS ONE, Vol 5, Iss 8, p e11985 (2010)

High throughput screening (HTS) is one of the primary tools used to identify novel enzyme inhibitors. However, its applicability is generally restricted to targets that can either be expressed recombinantly or purified in large quantities.Here, we de

Externí odkaz: https://doaj.org/article/0ce1df1976f14de189a947acc629f15c

Knowledge of Sugars Consumption and the WHO Sugars Guideline among Canadian Dietitians and Other Health Professionals

Autor: Flora Wang, Nick Bellissimo, Laura Pasut, David D. Kitts, Sandra L. Marsden, Chiara DiAngelo

Publikováno v: Canadian Journal of Dietetic Practice and Research. 81:142-145

Purpose: The objective was to assess knowledge related to sugars consumption and World Health Organization (WHO) sugars guideline among Canadian dietitians and other health professionals. Methods: A multiple-choice style survey was administered at Di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d547a921d8d4f707a21709376956f95
https://doi.org/10.3148/cjdpr-2020-004

Measuring the predictability of life outcomes with a scientific mass collaboration

Autor: Kristin E. Porter, Malte Möser, Flora Wang, Bingyu Zhao, Wei Lee Woon, Yoshihiko Suhara, Adaner Usmani, Erik H. Wang, Kun Jin, Samantha Weissman, William Eggert, Hamidreza Omidvar, Andrew Or, Lisa M Hummel, Gregory Faletto, Ben Sender, Qiankun Niu, Viola Mocz, Antje Kirchner, Catherine Wu, Karen Ouyang, Ian Lundberg, Allison C. Morgan, Abdulla Alhajri, Arvind Narayanan, Khaled AlGhoneim, Louis Raes, Ilana M. Horwitz, Barbara E. Engelhardt, Ben Leizman, Crystal Qian, Drew Altschul, Guanhua He, Jeanne Brooks-Gunn, Ridhi Kashyap, Eaman Jahani, Ryan James Compton, Anna Filippova, Sara McLanahan, Tejomay Gadgil, Claudia V. Roberts, Muna Adem, Julia Wang, Jeremy Freese, Alexander T. Kindel, Daniel E Rigobon, Naijia Liu, Lisa P. Argyle, Mayank Mahajan, Jonathan D Tang, Moritz Hardt, Ethan Porter, Diana Mercado-Garcia, Andrew Halpern-Manners, Anahit Sargsyan, Duncan J. Watts, Alex Pentland, Sonia P Hashim, Dean Knox, Onur Varol, Ryan Amos, James M. Wu, Thomas Davidson, Emma Tsurkov, Bernie Hogan, Areg Karapetyan, William Nowak, Jingwen Yin, Livia Baer-Bositis, Landon Schnabel, Chenyun Zhu, Noah Mandell, Ahmed Musse, Yue Gao, Josh Gagné, Stephen McKay, Jennie E. Brand, Abdullah Almaatouq, Katy M. Pinto, Andrew E Mack, Austin van Loon, Bedoor K. AlShebli, Helge Marahrens, Xiafei Wang, Bryan Schonfeld, Sonia Hausen, Kengran Yang, Maria Wolters, Brandon M. Stewart, Naman Jain, Moritz Büchi, Nicole Bohme Carnegie, Redwane Amin, Caitlin Ahearn, Kirstie Whitaker, Bo-Ryehn Chung, Diana Stanescu, Thomas Schaffner, Patrick Kaminski, David Jurgens, Kivan Polimis, Kimberly Higuera, Zhilin Fan, Matthew J. Salganik, Debanjan Datta, Connor Gilroy, E H Kim, Katariina Mueller-Gastell, Karen Levy, Brian J. Goode, Zhi Wang, Tamkinat Rauf

Publikováno v: PNAS
Proceedings of the National Academy of Sciences of the United States of America (PNAS), 117(15), 8398-8403. NATL ACAD SCIENCES
Proc Natl Acad Sci U S A
Salganik, M J, Lundberg, I, Kindel, A T, Ahearn, C E, Al-ghoneim, K, Almaatouq, A, Altschul, D M, Brand, J E, Carnegie, N B, Compton, R J, Datta, D, Davidson, T, Filippova, A, Gilroy, C, Goode, B J, Jahani, E, Kashyap, R, Kirchner, A, Mckay, S, Morgan, A C, Pentland, A, Polimis, K, Raes, L, Rigobon, D E, Roberts, C V, Stanescu, D M, Suhara, Y, Usmani, A, Wang, E H, Adem, M, Alhajri, A, Alshebli, B, Amin, R, Amos, R B, Argyle, L P, Baer-bositis, L, Büchi, M, Chung, B, Eggert, W, Faletto, G, Fan, Z, Freese, J, Gadgil, T, Gagné, J, Gao, Y, Halpern-manners, A, Hashim, S P, Hausen, S, He, G, Higuera, K, Hogan, B, Horwitz, I M, Hummel, L M, Jain, N, Jin, K, Jurgens, D, Kaminski, P, Karapetyan, A, Kim, E H, Leizman, B, Liu, N, Möser, M, Mack, A E, Mahajan, M, Mandell, N, Marahrens, H, Mercado-garcia, D, Mocz, V, Mueller-gastell, K, Musse, A, Niu, Q, Nowak, W, Omidvar, H, Or, A, Ouyang, K, Pinto, K M, Porter, E, Porter, K E, Qian, C, Rauf, T, Sargsyan, A, Schaffner, T, Schnabel, L, Schonfeld, B, Sender, B, Tang, J D, Tsurkov, E, Van Loon, A, Varol, O, Wang, X, Wang, Z, Wang, J, Wang, F, Weissman, S, Whitaker, K, Wolters, M K, Woon, W L, Wu, J, Wu, C, Yang, K, Yin, J, Zhao, B, Zhu, C, Brooks-gunn, J, Engelhardt, B E, Hardt, M, Knox, D, Levy, K, Narayanan, A, Stewart, B M, Watts, D J & Mclanahan, S 2020, ' Measuring the predictability of life outcomes with a scientific mass collaboration ', Proceedings of the National Academy of Sciences, vol. 117, no. 15, pp. 8398-8403 . https://doi.org/10.1073/pnas.1915006117

© This open access article is distributed under Creative Commons Attribution-NonCommercialNoDerivatives License 4.0 (CC BY-NC-ND). How predictable are life trajectories? We investigated this question with a scientific mass collaboration using the co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e79e5a0edeb2b5d23585b10ea4b178d
https://doi.org/10.1073/pnas.1915006117

Canadian Adults with Moderate Intakes of Total Sugars have Greater Intakes of Fibre and Key Micronutrients: Results from the Canadian Community Health Survey 2015 Public Use Microdata File

Autor: Ye Flora Wang, Sandra L. Marsden, Kaitlin Roke, John L. Sievenpiper, Chiara DiAngelo, Laura Chiavaroli

Publikováno v: Nutrients, Vol 12, Iss 1124, p 1124 (2020)
Nutrients
Volume 12
Issue 4

Background: Global dietary guidelines recommend reducing free sugars intake, which may affect choices of sugars-containing foods, including important sources of key micronutrients. The purpose of the study was to compare the intakes of nutrients stra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd30b78046eb1f2fbf82ffaa08de0829
https://www.mdpi.com/2072-6643/12/4/1124

ADrosophilaLexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research

Autor: Deanna Havey, Uriel Tayvah, Lydia Stahr, Anika Ayyar, Theresa Clark, Grace E Kim, Lutz Kockel, Townley Chisholm, Ja-Hon Wang, Samuel Han, Diane Lee, Dana Tung, Anne E. Rankin, Jiapei Chen, Eun Soo Jackie Kim, Christina Savvides, Seung K. Kim, Elle MacAlpine, Sarah Xiao, Kaelina Lombardo, Madeline Logan, Sangbin Park, Hansen Shi, Sydni M. Topper, Ida Piyale, Emma Herold, Vahid Fazel-Rezai, Flora Wang, Lutfi Huq, Ravi Jagadeesan, Cheryl Rotondo, Trang Duong

Publikováno v: G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 6, Iss 10, Pp 3017-3026 (2016)

Novel binary gene expression tools like the LexA-LexAop system could powerfully enhance studies of metabolism, development, and neurobiology in Drosophila. However, specific LexA drivers for neuroendocrine cells and many other developmentally relevan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b1a5ca7055aa41a35655ad46f3ea06
https://doi.org/10.1534/g3.116.031229