Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Flora Moreau"'
Autor:
Andrea Michela Biolato, Liza Filali, Diogo Pereira Fernandes, Flora Moreau, Takouhie Mgrditchian, Céline Hoffmann, Clément Thomas
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The formation of a lytic immunological synapse (IS) is crucial for cytotoxic lymphocytes to accurately target and effectively eliminate malignant cells. While significant attention has been focused on the lymphocyte side of the IS, particularly its r
Externí odkaz:
https://doaj.org/article/40bc63f8a2e14f1180086ed51cbcecb9
Autor:
Takouhie Mgrditchian, Joshua Brown-Clay, Céline Hoffmann, Tanja Müller, Liza Filali, Elena Ockfen, Xianqing Mao, Flora Moreau, Carla Pou Casellas, Tony Kaoma, Michel Mittelbronn, Clément Thomas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The actin cytoskeleton plays a critical role in cancer cell invasion and metastasis; however, the coordination of its multiple functions remains unclear. Actin dynamics in the cytoplasm control the formation of invadopodia, which are membrane protrus
Externí odkaz:
https://doaj.org/article/c2b8619594984cbea893d4b0fc76ae51
Autor:
Céline Hoffmann, Xianqing Mao, Joshua Brown-Clay, Flora Moreau, Antoun Al Absi, Hannah Wurzer, Barbara Sousa, Fernando Schmitt, Guy Berchem, Bassam Janji, Clément Thomas
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Hypoxia is a common feature of solid tumours that promotes invasion and metastatic dissemination. Invadopodia are actin-rich membrane protrusions that direct extracellular matrix proteolysis and facilitate tumour cell invasion. Here, we show
Externí odkaz:
https://doaj.org/article/9aa369442f8843179906f34893c25651
Autor:
Clément Thomas, Bassam Janji, Guy Berchem, Salem Chouaib, Jean-Paul Thiery, Monika Dieterle, Carla Pou Casellas, Rémi Petrolli, Joshua Brown-Clay, Xianqing Mao, Flora Moreau, Celine Hoffmann, Coralie Guerin, Hannah Wurzer, Antoun Al Absi
Time lapse imaging movie showing typical actin cytoskeleton configurations and dynamics in MCF-7 cells upon NK cell attack. Individual Z stacks were taken every minute over a period of 77 minutes. Time lapse movies were assembled from the Z stacks in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af14936bf2a012f94ccb69d0a5209b7
https://doi.org/10.1158/0008-5472.22419207
https://doi.org/10.1158/0008-5472.22419207
Autor:
Clément Thomas, Bassam Janji, Guy Berchem, Salem Chouaib, Jean-Paul Thiery, Monika Dieterle, Carla Pou Casellas, Rémi Petrolli, Joshua Brown-Clay, Xianqing Mao, Flora Moreau, Celine Hoffmann, Coralie Guerin, Hannah Wurzer, Antoun Al Absi
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894299a75f7b6b6237c1ec33090038e3
https://doi.org/10.1158/0008-5472.22419222.v1
https://doi.org/10.1158/0008-5472.22419222.v1
Autor:
Clément Thomas, Bassam Janji, Guy Berchem, Salem Chouaib, Jean-Paul Thiery, Monika Dieterle, Carla Pou Casellas, Rémi Petrolli, Joshua Brown-Clay, Xianqing Mao, Flora Moreau, Celine Hoffmann, Coralie Guerin, Hannah Wurzer, Antoun Al Absi
Elucidation of the underlying molecular mechanisms of immune evasion in cancer is critical for the development of immunotherapies aimed to restore and stimulate effective antitumor immunity. Here, we evaluate the role of the actin cytoskeleton in bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e5ff98625536d267b667e7b1da51f9
https://doi.org/10.1158/0008-5472.c.6510318.v1
https://doi.org/10.1158/0008-5472.c.6510318.v1
Autor:
Clément Thomas, Bassam Janji, Guy Berchem, Salem Chouaib, Jean-Paul Thiery, Monika Dieterle, Carla Pou Casellas, Rémi Petrolli, Joshua Brown-Clay, Xianqing Mao, Flora Moreau, Celine Hoffmann, Coralie Guerin, Hannah Wurzer, Antoun Al Absi
Supplementary Figures S1-S6 and their legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048eb6dc9d96e562f0a177f68b1d5a19
https://doi.org/10.1158/0008-5472.22419225
https://doi.org/10.1158/0008-5472.22419225
Autor:
Céline Hoffmann, Xianqing Mao, Rémi Petrolli, Carla Pou Casellas, Antoun Al Absi, Clément Thomas, Flora Moreau, Monika Dieterle, Jean Paul Thiery, Guy Berchem, Hannah Wurzer, Salem Chouaib, Joshua D. Brown-Clay, Coralie L. Guerin, Bassam Janji
Publikováno v:
Cancer Research. 78:5631-5643
Elucidation of the underlying molecular mechanisms of immune evasion in cancer is critical for the development of immunotherapies aimed to restore and stimulate effective antitumor immunity. Here, we evaluate the role of the actin cytoskeleton in bre
Autor:
Céline Hoffman, Tony Kaoma, Guy Berchem, Vanessa Marani, Clément Thomas, Xianqing Mao, Carla Pou Casellas, Joshua D. Brown-Clay, Flora Moreau
Publikováno v:
SSRN Electronic Journal.
The actin cytoskeleton has multiple functions in cancer cell invasion and metastasis; yet how these functions are coordinated remains unclear. In the cytoplasm, actin is necessary for the formation of specialized membrane protrusions, termed invadopo
Autor:
Monika Dieterle, Xianqing Mao, Antoun Al Absi, Céline Hoffmann, Bassam Janji, Anais Oudin, Guy Berchem, Flora Moreau, André Steinmetz, Clément Thomas
Publikováno v:
Oncotarget
// Celine Hoffmann 1,* , Xianqing Mao 1,* , Monika Dieterle 1,2 , Flora Moreau 1 , Antoun Al Absi 1 , Andre Steinmetz 3 , Anais Oudin 2 , Guy Berchem 1 , Bassam Janji 1 and Clement Thomas 1 1 Laboratory of Experimental Cancer Research, Department of