Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Flora Magnotti"'
Autor:
Daria Chirita, Pauline Bronnec, Flora Magnotti, Sarah Dalmon, Amandine Martin, Michel Popoff, Mathieu Gerfaud-Valentin, Pascal Sève, Alexandre Belot, Anne Contis, Agnes Duquesne, Gaetane Nocturne, Irene Lemelle, Sophie Georgin-Lavialle, Guilaine Boursier, Isabelle Touitou, Yvan Jamilloux, Thomas Henry
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-13 (2023)
Abstract Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disorder. FMF is caused by mutations in the MEFV gene, encoding pyrin, an inflammasome sensor. The best characterized pathogenic mutations associated with FMF c
Externí odkaz:
https://doaj.org/article/841b7afa0a4946cea0db40b6d874a0f4
Autor:
Haleema S. Malik, Flora Magnotti, Nicole A. Loeven, Jose M. Delgado, Arminja N. Kettenbach, Thomas Henry, James B. Bliska
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Pyrin is a pattern-recognition receptor in phagocytes that triggers caspase-1 inflammasome assembly in response to bacterial toxins and effectors that inactivate RhoA. Pyrin contains oligomerization domains and is negatively regulated by pho
Externí odkaz:
https://doaj.org/article/2302a06269a34f1d8a4db0928e381e9a
Autor:
Flora Magnotti, Lucie Lefeuvre, Sarah Benezech, Tiphaine Malsot, Louis Waeckel, Amandine Martin, Sébastien Kerever, Daria Chirita, Marine Desjonqueres, Agnès Duquesne, Mathieu Gerfaud‐Valentin, Audrey Laurent, Pascal Sève, Michel‐Robert Popoff, Thierry Walzer, Alexandre Belot, Yvan Jamilloux, Thomas Henry
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 11, Pp n/a-n/a (2019)
Abstract Familial Mediterranean fever (FMF) is the most frequent hereditary systemic autoinflammatory syndrome. FMF is usually caused by biallelic mutations in the MEFV gene, encoding Pyrin. Conclusive genetic evidence lacks for about 30% of patients
Externí odkaz:
https://doaj.org/article/0f098d55568642c791bf46c448c8724b
Autor:
Brice Lagrange, Sacha Benaoudia, Pierre Wallet, Flora Magnotti, Angelina Provost, Fanny Michal, Amandine Martin, Flaviana Di Lorenzo, Bénédicte F. Py, Antonio Molinaro, Thomas Henry
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Lipid A from some bacteria is sensed differently by humans and mice for the activation of the inflammasomes and inflammatory responses, but the mechanisms are not clear. Here, the authors show that murine caspase-11 and human caspase-4/5 contribute t
Externí odkaz:
https://doaj.org/article/383b81a68c0640c08b987c32fdbd2fe2
Autor:
Orso Maria Lucherini, Laura Obici, Manuela Ferracin, Valerio Fulci, Michael F McDermott, Giampaolo Merlini, Isabella Muscari, Flora Magnotti, Laura J Dickie, Mauro Galeazzi, Massimo Negrini, Cosima Tatiana Baldari, Rolando Cimaz, Luca Cantarini
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73443 (2013)
Tumor necrosis factor-receptor associated periodic syndrome (TRAPS) is a rare autosomal dominant autoinflammatory disorder characterized by recurrent episodes of long-lasting fever and inflammation in different regions of the body, such as the muscul
Externí odkaz:
https://doaj.org/article/89394c9242c041b98065efd6ab4e099e
Autor:
Orso Maria Lucherini, Laura Obici, Manuela Ferracin, Valerio Fulci, Michael F. McDermott, Giampaolo Merlini, Isabella Muscari, Flora Magnotti, Laura J. Dickie, Mauro Galeazzi, Massimo Negrini, Cosima Tatiana Baldari, Rolando Cimaz, Luca Cantarini
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/e4751ff4fd6042ca9f3018192579642b
Autor:
Antonio Vitale, Donato Rigante, Orso Maria Lucherini, Francesco Caso, Isabella Muscari, Flora Magnotti, Maria Giuseppina Brizi, Susanna Guerrini, Maria Patti, Leonardo Punzi, Mauro Galeazzi, Luca Cantarini
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Treatment of monogenic autoinflammatory disorders, an expanding group of hereditary diseases characterized by apparently unprovoked recurrent episodes of inflammation, without high-titre autoantibodies or antigen-specific T cells, has been revolution
Externí odkaz:
https://doaj.org/article/06b43fea8a5c4944a4e41bf05b646e51
Autor:
Daria Chirita, Pauline Bronnec, Flora Magnotti, Sarah Dalmon, Amandine Martin, Michel Popoff, Mathieu Gerfaud-Valentin, Pascal Sève, Alexandre Belot, Anne Contis, Agnes Duquesne, Gaetane Nocturne, Irene Lemelle, Sophie Georgin-Lavialle, Guilaine Boursier, Isabelle Touitou, Yvan Jamilloux, Thomas Henry
Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disorder. FMF is caused by mutations in the MEFV gene, encoding pyrin, an inflammasome sensor. The best characterized pathogenic mutations associated with FMF cluster in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c417b8db8a7577a3589605b052e3ba
https://doi.org/10.21203/rs.3.rs-2214035/v1
https://doi.org/10.21203/rs.3.rs-2214035/v1
Autor:
Flora Magnotti, Daria Chirita, Sarah Dalmon, Amandine Martin, Pauline Bronnec, Jeremy Sousa, Olivier Helynck, Wonyong Lee, Daniel L. Kastner, Jae Jin Chae, Michael F. McDermott, Alexandre Belot, Michel Popoff, Pascal Sève, Sophie Georgin-Lavialle, Hélène Munier-Lehmann, Tu Anh Tran, Ellen De Langhe, Carine Wouters, Yvan Jamilloux, Thomas Henry
Publikováno v:
Cell Reports
Cell Reports, 2022, 41 (2), pp.111472. ⟨10.1016/j.celrep.2022.111472⟩
Cell Reports, 2022, Oct 11, 41
Cell Reports, 2022, 41 (2), pp.111472. ⟨10.1016/j.celrep.2022.111472⟩
Cell Reports, 2022, Oct 11, 41
The pyrin inflammasome acts as a guard of RhoA GTPases and is central to immune defenses against RhoA-manipulating pathogens. Pyrin activation proceeds in two steps. Yet, the second step is still poorly understood. Using cells constitutively activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc1fcf53e644d6862e6fc68a8c43bf7
https://hal.science/hal-03811426/file/mmc3(1).pdf
https://hal.science/hal-03811426/file/mmc3(1).pdf
Publikováno v:
Effector-Triggered Immunity
Effector-Triggered Immunity, 2523, Springer US, pp.179-195, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2449-4_12⟩
Methods in Molecular Biology ISBN: 9781071624487
Effector-Triggered Immunity, 2523, Springer US, pp.179-195, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2449-4_12⟩
Methods in Molecular Biology ISBN: 9781071624487
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5c013fb4e074a4196962cf7601d889
https://hal.science/hal-03790138
https://hal.science/hal-03790138