Zobrazeno 1 - 10
of 3 333
pro vyhledávání: '"Flora M."'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Little is known about the origin of germ cells in humans. We previously leveraged post-zygotic mutations to reconstruct zygote-rooted cell lineage ancestry trees in a phenotypically normal woman, termed NC0. Here, by sequencing the genome of
Externí odkaz:
https://doaj.org/article/9ce9af2626494b6fa20ba8bafc56857f
Autor:
Daniel S.K. Liu, Jisce R. Puik, Bhavik Y. Patel, Morten T. Venø, Mahrou Vahabi, Mireia Mato Prado, Jason P. Webber, Eleanor Rees, Flora M. Upton, Kate Bennett, Catherine Blaker, Benoit Immordino, Annalisa Comandatore, Luca Morelli, Shivan Sivakumar, Rutger-Jan Swijnenburg, Marc G. Besselink, Long R. Jiao, Geert Kazemier, Elisa Giovannetti, Jonathan Krell, Adam E. Frampton
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Distinguishing benign from malignant pancreaticobiliary disease is challenging because of the absence of reliable biomarkers. Circulating extracellular vesicles (EVs) have emerged as functional mediators between cells. Their cargo
Externí odkaz:
https://doaj.org/article/2f67910999e14d67b5bad68ba843ae62
Autor:
Meghan E. Willoughby, BS, Jacob L. Ramsey-Morrow, MD, Kyle A. Littell, MD, Flora M. Hammond, MD
Publikováno v:
Archives of Rehabilitation Research and Clinical Translation, Vol 6, Iss 2, Pp 100332- (2024)
Objective: To describe the outcomes (change in functional independence and discharge disposition) of patients who after liver transplantation received acute inpatient rehabilitation in a freestanding rehabilitation hospital. Design: A retrospective c
Externí odkaz:
https://doaj.org/article/2dea9406238c4440afa944a27ee6218c
Autor:
Davide Capauto, Yifan Wang, Feinan Wu, Scott Norton, Jessica Mariani, Fumitaka Inoue, Gregory E. Crawford, Nadav Ahituv, Alexej Abyzov, Flora M. Vaccarino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Regulation of gene expression through enhancers is one of the major processes shaping the structure and function of the human brain during development. High-throughput assays have predicted thousands of enhancers involved in neurodevelopment
Externí odkaz:
https://doaj.org/article/ca2e76102a6a4aa197468ba562562414
Autor:
McKinzie A. Garrison, Yeongjun Jang, Taejeong Bae, Adriana Cherskov, Sarah B. Emery, Liana Fasching, Attila Jones, John B. Moldovan, Cindy Molitor, Sirisha Pochareddy, Mette A. Peters, Joo Heon Shin, Yifan Wang, Xiaoxu Yang, Schahram Akbarian, Andrew Chess, Fred H. Gage, Joseph G. Gleeson, Jeffrey M. Kidd, Michael McConnell, Ryan E. Mills, John V. Moran, Peter J. Park, Nenad Sestan, Alexander E. Urban, Flora M. Vaccarino, Christopher A. Walsh, Daniel R. Weinberger, Sarah J. Wheelan, Alexej Abyzov, BSMN Consortium
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-18 (2023)
Abstract Somatic mosaicism is defined as an occurrence of two or more populations of cells having genomic sequences differing at given loci in an individual who is derived from a single zygote. It is a characteristic of multicellular organisms that p
Externí odkaz:
https://doaj.org/article/169288af9ac84d8b8a7875b0a5f4336c
Autor:
Flora M. Hammond, Jessica M. Ketchum, Vipul Vinod Patni, Bijan Nejadnik, Damien Bates, Alan H. Weintraub
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 447-457 (2023)
The Extended Glasgow Outcome Scale (GOSE) is accepted as the primary outcome measure in registrational studies for traumatic brain injury (TBI). The Disability Rating Scale (DRS) is used to assess functional progress from initial acute injury, throug
Externí odkaz:
https://doaj.org/article/01d9d8e00e174f6c92f446969585841e
Autor:
Hanna E. Stevens, Soraya Scuderi, Sarah C. Collica, Simone Tomasi, Tamas L. Horvath, Flora M. Vaccarino
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Fibroblast growth factor receptor 2 (FGFR2) is almost exclusively expressed in glial cells in postnatal mouse brain, but its impact in glia for brain behavioral functioning is poorly understood. We compared behavioral effects from FGFR2 loss
Externí odkaz:
https://doaj.org/article/24fca8045f194d03bdf9c4af93006b7f
Autor:
Pietro Impellizzeri, Flora M. Peri, Salvatore Arena, Renato Trimarchi, Carmelo Romeo, Gianlorenzo Dionigi
Publikováno v:
Annals of Pediatric Surgery, Vol 18, Iss 1, Pp 1-5 (2022)
Abstract Background data Ganglioneuroma is rare in children and often incidentally discovered. The transperitoneal laparoscopic approach is the surgical choice for most of the surgeons because of the familiar anatomy and the wider working spaces. How
Externí odkaz:
https://doaj.org/article/ef632158e68649e28f8e59cd9b09b98c
Autor:
Yifan Wang, Taejeong Bae, Jeremy Thorpe, Maxwell A. Sherman, Attila G. Jones, Sean Cho, Kenneth Daily, Yanmei Dou, Javier Ganz, Alon Galor, Irene Lobon, Reenal Pattni, Chaggai Rosenbluh, Simone Tomasi, Livia Tomasini, Xiaoxu Yang, Bo Zhou, Schahram Akbarian, Laurel L. Ball, Sara Bizzotto, Sarah B. Emery, Ryan Doan, Liana Fasching, Yeongjun Jang, David Juan, Esther Lizano, Lovelace J. Luquette, John B. Moldovan, Rujuta Narurkar, Matthew T. Oetjens, Rachel E. Rodin, Shobana Sekar, Joo Heon Shin, Eduardo Soriano, Richard E. Straub, Weichen Zhou, Andrew Chess, Joseph G. Gleeson, Tomas Marquès-Bonet, Peter J. Park, Mette A. Peters, Jonathan Pevsner, Christopher A. Walsh, Daniel R. Weinberger, Brain Somatic Mosaicism Network, Flora M. Vaccarino, John V. Moran, Alexander E. Urban, Jeffrey M. Kidd, Ryan E. Mills, Alexej Abyzov
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-32 (2021)
Abstract Background Post-zygotic mutations incurred during DNA replication, DNA repair, and other cellular processes lead to somatic mosaicism. Somatic mosaicism is an established cause of various diseases, including cancers. However, detecting mosai
Externí odkaz:
https://doaj.org/article/ed8ec2a7cb594e94ba5848bb9fd9be5a
Autor:
Flora M. Antunes, Manuel S. Malmierca
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
The corticothalamic (CT) pathways emanate from either Layer 5 (L5) or 6 (L6) of the neocortex and largely outnumber the ascending, thalamocortical pathways. The CT pathways provide the anatomical foundations for an intricate, bidirectional communicat
Externí odkaz:
https://doaj.org/article/d058614d717a4186b5952d3ae075061f