Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Flora Donati"'
Autor:
Delphine Planas, Isabelle Staropoli, Vincent Michel, Frederic Lemoine, Flora Donati, Matthieu Prot, Francoise Porrot, Florence Guivel-Benhassine, Banujaa Jeyarajah, Angela Brisebarre, Océane Dehan, Léa Avon, William Henry Bolland, Mathieu Hubert, Julian Buchrieser, Thibault Vanhoucke, Pierre Rosenbaum, David Veyer, Hélène Péré, Bruno Lina, Sophie Trouillet-Assant, Laurent Hocqueloux, Thierry Prazuck, Etienne Simon-Loriere, Olivier Schwartz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral sublineages. Here, we isolate and characterize XBB.1, XBB.1.5, XBB.1.9.1, XBB.1.16.1, EG.5.1.1, EG.5.1.3, XBF, BA.2.86.1 and JN.1 variants, representing
Externí odkaz:
https://doaj.org/article/8234f50bbc5043a1a52a4adceb8cfad0
Autor:
Cyril Planchais, Ignacio Fernández, Benjamin Chalopin, Timothée Bruel, Pierre Rosenbaum, Maxime Beretta, Jordan D. Dimitrov, Laurine Conquet, Flora Donati, Matthieu Prot, Françoise Porrot, Delphine Planas, Isabelle Staropoli, Florence Guivel-Benhassine, Eduard Baquero, Sylvie van der Werf, Ahmed Haouz, Etienne Simon-Lorière, Xavier Montagutelli, Bernard Maillère, Félix A. Rey, Pablo Guardado-Calvo, Hervé Nozach, Olivier Schwartz, Hugo Mouquet
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110354- (2024)
Summary: Antibodies play a pivotal role in protecting from SARS-CoV-2 infection, but their efficacy is challenged by the continuous emergence of viral variants. In this study, we describe two broadly neutralizing antibodies cloned from the memory B c
Externí odkaz:
https://doaj.org/article/c653ff8957ad4f029dc47c33231f0107
Autor:
Aurélien Marc, Romain Marlin, Flora Donati, Mélanie Prague, Marion Kerioui, Cécile Hérate, Marie Alexandre, Nathalie Dereuddre-Bosquet, Julie Bertrand, Vanessa Contreras, Sylvie Behillil, Pauline Maisonnasse, Sylvie Van Der Werf, Roger Le Grand, Jérémie Guedj
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1010721 (2023)
The impact of variants of concern (VoC) on SARS-CoV-2 viral dynamics remains poorly understood and essentially relies on observational studies subject to various sorts of biases. In contrast, experimental models of infection constitute a powerful mod
Externí odkaz:
https://doaj.org/article/9cc6ae673b14459eb5cbc824b3092773
Autor:
Cécile Hérate, Romain Marlin, Franck Touret, Nathalie Dereuddre-Bosquet, Flora Donati, Francis Relouzat, Laura Junges, Mathilde Galhaut, Océane Dehan, Quentin Sconosciuti, Antoine Nougairède, Xavier de Lamballerie, Sylvie van der Werf, Roger Le Grand
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16664- (2023)
The SARS-CoV2 Omicron variants have acquired new Spike mutations leading to escape from the most of the currently available monoclonal antibody treatments reducing the options for patients suffering from severe Covid-19. Recently, both in vitro and i
Externí odkaz:
https://doaj.org/article/4e34389eacbf456083eb7358dd586261
Autor:
Alice Mac Kain, Ghizlane Maarifi, Sophie-Marie Aicher, Nathalie Arhel, Artem Baidaliuk, Sandie Munier, Flora Donati, Thomas Vallet, Quang Dinh Tran, Alexandra Hardy, Maxime Chazal, Françoise Porrot, Molly OhAinle, Jared Carlson-Stevermer, Jennifer Oki, Kevin Holden, Gert Zimmer, Etienne Simon-Lorière, Timothée Bruel, Olivier Schwartz, Sylvie van der Werf, Nolwenn Jouvenet, Sébastien Nisole, Marco Vignuzzi, Ferdinand Roesch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here, Mac Kain and Maarifi et al. perform a functional CRISPR/Cas9 screen to identify SARS-CoV-2 restriction factors in A549 cells. They identify DAXX, a scaffold protein of nuclear bodies with diverse functions, that has anti-viral activity post SAR
Externí odkaz:
https://doaj.org/article/2979f6b8098645b5aa9271d3426c5eed
Autor:
Franck Touret, Emilie Giraud, Jérôme Bourret, Flora Donati, Jaouen Tran-Rajau, Jeanne Chiaravalli, Frédéric Lemoine, Fabrice Agou, Etienne Simon-Lorière, Sylvie van der Werf, Xavier de Lamballerie
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106413- (2023)
Summary: The landscape of SARS-CoV-2 variants dramatically diversified with the simultaneous appearance of multiple subvariants originating from BA.2, BA.4, and BA.5 Omicron sub-lineages. They harbor a specific set of mutations in the spike that can
Externí odkaz:
https://doaj.org/article/1bbb298c8e25422ebe9435705eccb535
Autor:
Marine Wasniewski, Franck Boué, Céline Richomme, Etienne Simon-Lorière, Sylvie Van der Werf, Flora Donati, Vincent Enouf, Yannick Blanchard, Véronique Beven, Estelle Leperchois, Bryce Leterrier, Sandrine Corbet, Meriadeg Le Gouil, Elodie Monchatre-Leroy, Evelyne Picard-Meyer
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0290444 (2023)
Soon after the beginning of the COVID-19 pandemic in early 2020, the Betacoronavirus SARS-CoV-2 infection of several mink farms breeding American minks (Neovison vison) for fur was detected in various European countries. The risk of a new reservoir b
Externí odkaz:
https://doaj.org/article/cbd0da01ff4b43149f62e0bca06b6ef1
Autor:
Antonio Gonçalves, Pauline Maisonnasse, Flora Donati, Mélanie Albert, Sylvie Behillil, Vanessa Contreras, Thibaut Naninck, Romain Marlin, Caroline Solas, Andres Pizzorno, Julien Lemaitre, Nidhal Kahlaoui, Olivier Terrier, Raphael Ho Tsong Fang, Vincent Enouf, Nathalie Dereuddre-Bosquet, Angela Brisebarre, Franck Touret, Catherine Chapon, Bruno Hoen, Bruno Lina, Manuel Rosa Calatrava, Xavier de Lamballerie, France Mentré, Roger Le Grand, Sylvie van der Werf, Jérémie Guedj
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 3, p e1008785 (2021)
Non-human primates infected with SARS-CoV-2 exhibit mild clinical signs. Here we used a mathematical model to characterize in detail the viral dynamics in 31 cynomolgus macaques for which nasopharyngeal and tracheal viral load were frequently assesse
Externí odkaz:
https://doaj.org/article/0fa0b9d2f5e5421e8a4721a215607b84
Autor:
Sylvie Behillil, Dominique Rousset, Flora Donati, Laurine Levillayer, Grégory Jouvion, Jean Jaubert, Xavier Montagutelli, Vincent Enouf, Mélanie Albert, Sylvie van der Werf, Fabiana Gámbaro, Eduard Baquero Salazar, Etienne Simon-Loriere, Félix A. Rey, Laurine Conquet, Matthieu Prot
Receptor recognition is a major determinant of viral host range, as well as infectivity and pathogenesis. Emergences have been associated with serendipitous events of adaptation upon encounters with a novel host, and the high mutation rate of RNA vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30176bbada69ceadfe08934b62935959
https://hal-pasteur.archives-ouvertes.fr/pasteur-04168583/file/2021.03.18.436013v2.full.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-04168583/file/2021.03.18.436013v2.full.pdf
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19
Autor:
Sarah Temmam, Xavier Montagutelli, Cécile Herate, Flora Donati, Béatrice Regnault, Mikael Attia, Eduard Baquero Salazar, Delphine Chretien, Laurine Conquet, Grégory Jouvion, Juliana Pipoli Da Fonseca, Thomas Cokelaer, Faustine Amara, Francis Relouzat, Thibaut Naninck, Julien Lemaitre, Nathalie Derreudre‐Bosquet, Quentin Pascal, Massimiliano Bonomi, Thomas Bigot, Sandie Munier, Felix A Rey, Roger Le Grand, Sylvie van der Werf, Marc Eloit
Publikováno v:
EMBO Reports
EMBO Reports, 2023, 24 (4), pp.e56055. ⟨10.15252/embr.202256055⟩
EMBO Reports, 2023, 24 (4), pp.e56055. ⟨10.15252/embr.202256055⟩
International audience; Bat sarbecovirus BANAL-236 is highly related to SARS-CoV-2 and infects human cells, albeit lacking the furin cleavage site in its spike protein. BANAL-236 replicates efficiently and pauci-symptomatically in humanized mice and